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Current Understanding of Asthma Pathogenesis and Biomarkers
Asthma is a heterogeneous lung disease with variable phenotypes (clinical presentations) and distinctive endotypes (mechanisms). Over the last decade, considerable efforts have been made to dissect the cellular and molecular mechanisms of asthma ...
Nazia Habib, M. Pasha, D. Tang
semanticscholar +1 more source
Asthma remission: what is it and how can it be achieved?
Asthma treatment goals currently focus on symptom and exacerbation control rather than remission. Remission is not identical to cure, but is a step closer.
Dennis Thomas +3 more
semanticscholar +1 more source
Use of the complex of models of regression for analysis of the factors that determine the severity of bronchial asthma [PDF]
Background: According to an International Study of Asthma and Allergies in Childhood (ISAAC), the prevalence of asthma in children of 6-7 years old has increased by 10%, and at the age of 13-14 years by 16% over the last decade.
Kozhyna, Olga S., Pihnastyi, O. M.
core +1 more source
Concern has arisen about hypersensitivity reactions in patients with allergic reactions to drugs containing polyethylene glycol (PEG) or polysorbate 80 (PS80), excipients of currently available anti-SARS-CoV-2 mRNA vaccines.
Emanuele Nappi +12 more
doaj +1 more source
The blue one takes a battering why do young adults with asthma overuse bronchodilator inhalers? A qualitative study [PDF]
Objective: Overuse of short-acting bronchodilators is internationally recognised as a marker of poor asthma control, high healthcare use and increased risk of asthma death. Young adults with asthma commonly overuse short-acting bronchodilators. We sought
Cole, S, Griffiths, C, Seale, C
core +2 more sources
Dupilumab Efficacy and Safety in Moderate‐to‐Severe Uncontrolled Asthma
BACKGROUND Dupilumab is a fully human anti–interleukin‐4 receptor α monoclonal antibody that blocks both interleukin‐4 and interleukin‐13 signaling. We assessed its efficacy and safety in patients with uncontrolled asthma.
M. Castro +26 more
semanticscholar +1 more source
Predictive factors for moderate or severe exacerbations in asthma patients receiving outpatient care
Background Asthma exacerbations are important events that affect disease control, but predictive factors for severe or moderate exacerbations are not known. The objective was to study the predictive factors for moderate (ME) and severe (SE) exacerbations
Francisco Javier Álvarez Gutiérrez +5 more
doaj +1 more source
Patient and public involvement in research: from tokenistic box ticking to valued team members
Background Patient and public involvement (PPI) in research envisages a relationship built throughout the lifespan of a research project between academics, clinicians and PPI colleagues in order to inform, plan, execute and, in due course, disseminate ...
Tracy Jackson +8 more
doaj +1 more source
Vaccines for SAR-CoV-2 are the most effective preventive treatment able to reduce the risk of contracting the infection and experiencing worse outcomes whenever the infection is contracted.
Maria Rita Messina +11 more
doaj +1 more source
Allergy clinics in times of the SARS-CoV-2 pandemic: an integrated model
Background Almost the entire World is experiencing the Coronavirus-Disease-2019 (COVID-19) pandemic, responsible, at the end of May 2020, of more than five million people infected worldwide and about 350,000 deaths. In this context, a deep reorganization
Giacomo Malipiero +12 more
doaj +1 more source

