Results 201 to 210 of about 778,322 (318)

Persistently raised aspartate aminotransferase (AST) due to macro-AST in a rheumatology clinic [PDF]

, 2015
Wycliffe Mbagaya, Joanne Foo, Ahai Luvai, Claire King, Sarah Mapplebeck, Andrew Gough, Nuthar Jassam   +6 more
openalex   +1 more source

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

Advanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong, Fang Liu, Dawei Wang, Yanfen Li, Man Zhang, Yuting Zhou, Gengshen Song   +6 more
wiley   +1 more source

Assessment of AST to platelet ratio index (APRI) and albumin-bilirubin score (ALBI) in patients with colorectal cancer: A stage-wise analysis [PDF]

Bahareh Shateri Amiri, Mohammad Sadegh Bazgoshaeyan, Younes Robati, Ahmad Ghasemi, Amirali Shababi, Hanieh Radkhah   +5 more
openalex   +1 more source

Novel Vascularized Human Liver Organoids for Modeling Alcohol‐Induced Liver Injury and Developing Hepatoprotective Therapy

Advanced Science, EarlyView.
This study successfully engineered vascularized liver organoids (3HLOs) by co‐culturing human reprogrammed hepatocyte‐like cells (hrHLs) with human umbilical vein endothelial cells (HUVECs) and human umbilical mesenchymal stem cells (HUMSCs). Upon implantation, the 3HLOs established functional vascular anastomosis with the host circulation and ...
Kangdi Yang, Xiayan Chu, Xuerui Wang, Wenkun Zhang, Jinnuo Lu, Chuting Xu, Shoucheng Hu, Guoyu Pan, Chih‐Tsung Yang, Xiaohui Zhang, Shaojin Li, Zhaobin Guo, Hanyang Liu, Guangbo Ge   +13 more
wiley   +1 more source

Machine learning-based lineage prediction from antimicrobial susceptibility testing phenotypes for <i>Escherichia coli</i> sequence type 131 clade C surveillance across infection types. [PDF]

Microb Genom
Ross TA, Pöntinen AK, Holsbø E, Samuelsen Ø, Hegstad K, Kampffmeyer M, Corander J, Gladstone RA.   +7 more
europepmc   +1 more source

Effects of Oral Adsorbent AST-120 (Kremezin®)on the Progression of Chronic Kidney Disease

, 2010
Yong Kyu Lee, Sung Jin Moon, Hye Rim An, Jwa Kyung Kim, Sung Chang Bae, Beom Seok Kim, Hyeong Cheon Park, Sung Kyu Ha   +7 more
openalex   +1 more source

Global model structures for $\ast$-modules [PDF]

, 2019
Benjamin Böhme
openalex   +1 more source

Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription

Advanced Science, EarlyView.
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen, Fajuan Rui, Zhiwen Fan, Hongju Yang, Nan Geng, Chenqi Lu, Wenjing Ni, Yue Huan, Junping Shi, Chao Wu, Shengxia Yin, Wei An, Xia Lu, Qianwen Zhao, Jie Li   +14 more
wiley   +1 more source

Comparative Evaluation of the Effects of Oral Anti-hyperglycemic Agents and an Ayurvedic Hepatoprotective Agent in a Rat Model of Non-alcoholic Fatty Liver Disease (NAFLD). [PDF]

Cureus
Kalra SSS, Sadasivam B, Najmi A, Chaurasia JK.   +3 more
europepmc   +1 more source

ETV1 Drives CD4+ T Cell‐Mediated Intestinal Inflammation in Inflammatory Bowel Disease Through Amino Acid Transporter Slc7a5

Advanced Science, EarlyView.
This study identifies the transcription factor ETV1 as a key driver of CD4⁺ T cell‐mediated intestinal inflammation in inflammatory bowel disease (IBD). ETV1 promotes CD4⁺ T cell activation, proliferation, and Th17 differentiation by activating the amino acid transporter SLC7A5, fueling metabolic reprogramming.
Yan Shi, Song Wang, Yuqing Yan, Wei Chen, Yingying Cao, Dafan Chen, Wei Chen, Caiyun Ma, Xinjian Wan   +8 more
wiley   +1 more source