Results 131 to 140 of about 1,522,848 (395)

Walkie talkies to aid health care workers’ compliance with personal protective equipment in the fight against COVID-19

Critical Care, 2020
Dominic Fenn, Jonny Coppel, Jessica Kearney, Lucy Everson, Simon Braithwaite, Rahul Chodhari   +5 more
doaj   +1 more source

EAACI Guidelines on Allergen Immunotherapy: House dust mite‐driven allergic asthma

Allergy. European Journal of Allergy and Clinical Immunology, 2019
Allergen immunotherapy (AIT) has been in use for the treatment of allergic disease for more than 100 years. Asthma treatment relies mainly on corticosteroids and other controllers recommended to achieve and maintain asthma control, prevent exacerbations,
I. Agache, S. Lau, C. Akdis, S. Smolińska, M. Bonini, O. Cavkaytar, B. Flood, P. Gajdanowicz, K. Izuhara, O. Kalayci, R. Mosges, Ó. Palomares, N. Papadopoulos, M. Sokolowska, E. Angier, M. Fernández-Rivas, G. Pajno, O. Pfaar, G. Roberts, D. Ryan, G. Sturm, R. van Ree, E. Varga, R. V. van Wijk, J. Yepes-Nuñez, M. Jutel   +25 more
semanticscholar   +1 more source

Variations in Innate Immune Cell Subtypes Correlate with Epigenetic Clocks, Inflammaging and Health Outcomes

Advanced Science, EarlyView.
This study uses a high‐resolution DNA methylation reference panel for 19 immune cell‐types, as well as transcriptomic, metabolomic, and large population cohort data to show that age‐related epigenetic heterogeneity within monocytes correlates with inflammaging, biological age, and all‐causemortality, and does so more strongly than existing monocyte ...
Xiaolong Guo, Josephine A. Robertson, Andrea Aparicio, Kirsten Seale, Qingwen Chen, Anne Richmond, Zhaozhen Du, Mahnoor Sulaiman, Shijie C Zheng, Esteban Ballestar, Charlotte AM Cecil, Bastiaan T Heijmans, Steve Horvath, Varun B. Dwaraka, Jessica Lasky‐Su, Ryan Smith, Riccardo E. Marioni, Andrew E Teschendorff   +17 more
wiley   +1 more source

Oxidative Stress in Asthma

World Allergy Organization Journal, 2011
Asthma is a chronic inflammatory lung disease that results in airflow limitation, hyperreactivity, and airway remodeling. There is strong evidence that an imbalance between the reducing and oxidizing systems favoring a more oxidative state is present in ...
Umit M. Sahiner, MD, Esra Birben, PhD, Serpil Erzurum, MD, Cansin Sackesen, MD, Omer Kalayci, MD   +4 more
doaj   +1 more source

Allergens, germs and asthma [PDF]

, 2015
Objective To explore asthma pathogenesis using data from upper and lower airways. Data Source English-language papers on human asthma and nasal polyp subjects from 1990 onwards.
Scadding, GK
core  

Observations on Asthma [PDF]

, 1925
C. P. Lapage, Francis Adams
openalex   +1 more source

CXCR1 Depletion in Ly6C+ cDC2 Alleviates Acute Lung Injury via Modulation of Th17/Treg Balance

Advanced Science, EarlyView.
Pro‐inflammatory Ly6C⁺ cDC2s are identified as key effector cells mediating Cxcr1 signaling, driving the progression of ALI. Ly6C⁺ cDC2s release high levels of Il‐6 and Il‐1β, inducing Th17 differentiation. Cxcr1 deficiency reduces Il‐6 and Il‐1β production from Ly6C⁺ cDC2s through suppressing MEK1/ERK /NF‐κB signaling, thereby shifts naïve T cells ...
Shenghui Li, Wei Zhuang, Yang Wang, Hao Qin, Xichun Qin, Xianliang Yan, Xuefei Hu, Xiucheng Liu, Chang Chen   +8 more
wiley   +1 more source

Über die Beziehungen der Bronchitis fibrinosa oder mucinosa plastica und des Asthmas zur chronischen Lungentuberkulose [PDF]

, 1920
Georg Schröder
openalex   +1 more source

Type 2 Diabetes‐Associated Phenylacetylglutamine Induces Deleterious Inflammation Cycle in Myeloid Cells through β2 Adrenergic Receptors and Impedes Wound Healing

Advanced Science, EarlyView.
The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang, Xinran Ye, Chia‐Kang Ho, Ya Gao, Dongsheng Wen, Jiaming Sun, Yuxin Liu, Yangdan Liu, Guoyuan Wang, Yangbai Sun, Jinyan Zhang, Yifan Zhang, Qingfeng Li   +12 more
wiley   +1 more source

Clinical Models to Compare the Safety and Efficacy of Inhaled Corticosteroids in Patients with Asthma

Canadian Respiratory Journal, 2003
There is no consensus on the methods to compare the clinical efficacy of different inhaled corticosteroids. A comparison needs to be made in terms of relative potency, and studies should include two-, or preferably, three-dose comparisons.
Krishnan Parameswaran, Richard Leigh, Paul M O'Byrne, Margaret M Kelly, Charlie H Goldsmith, Frederick E Hargreave, Myrna Dolovich   +6 more
doaj   +1 more source