Results 201 to 210 of about 1,451,332 (395)

Medication adherence during the run‐in phase of clinical trials: A systematic review of methodological and reporting rigour

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Trial run‐in phases are sometimes used to select adherent participants as a strategy to enrich trials, but the methods employed lack clear regulatory guidance and there are concerns about the transparency of reporting. This review aims to characterize the methods used for adherence measurement and public reporting of run‐in studies.
Non Davies   +3 more
wiley   +1 more source

Oral corticosteroid-sparing effects of reslizumab in the treatment of eosinophilic granulomatosis with polyangiitis

open access: yesERJ Open Research, 2020
Brian D. Kent   +9 more
doaj   +1 more source

Host Cell Protein Clinical Safety Risk Assessment—An Updated Industry Review

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Host cell proteins (HCP) are process‐related impurities that can co‐purify with therapeutic proteins. Some HCP impurities potentially can have an impact on patient safety (immunogenicity or toxicity), efficacy, and/or product quality. It is important to reduce the levels of HCP impurities with a well‐controlled manufacturing process and to ...
Lisette Coye   +19 more
wiley   +1 more source

RETRACTED: Artificial intelligence for emergency medical care

open access: yesHealth Care Science, EarlyView., 2023
‘Applications of artificial intelligence in emergency medical service’. Abstract There is increasing research into the potential benefits of incorporating artificial intelligence (AI) and machine learning algorithms into emergency medical services. AI is finding new applications across a wide range of sectors, one of which is healthcare, where it is ...
Shivam Rajput   +2 more
wiley   +1 more source

Exploring Multi‐Organ Crosstalk via the TissUse HUMIMIC Chip System: Lessons Learnt So Far

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Three‐dimensional (3D) in vitro cell culture models have revolutionized biomedical research by mimicking the complex 3D in vivo environment in the human body. Different types of 3D models have been established, including heterotypic systems such as, organ‐on‐a‐chips which have been further developed into multiorgan‐on‐chip systems that ...
Filsan Ahmed Abokor   +5 more
wiley   +1 more source

Oxidative Stress in Asthma

open access: yesWorld Allergy Organization Journal, 2011
Asthma is a chronic inflammatory lung disease that results in airflow limitation, hyperreactivity, and airway remodeling. There is strong evidence that an imbalance between the reducing and oxidizing systems favoring a more oxidative state is present in ...
Umit M. Sahiner, MD   +4 more
doaj  

Home - About - Disclaimer - Privacy