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Asthma-one of the most common chronic, non-communicable diseases in children and adults-is characterised by variable respiratory symptoms and variable airflow limitation. Asthma is a consequence of complex gene-environment interactions, with heterogeneity in clinical presentation and the type and intensity of airway inflammation and remodelling.
Papi, Alberto+3 more
openaire +8 more sources
Asthma is the most common respiratory disorder in Canada. Despite significant improvement in the diagnosis and management of this disorder, the majority of Canadians with asthma remain poorly controlled. In most patients, however, control can be achieved through the use of avoidance measures and appropriate pharmacological interventions.
Kim, Harold L., Mazza, Jorge
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Asthma is the most common inflammatory disease of the lungs. The prevalence of asthma is increasing in many parts of the world that have adopted aspects of the Western lifestyle, and the disease poses a substantial global health and economic burden. Asthma involves both the large-conducting and the small-conducting airways, and is characterized by a ...
Holgate, Stephen T.+5 more
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A Twin Study of Early-Childhood Asthma in Puerto Ricans [PDF]
Background:The relative contributions of genetics and environment to asthma in Hispanics or to asthma in children younger than 3 years are not well understood.Objective:To examine the relative contributions of genetics and environment to early-childhood ...
Bunyavanich, S+6 more
core +13 more sources
Does asthma impair wealth accumulation or does wealth protect against asthma? [PDF]
OBJECTIVE: We investigate the association between adult asthma and wealth, testing whether the disease impairs wealth accumulation (social selection model) or if wealth protects against asthma (social causation model).
Smith, Patricia K., Zagorsky, Jay L.
core +1 more source
Reslizumab in patients with inadequately controlled late-onset asthma and elevated blood eosinophils [PDF]
INTRODUCTION: Asthma with adult onset and elevated blood eosinophils is a difficult-to-treat subgroup. This post hoc analysis evaluated reslizumab, an anti-interleukin-5 monoclonal antibody, in patients with late-onset eosinophilic asthma.
Brusselle, Guy+3 more
core +2 more sources
Asthma represents a readily treatable disease that today is still associated with significant morbidity and mortality, much of which may be preventable with prompt and correct therapy. An understanding of the clinical presentations of this disease, as well as an understanding of effective, multiagent therapy, is the goal of this article.
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Monitoring asthma in childhood : Lung function, bronchial responsiveness and inflammation [PDF]
Peer reviewedPublisher ...
ERS Task Force Monitoring Asthma in Children
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This review provides an evidence-based guide for the diagnosis, evaluation, and treatment of patients with asthma. It addresses typical questions that arise in the clinic-based care of patients with asthma and provides a basic and comprehensive resource for asthma care.
Patel, Shilpa J., Teach, Stephen J.
openaire +5 more sources