Results 101 to 110 of about 1,230,724 (345)

Recent advances in understanding rhinovirus immunity [version 1; referees: 4 approved]

F1000Research, 2018
Rhinoviruses are the most common cause of upper respiratory tract infections. However, they can induce exacerbations of chronic obstructive pulmonary disease and asthma, bronchiolitis in infants, and significant lower respiratory tract infections in ...
Spyridon Makris, Sebastian Johnston
doaj   +1 more source

IL‐4/STAT6‐signaling Influences Local Inflammation and Regeneration Processes During Acute Pancreatitis and Promotes Fibrosis by a Direct Activation of Pancreatic Fibroblasts During Chronic Pancreatitis

Advanced Science, EarlyView.
IL‐4/IL‐13/STAT6 signaling plays a crucial for the suppression of pro‐inflammation during acute pancreatitis and supports acinar cell regeneration but has only minor impact on fibrogenesis during chronic form of the disease. IL‐4/IL‐13 induce the expression of certain collagens directly in pancreatic fibroblasts via STAT6 activation, whereas ...
ElSheikh H, Salvers A, Piesker J, Buchholz S, Lange R, Ameling S, Steil L, Hammer E, Homuth G, Völker U, Bröker BM, Weiss FU, Sendler M, Glaubitz J   +13 more
wiley   +1 more source

Guideline on management of the acute asthma attack in children by Italian Society of Pediatrics. [PDF]

, 2018
BACKGROUND: Acute asthma attack is a frequent condition in children. It is one of the most common reasons for emergency department (ED) visit and hospitalization. Appropriate care is fundamental, considering both the high prevalence of asthma in children,
Chiappini, E, Corsello, G, Indinnimeo, L, Miraglia del Giudice, M   +3 more
core   +1 more source

Increased Levels of Airway Neutrophils Reduces the Inhibitory Effects of Inhaled Glucocorticosteroids on Allergen-Induced Airway Eosinophils

Canadian Respiratory Journal, 2002
BACKGROUND: Treatment with inhaled glucocorticosteroids attenuates allergen-induced airway inflammation but is less effective in people with asthma who have noneosinophilic airway inflammation.
Gail M Gauvreau, Mark D Inman, Margaret Kelly, Richard M Watson, Sandra C Dorman, Paul M O’Byrne   +5 more
doaj   +1 more source

OTUD6A in Airway Epithelial Cells Exacerbates Allergic Asthma by Promoting Airway Inflammation and Airway Remodeling Through Deubiquitination of hResistin/mRELMα

Advanced Science, EarlyView.
This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan, Xinru Xi, Wei Dai, Tingfang Xiao, Yeqing Chen, Xuanyu Chen, Xiangting Ge, Chengguang Zhao, Hui Zhang, Yali Zhang, Weixi Zhang   +10 more
wiley   +1 more source

Allergens, germs and asthma [PDF]

, 2015
Objective To explore asthma pathogenesis using data from upper and lower airways. Data Source English-language papers on human asthma and nasal polyp subjects from 1990 onwards.
Scadding, GK
core  

Case report presenting the diagnostic challenges in a patient with recurrent acquired angioedema, antiphospholipid antibodies and undetectable C2 levels

Allergy, Asthma & Clinical Immunology, 2018
Background Angioedema secondary to acquired C1 inhibitor deficiency (AAE) is a rare disease. It usually is associated with lymphoproliferative disorders.
Arturo J. Bonnin, Charles DeBrosse, Terri Moncrief, G. Wendell Richmond   +3 more
doaj   +1 more source

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

Advanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta, Jonas Bossart, Sènan Mickael D'Almeida, Luis Augusto Visani de Luna, Christoph Schwärzler, Tingting Fu, Vanesa Ayala‐Nunez, Alexander Gogos, Marija Buljan, Vera M Kissling, Emmanuel Flahaut, Miguel Garcia, Cyrill Bussy, Peter Wick, Tina Buerki‐Thurnherr   +14 more
wiley   +1 more source

Walkie talkies to aid health care workers’ compliance with personal protective equipment in the fight against COVID-19

Critical Care, 2020
Dominic Fenn, Jonny Coppel, Jessica Kearney, Lucy Everson, Simon Braithwaite, Rahul Chodhari   +5 more
doaj   +1 more source

Role of interleukin‐13 in eosinophil accumulation and airway remodelling in a mouse model of chronic asthma [PDF]

, 2002
Rakesh Kumar, Cristan Herbert, Ming Yang, Aulikki Koskinen, Andrew N. J. McKenzie, Paul S. Foster   +5 more
openalex   +1 more source