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The Lancet, 2018 Asthma-one of the most common chronic, non-communicable diseases in children and adults-is characterised by variable respiratory symptoms and variable airflow limitation. Asthma is a consequence of complex gene-environment interactions, with heterogeneity in clinical presentation and the type and intensity of airway inflammation and remodelling.
A. Papi +3 more
semanticscholar +9 more sources
Nature Reviews Disease Primers, 2015 Asthma is the most common inflammatory disease of the lungs. The prevalence of asthma is increasing in many parts of the world that have adopted aspects of the Western lifestyle, and the disease poses a substantial global health and economic burden. Asthma involves both the large-conducting and the small-conducting airways, and is characterized by a ...
Holgate, Stephen T. +5 more
+11 more sources
Key recommendations for primary care from the 2022 Global Initiative for Asthma (GINA) update
npj Primary Care Respiratory Medicine, 2023 The Global Initiative for Asthma (GINA) was established in 1993 by the World Health Organization and the US National Heart Lung and Blood Institute to improve asthma awareness, prevention and management worldwide.
M. Levy +18 more
semanticscholar +1 more source
Respiratory Research, 2023 Background The burden of asthma in terms of premature death or reduced quality of life remains a huge issue. It is of great importance to evaluate asthma burden geographically and time trends from 1990 to 2019 and to assess the contributions of age ...
Zhufeng Wang +7 more
semanticscholar +1 more source
Otolaryngologic Clinics of North America, 2011 This article presents the complexity of asthma and its ensuing management. The author details the clinical presentation of asthma, discussing its variability of presentation over time and within and among individuals. Pathophysiology is discussed, including immunohistopathologic features and inflammatory mediators, risk factors, comorbid conditions ...
Rodolfo M, Pascual, Stephen P, Peters
+10 more sources
Research Involvement and Engagement, 2023 Plain English summary There are more Black people with asthma in the US than White people. Black people have more hospital stays or deaths from asthma than White people. This highlights the need for Black people to be involved in research.
LeRoy Graham +6 more
doaj +1 more source
Annals of Allergy, Asthma & Immunology, 2019 "From the Pages of AllergyWatch" is devoted to publishing synopses of Allergy and Asthma literature relevant to a topic of emphasis. These unbiased synopses and comments by our Editors have been previously printed in the AllergyWatch bimonthly newsletter, and it is our hope that presenting carefully selected article summaries and comments in the Annals
David A, Khan +3 more
+10 more sources
BMC Pediatrics, 2023 Background Air pollution harms health across the life course. Children are at particular risk of adverse effects during development, which may impact on health in later life.
Ivelina Tsocheva +36 more
doaj +1 more source
Global Initiative for Asthma Strategy 2021: Executive Summary and Rationale for Key Changes
European Respiratory Journal, 2021 The Global Initiative for Asthma (GINA) Strategy Report provides clinicians with an annually updated evidence-based strategy for asthma management and prevention, which can be adapted for local circumstances (e.g. medication availability).
H. Reddel +20 more
semanticscholar +1 more source
Tezepelumab in Adults and Adolescents with Severe, Uncontrolled Asthma.
New England Journal of Medicine, 2021 BACKGROUND Tezepelumab is a human monoclonal antibody that blocks thymic stromal lymphopoietin, an epithelial-cell-derived cytokine implicated in the pathogenesis of asthma.
A. Menzies-Gow +13 more
semanticscholar +1 more source