Results 241 to 250 of about 1,451,332 (395)

RORγt‐APCs: The New Masters of Oral Tolerance

open access: yesBarrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

A novel transgenic reporter of extracellular acidification in zebrafish elucidates skeletal muscle T‐tubule pH regulation

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Disruption of extracellular pH and proton‐sensing can profoundly impact cellular and protein functions, leading to developmental defects. To visualize changes in extracellular pH in the developing embryo, we generated a zebrafish transgenic line that ubiquitously expresses the ratiometric pH‐sensitive fluorescent protein pHluorin2, tethered to
Leif R. Neitzel   +5 more
wiley   +1 more source

Rhinosinusitis Predispose Asthmatic Patients to Severe Bronchial Asthma [PDF]

open access: yes
In this study, we evaluated the relationship between rhinosinusitis to the severity of asthma in asthmatic patients. This cross-sectional study was conducted on 90 patients with asthma referring to Imam Khomeini Hospital in Ardabil city.
اعظمی, احد   +4 more
core  

Natural History of Asthma [PDF]

open access: green, 1949
E. O. Williams, G. E. O. Williams
openalex   +1 more source

Oral Glucocorticoid–Sparing Effect of Benralizumab in Severe Asthma

open access: yesNew England Journal of Medicine, 2017
Parameswaran Nair   +9 more
semanticscholar   +1 more source

Think highly of immunoglobulin G4‐related chronic rhinosinusitis as a clinical entity in immunoglobulin G4‐related disease

open access: yesEye &ENT Research, EarlyView.
Abstract IgG4‐related chronic rhinosinusitis (IgG4‐related CRS) is gaining recognition among various specialized physicians. As a systemic disease involving multiple organs, IgG4‐related CRS is still not widely recognized as an independent clinical entity. Given the complexity of diagnosing autoimmune‐related multisystem diseases, early recognition and
Lianqi Wan   +3 more
wiley   +1 more source

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