Results 1 to 10 of about 1,042,809 (296)

High cytomegalovirus serology and subsequent COPD-related mortality: a longitudinal study

ERJ Open Research, 2020
Background Positive serology for cytomegalovirus (CMV) has been associated with all-cause mortality risk but its role in COPD mortality is unknown. The objective of the present study was to assess the relationship between CMV serology and COPD mortality.
Raffaella Nenna, Jing Zhai, Samuel E. Packard, Amber Spangenberg, Duane L. Sherrill, Fernando D. Martinez, Marilyn Halonen, Stefano Guerra   +7 more
doaj   +1 more source

Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. [PDF]

, 2011
Asthma is a common disease with a complex risk architecture including both genetic and environmental factors. We performed a meta-analysis of North American genome-wide association studies of asthma in 5,416 individuals with asthma (cases) including ...
Abel, Rebekah A, Adkinson, N Franklin, Ampleford, Elizabeth J, Avila, Lydiana, Avila, Pedro C, Barnes, Kathleen C, Baurley, James W, Beaty, Terri H, Bleecker, Eugene R, Burchard, Esteban G, Busse, William W, Calhoun, William J, Capurso, Daniel, Castro, Mario, Celedón, Juan C, Chapela, Rocio, Childhood Asthma Management Program (CAMP), Childhood Asthma Research and Education (CARE) Network, Children's Health Study (CHS) and HARBORS study, Chiu, Grace Y, Chung, Kian Fan, Conti, David V, Deichmann, Klaus A, del Rio-Navarro, Blanca, Diette, Gregory B, Dunston, Georgia M, Eng, Celeste, Ezurum, Serpil C, Faruque, Mezbah U, Ford, Jean G, Galanter, Joshua, Gauderman, W James, Genetic Research on Asthma in African Diaspora (GRAAD) Study, Genetics of Asthma in Latino Americans (GALA) Study, Study of Genes-Environment and Admixture in Latino Americans (GALA2) and Study of African Americans, Asthma, Genes & Environments (SAGE), Gern, James E, Gignoux, Christopher R, Gilliland, Frank D, Graves, Penelope E, Hancock, Dana B, Hansel, Nadia N, Heinzmann, Andrea, Hernandez, Ryan D, Himes, Blanca E, Hu, Donglei, Huntsman, Scott, Israel, Elliott, Lemanske, Robert F, Levin, Albert M, Li, Xia, Li, Xingnan, Liang, Liming, London, Stephanie J, Mantese, Vito J, Martinez, Fernando D, Mathias, Rasika A, Mexico City Childhood Asthma Study (MCAAS), Meyers, Deborah A, Myers, Rachel A, Nicolae, Dan L, Ober, Carole, Raby, Benjamin A, Rafaels, Nicholas, Rodriguez-Cintron, William, Rodriquez-Santana, Jose R, Romieu, Isabelle, Ross, Kevin D, Roth, Lindsey A, Ruczinski, Ingo, Salam, Muhammad T, Shi, Min, Sienra-Monge, Juan J, Soto-Quiros, Manuel, Stern, Debra A, Study of Asthma Phenotypes and Pharmacogenomic Interactions by Race-Ethnicity (SAPPHIRE), Togias, Alkis, Torgerson, Dara G, Van Den Berg, David J, Vora, Hita, Watson, Harold R, Weiss, Scott T, Wenzel, Sally E, Williams, L Keoki   +81 more
core   +2 more sources

Cytomegalovirus serology in young to mid‐adult life and decline of lung function

The Clinical Respiratory Journal, 2023
Introduction Cytomegalovirus (CMV) seropositivity has been recently linked to severity and progression of asthma, cystic fibrosis, and chronic obstructive pulmonary disease (COPD). To date, no longitudinal study has addressed the relation of CMV serology
Raffaella Nenna, Jing Zhai, Amber Spangenberg, Duane L. Sherrill, Fernando D. Martinez, Marilyn Halonen, Stefano Guerra   +6 more
doaj   +1 more source

Expression of SMARCD1 interacts with age in association with asthma control on inhaled corticosteroid therapy. [PDF]

