Results 161 to 170 of about 887,968 (372)

Superior Benefits of Combining Mepolizumab With Sinus Surgery Compared to Mepolizumab Alone: Results From a Randomised 6‐Month Trial

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) significantly impacts patients’ quality of life (QoL). Standard treatments include nasal irrigations, nasal steroids, systemic corticosteroids, and functional endoscopic sinus surgery (FESS).
Anne‐Sophie Homøe   +7 more
wiley   +1 more source

Habits vs Environment: What really causes asthma? [PDF]

open access: yesarXiv, 2016
Despite considerable number of studies on risk factors for asthma onset, very little is known about their relative importance. To have a full picture of these factors, both categories, personal and environmental data, have to be taken into account simultaneously, which is missing in previous studies. We propose a framework to rank the risk factors from
arxiv  

Pulmonary Function in Left Ventricular Failure, Including Cardiac Asthma [PDF]

open access: bronze, 1957
Richard S. Cosby   +3 more
openalex   +1 more source

Differential Immune Cell Infiltration in Eosinophilic and Non‐Eosinophilic CRS: Correlations With Clinical, Endoscopic, and Radiological Findings

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background The pathogenesis of inflammation in eosinophilic chronic rhinosinusitis (ECRS) and non‐eosinophilic chronic rhinosinusitis (NECRS) remains poorly understood. This study aimed to assess immune cell infiltration within the sinonasal microenvironment in these conditions.
Katarzyna Czerwaty   +5 more
wiley   +1 more source

Accounting for unobserved covariates with varying degrees of estimability in high dimensional biological data [PDF]

open access: yesarXiv, 2018
An important phenomenon in high dimensional biological data is the presence of unobserved covariates that can have a significant impact on the measured response. When these factors are also correlated with the covariate(s) of interest (i.e. disease status), ignoring them can lead to increased type I error and spurious false discovery rate estimates. We
arxiv  

Deficiency of DEK proto‐oncogene alleviates allergic rhinitis by inhibiting RhoA/Ezrin‐mediated mitochondrial fission

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Schematic diagram of the mechanism of DEK regulating RhoA activation Ezrin. Upon house dust mite (HDM) stimulation, HDM‐specific immunoglobulin E (IgE) and inflammatory factors such as interleukin 4 (IL‐4), IL‐5, IL‐13, and eosinophils increased in the nasal mucosa.
Longzhu Dai   +8 more
wiley   +1 more source

Validation of Danish registry‐cases of type 1 diabetes in women giving live birth using a clinical cohort as gold standard

open access: yesEndocrinology, Diabetes &Metabolism, Volume 6, Issue 1, January 2023., 2023
The aim of this study was to validate type 1 diabetes live births in the Danish national registries against a clinical cohort of confirmed cases.The study concludes that algorithms can reliably identify type 1 diabetes in pregnancy in health registries, with a PPV above 90% and completeness around 80%.
Tina Wullum Gundersen   +8 more
wiley   +1 more source

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