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Asthma [PDF]

open access: yesThe Lancet, 2018
Asthma-one of the most common chronic, non-communicable diseases in children and adults-is characterised by variable respiratory symptoms and variable airflow limitation. Asthma is a consequence of complex gene-environment interactions, with heterogeneity in clinical presentation and the type and intensity of airway inflammation and remodelling.
A. Papi   +3 more
semanticscholar   +9 more sources

Asthma [PDF]

open access: yesNature Reviews Disease Primers, 2015
Asthma is the most common inflammatory disease of the lungs. The prevalence of asthma is increasing in many parts of the world that have adopted aspects of the Western lifestyle, and the disease poses a substantial global health and economic burden. Asthma involves both the large-conducting and the small-conducting airways, and is characterized by a ...
Holgate, Stephen T.   +5 more
  +11 more sources

Key recommendations for primary care from the 2022 Global Initiative for Asthma (GINA) update

open access: yesnpj Primary Care Respiratory Medicine, 2023
The Global Initiative for Asthma (GINA) was established in 1993 by the World Health Organization and the US National Heart Lung and Blood Institute to improve asthma awareness, prevention and management worldwide.
M. Levy   +18 more
semanticscholar   +1 more source

Global, regional, and national burden of asthma and its attributable risk factors from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019

open access: yesRespiratory Research, 2023
Background The burden of asthma in terms of premature death or reduced quality of life remains a huge issue. It is of great importance to evaluate asthma burden geographically and time trends from 1990 to 2019 and to assess the contributions of age ...
Zhufeng Wang   +7 more
semanticscholar   +1 more source

Asthma [PDF]

open access: yesOtolaryngologic Clinics of North America, 2011
This article presents the complexity of asthma and its ensuing management. The author details the clinical presentation of asthma, discussing its variability of presentation over time and within and among individuals. Pathophysiology is discussed, including immunohistopathologic features and inflammatory mediators, risk factors, comorbid conditions ...
Rodolfo M, Pascual, Stephen P, Peters
  +10 more sources

Asthma

open access: yesAnnals of Allergy, Asthma & Immunology, 2019
"From the Pages of AllergyWatch" is devoted to publishing synopses of Allergy and Asthma literature relevant to a topic of emphasis. These unbiased synopses and comments by our Editors have been previously printed in the AllergyWatch bimonthly newsletter, and it is our hope that presenting carefully selected article summaries and comments in the Annals
David A, Khan   +3 more
  +10 more sources

Global Initiative for Asthma Strategy 2021: Executive Summary and Rationale for Key Changes

open access: yesEuropean Respiratory Journal, 2021
The Global Initiative for Asthma (GINA) Strategy Report provides clinicians with an annually updated evidence-based strategy for asthma management and prevention, which can be adapted for local circumstances (e.g. medication availability).
H. Reddel   +20 more
semanticscholar   +1 more source

Tezepelumab in Adults and Adolescents with Severe, Uncontrolled Asthma.

open access: yesNew England Journal of Medicine, 2021
BACKGROUND Tezepelumab is a human monoclonal antibody that blocks thymic stromal lymphopoietin, an epithelial-cell-derived cytokine implicated in the pathogenesis of asthma.
A. Menzies-Gow   +13 more
semanticscholar   +1 more source

The Global Asthma Report 2022.

open access: yesThe International Journal of Tuberculosis and Lung Disease, 2022
Published as a Supplement to the IJTLD, the 2022 Global Asthma Report (GAR), highlights the challenges of preventing and managing asthma, and reports on the gaps in asthma care in low- and middle-income countries. Cite as: The Global Asthma Report. Int J

semanticscholar   +1 more source

Sex and gender in asthma

open access: yesEuropean Respiratory Review, 2021
Asthma is a heterogenous disease, and its prevalence and severity are different in males versus females through various ages. As children, boys have an increased prevalence of asthma.
Nowrin U. Chowdhury   +3 more
semanticscholar   +1 more source

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