Results 281 to 290 of about 1,522,848 (395)

Associations Between Nicotine Metabolites and Serum Neurofilament Light Chain Levels in the General Population

open access: yesChronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Background Nicotine has been associated with cognitive functions such as memory and attention, with serum neurofilament light chain (sNfL) as a biomarker for neurological diseases such as Alzheimer's disease (AD) and multiple sclerosis (MS).
Qianqian Ji   +5 more
wiley   +1 more source

Electrochemical Breath Sensors in Medical Diagnostics: Emerging Trends and Future Directions

open access: yesChemElectroChem, EarlyView.
Electrochemical breath sensors (EBSs) are emerging as powerful tools for noninvasive health diagnostics. This perspective highlights recent advances in EBS technologies, explores their potential in mental health monitoring via gut‐derived volatile organic compounds, and outlines future directions for achieving sensitive, selective, and clinically ...
Natalie E. Strom   +2 more
wiley   +1 more source

Immune Cells Mediate the Causal Pathway Linking Multisite Chronic Pain to Asthma: A Mediation Mendelian Randomization Study. [PDF]

open access: yesJ Pain Res
Chen JH   +10 more
europepmc   +1 more source

Pharmaceuticals Made with Hydrogen: A Sustainable and Efficient Approach Using Flow Synthesis

open access: yesChemistry – A European Journal, EarlyView.
We demonstrate a sustainable strategy for pharmaceutical manufacturing by combining hydrogen, heterogeneous catalysis, and continuous flow synthesis. The development of novel catalysts and their application in a multi‐step synthesis of donepezil enabled a highly productive process with no intermediate purification.
Shū Kobayashi, Haruro Ishitani
wiley   +1 more source

Nonsteroidal Anti‐Inflammatory Drugs as Modulators of Cation Channels: Fenamates Repurposing in Channelopathies

open access: yesChemMedChem, EarlyView.
Beyond their established role as nonsteroidal anti‐inflammatory drugs (NSAIDs), fenamates (niflumic, flufenamic, mefenamic, meclofenamic, and tolfenamic acids) have recently been identified as modulators of cationic ion channels. This review highlights their differential effects on ion channel activity and explores their potential for repurposing in ...
Paola Laghetti   +4 more
wiley   +1 more source

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