Results 131 to 140 of about 887,968 (372)
A remote hypertension management program clinical algorithm
Abstract Introduction Hypertension is the leading risk factor for death, affecting over one billion people worldwide, yet control rates are poor and stagnant. We developed a remote hypertension management program that leverages digitally transmitted home blood pressure (BP) measurements, algorithmic care pathways, and patient–navigator communications ...
Hunter Nichols+3 more
wiley +1 more source
Prediction of Individual Outcomes for Asthma Sufferers [PDF]
We consider the problem of individual-specific medication level recommendation (initiation, removal, increase, or decrease) for asthma sufferers. Asthma is one of the most common chronic diseases in both adults and children, affecting 8% of the US population and costing $37-63 billion/year in the US.
arxiv
The older population has seen the greatest increase in the prevalence of current asthma in recent years. Asthma may begin at any age and when it occurs at an advanced as opposed to a young age, it is often nonatopic, severe, and unremitting. Unfortunately, geriatric-specific guidelines are not available for the diagnosis and treatment of asthma ...
openaire +5 more sources
AbstractBronchial asthma is now recognised to be a major cause of morbidity and even mortality in people of all ages. Two important ideas have changed our approach to asthma management. The first is understanding that asthma is a chronic inflammatory disorder which needs regular treatment with anti-inflammatory drugs such as inhaled corticosteroids to ...
openaire +2 more sources
A New EP300‐Related Syndrome With Prominent Developmental and Immune Phenotypes
ABSTRACT Rubinstein Taybi syndrome (RTS) is a disorder of chromatin remodeling and transcriptional regulation caused by heterozygous pathogenic variants in CREBBP and EP300. RTS is characterized by a distinct facial gestalt, intellectual disability, structural kidney and heart differences, feeding difficulties, and broad thumbs and great toes ...
Devi Priyanka Maripuri+3 more
wiley +1 more source
Abstract The bioequivalence of a generic fudosteine tablet vs a brand‐named fudosteine tablet under fasting and fed conditions was evaluated in this study. This randomized, open‐label, single‐dose, 4‐way replicate, crossover, bioequivalence study included 64 healthy Chinese subjects (fasting cohort, n = 32; fed cohort, n = 32) who were assigned to ...
Mingxue Zhu+6 more
wiley +1 more source
Eosinophilic inflammation in asthma.
BACKGROUND AND METHODS The importance of eosinophils in the pathogenesis of bronchial asthma is not established. In an attempt to evaluate the role of eosinophilic inflammation in asthma, we compared 10 normal subjects with 43 patients with chronic ...
J. Bousquet+10 more
semanticscholar +1 more source
Children With 22.Q.11.2 Deletion Syndrome: Sleep‐Disordered Breathing and Management
ABSTRACT Patients with 22q11.2 deletion syndrome (22q11DS) are predisposed to obstructive sleep apnea (OSA) due to an abnormal craniofacial anatomy with pharyngeal hypotonia, retrognathia, micrognathia, and glossoptosis. The aim of the study was to describe the prevalence and management of OSA in a cohort of children with 22q11DS.
Domenico Paolo La Regina+6 more
wiley +1 more source
Simultaneous Broadband Suppression of Homonuclear and Heteronuclear Couplings in 1H NMR Spectroscopy
Ultra‐high resolution 1H NMR spectra are obtained by simultaneous broadband suppression of both homonuclear and heteronuclear scalar couplings, giving a fully pure shift 1H NMR spectrum containing chemical shift information only. The analysis of a range of fluorine‐ and phosphorus‐containing systems highlights how this method can be used to aid the ...
Coral Mycroft+3 more
wiley +1 more source
Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma.
BACKGROUND Many patients with severe asthma require regular treatment with oral glucocorticoids despite the use of high-dose inhaled therapy. However, the regular use of systemic glucocorticoids can result in serious and often irreversible adverse ...
E. Bel+7 more
semanticscholar +1 more source