, 2020
BackgroundGlobal gene expression levels are known to be highly dependent upon gross demographic features including age, yet identification of age-related genomic indicators has yet to be comprehensively undertaken in a disease and treatment-specific ...
Burchard, Esteban G, Croteau-Chonka, Damien C, Dahlin, Amber, Eng, Celeste, Kelly, Rachel, Kho, Alvin T, Lu, Quan, Lutz, Sharon M, Mak, Angel CY, McGeachie, Michael J, Oh, Sam S, Panganiban, Ronald, Raby, Benjamin A, Rodriguez-Santana, Jose R, Saef, Benjamin, Sajuthi, Satria, Seibold, Max A, Sordillo, Joanne E, Tantisira, Kelan G, Urbanek, Cydney, Wang, Alberta L, Weiss, Scott T, Wu, Ann Chen   +22 more
core   +1 more source

MyAirCoach: The use of home-monitoring and mHealth systems to predict deterioration in asthma control and the occurrence of asthma exacerbations; Study protocol of an observational study [PDF]

, 2016
© Published by the BMJ Publishing Group Limited. Introduction Asthma is a variable lung condition whereby patients experience periods of controlled and uncontrolled asthma symptoms.
Bonini, Matteo, Chung, Kian Fan, Fowler, Stephen, Honkoop, Persijn J., Meah, Sally, Simpson, Andrew, Snoeck-Stroband, Jiska B., Sont, Jacob K., Usmani, Omar S.   +8 more
core   +4 more sources

A 5-year Study of Systemic Reactions Using both Shared and Patient-Specific Vaccines

Allergy & Rhinology, 2013
The safety of shared specific vaccines (SSVs) has been questioned by some experts. The purpose of this study was to evaluate the safety of SSVs. Details of systemic allergic reactions after subcutaneous immunotherapy injections were captured on a ...
Julian Melamed M.D., Ami Mehra M.D., Angela Ahuja-Malik M.D.   +2 more
doaj   +1 more source

House Dust Mite and Cat Dander Extract Induce Asthma-Like Histopathology with an Increase of Mucosal Mast Cells in a Guinea Pig Model

Journal of Immunology Research, 2023
Background. Asthma is a chronic inflammatory disease with structural changes in the lungs defined as airway remodelling. Mast cell responses are important in asthma as they, upon activation, release mediators inducing bronchoconstriction, inflammatory ...
Patricia Ramos-Ramírez, Jielu Liu, Sofia Mogren, Joshua Gregory, Malin Noreby, Anne Petrén, Ying Lei, Henric Olsson, Marianne van Hage, Jukka Kervinen, Lars Hellman, Cecilia Andersson, Gunnar Nilsson, Mikael Adner   +13 more
doaj   +1 more source

(Correcting) misdiagnoses of asthma: A cost effectiveness analysis [PDF]

, 2011
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work ...
Amanda Sumner, BN Awadh, Douglas Coyle, HM Sharpe, K Bahadori, Katherine Vandemheen, KB Weiss, L McKnight-Eily, LC O'Dowd, MD Krahn, MG Cisternas, MK Campbell, Ontario Drug Benefit Formulary/Comparative Drug Index, P Kenny, R Jin, RB Haynes, S Diaz-Lobato, S Kamble, SD Aaron, Shawn Aaron, Smita Pakhale, SP Corrigan, Statistics Canada, VP Luks, WJ Ungar   +24 more
core   +4 more sources

Evaluation of Swab-Seq as a scalable, sensitive assay for community surveillance of SARS-CoV-2 infection

Scientific Reports, 2022
The ongoing SARS-CoV-2 pandemic and subsequent demand for viral testing has led to issues in scaling diagnostic lab efforts and in securing basic supplies for collection and processing of samples. This has motivated efforts by the scientific community to
HyunJin Kang, Sheilah Allison, Amber Spangenberg, Tara Carr, Ryan Sprissler, Marilyn Halonen, Darren A. Cusanovich   +6 more
doaj   +1 more source

Feasibility of sustained response through long-term dosing in food allergy immunotherapy

Allergy, Asthma & Clinical Immunology, 2017
Background Clinical trials using oral immunotherapy (OIT) for the treatment of food allergies have shown promising results. We previously demonstrated the feasibility of desensitization for up to 5 food allergens simultaneously through OIT.
Sandra Andorf, Monali Manohar, Tina Dominguez, Whitney Block, Dana Tupa, Rohun A. Kshirsagar, Vanitha Sampath, R. Sharon Chinthrajah, Kari C. Nadeau   +8 more
doaj   +1 more source