Results 131 to 140 of about 557,454 (176)
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims We studied the prevalence of psychotropic use and psychotropic polypharmacy in persons with Parkinson's disease (PD) during a 10‐year follow‐up, because longitudinal studies on this topic are scarce although non‐motor symptoms of PD are often treated with psychotropics.
Noora Nieminen +4 more
wiley +1 more source
Brain Health, EarlyView.ABSTRACT Introduction Residential environments have been linked to brain structure, particularly in children, older adults, and clinical populations. However, little is known about how different dimensions of the housing environment relate to brain white matter microstructure in healthy adults, or whether specific environmental factors show stronger ...
Keisuke Kokubun +3 more
wiley +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Index of microcirculatory resistance (IMR) is a cutting‐edge, wire‐based tool that advances the capability assessment of coronary microvascular function. By utilizing distal coronary pressure and mean transit time under maximal hyperemia, IMR delivers consistent, reproducible insights into the microvasculature's dynamic health.
Joanna Sohn +10 more
wiley +1 more source
Chronic Diseases and Translational Medicine, EarlyView.Prevalence (%) of different morbidities in the Irish Health Survey 2019. Note: Asthma, bronchitis (chronic bronchitis or chronic obstructive pulmonary disease or emphysema), heart attack (heart attack or chronic consequences of heart attack), CHD (coronary heart disease or angina pectoris), HBP (high blood pressure), stroke (stroke or the chronic ...
Alwalid Ali, Santosh Sharma
wiley +1 more source
Pharmaceuticals Made with Hydrogen: A Sustainable and Efficient Approach Using Flow Synthesis
Chemistry – A European Journal, EarlyView.We demonstrate a sustainable strategy for pharmaceutical manufacturing by combining hydrogen, heterogeneous catalysis, and continuous flow synthesis. The development of novel catalysts and their application in a multi‐step synthesis of donepezil enabled a highly productive process with no intermediate purification.
Shū Kobayashi, Haruro Ishitani
wiley +1 more source
Financial Toxicity Associated with Biological Medicines: A Scoping Review
Clinical Pharmacology &Therapeutics, EarlyView.Financial toxicity, defined as the economic burden experienced by patients due to medication and other healthcare costs and their consequences, such as material, psychosocial and behavioral effects, represents a significant concern for individuals receiving biological medicines.
Laura Sara Maria Saarukka +4 more
wiley +1 more source
RORγt‐APCs: The New Masters of Oral Tolerance
Barrier Immunity, EarlyView.ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley +1 more source
Association of COPD with adverse outcomes in heart failure patients with preserved ejection fraction
ESC Heart Failure, Volume 12, Issue 2, Page 799-808, April 2025.Abstract We performed a systematic review and meta‐analysis to detect the impact of chronic obstructive pulmonary disease (COPD) on the prognosis of heart failure patients with preserved ejection fraction (HFpEF). We systematically screened eligible literature from three electronic databases, PubMed, EMBASE and Cochrane Library, up to April 2023.
Shuo Xu +3 more
wiley +1 more source