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Asthma is the most common inflammatory disease of the lungs. The prevalence of asthma is increasing in many parts of the world that have adopted aspects of the Western lifestyle, and the disease poses a substantial global health and economic burden. Asthma involves both the large-conducting and the small-conducting airways, and is characterized by a ...
Holgate, Stephen T. +5 more
+11 more sources
This article presents the complexity of asthma and its ensuing management. The author details the clinical presentation of asthma, discussing its variability of presentation over time and within and among individuals. Pathophysiology is discussed, including immunohistopathologic features and inflammatory mediators, risk factors, comorbid conditions ...
Rodolfo M, Pascual, Stephen P, Peters
+10 more sources
Background Air pollution harms health across the life course. Children are at particular risk of adverse effects during development, which may impact on health in later life.
Ivelina Tsocheva +36 more
doaj +1 more source
Plain English summary There are more Black people with asthma in the US than White people. Black people have more hospital stays or deaths from asthma than White people. This highlights the need for Black people to be involved in research.
LeRoy Graham +6 more
doaj +1 more source
"From the Pages of AllergyWatch" is devoted to publishing synopses of Allergy and Asthma literature relevant to a topic of emphasis. These unbiased synopses and comments by our Editors have been previously printed in the AllergyWatch bimonthly newsletter, and it is our hope that presenting carefully selected article summaries and comments in the Annals
David A, Khan +3 more
+10 more sources
Asthma-one of the most common chronic, non-communicable diseases in children and adults-is characterised by variable respiratory symptoms and variable airflow limitation. Asthma is a consequence of complex gene-environment interactions, with heterogeneity in clinical presentation and the type and intensity of airway inflammation and remodelling.
Papi, Alberto +3 more
openaire +8 more sources
Background Despite the evidence-based guidelines promoted by the Global Initiative for Chronic Obstructive Lung Disease (GOLD), the overuse of prescription drugs to manage COPD, particularly inhaled corticosteroids (ICS), remains a persistent challenge ...
Fortune O. Alabi +7 more
doaj +1 more source
Spermidine and spermine exert protective effects within the lung
Asthma is a heterologous disease that is influenced by complex interactions between multiple environmental exposures, metabolism, and host immunoregulatory processes. Specific metabolites are increasingly recognized to influence respiratory inflammation.
Marcin Wawrzyniak +13 more
doaj +1 more source
Background Many infants born at less than 34 weeks of gestational age will require resuscitation in the delivery suite. Yet, different resuscitation techniques are specified in different national guidelines, likely reflecting a limited evidence base. One
Katie A. Hunt +4 more
doaj +1 more source
Mast Cells in Cutaneous Allergic Vasculitis: A Case Report
Background: The mechanism of cutaneous allergic vasculitis still remains unclear, and to the best of our knowledge, no case has been reported in the literature in which the number of mast cells was examined.
Hiroaki Inamura +5 more
doaj +1 more source

