Results 21 to 30 of about 1,415,651 (391)

A Twin Study of Early-Childhood Asthma in Puerto Ricans [PDF]

, 2013
Background:The relative contributions of genetics and environment to asthma in Hispanics or to asthma in children younger than 3 years are not well understood.Objective:To examine the relative contributions of genetics and environment to early-childhood ...
Bunyavanich, S, Canino, G, Celedn, JC, Gillespie, NA, Lange, NE, Lasky-Su, J, Silberg, JL   +6 more
core   +13 more sources

The adherence to and utility of the Global Initiative for Chronic Obstructive Lung Disease guidelines for treating COPD among pulmonary specialists: a retrospective analysis

BMC Pulmonary Medicine, 2023
Background Despite the evidence-based guidelines promoted by the Global Initiative for Chronic Obstructive Lung Disease (GOLD), the overuse of prescription drugs to manage COPD, particularly inhaled corticosteroids (ICS), remains a persistent challenge ...
Fortune O. Alabi, Hadaya A. Alkhateeb, Mukudzeishe T. Zibanayi, Jica Garces, Kayla M. DeBarros, Pierina S. Benel Barletti, Kayla Garcia, Randall K. James   +7 more
doaj   +1 more source

Sex and gender in asthma

European Respiratory Review, 2021
Asthma is a heterogenous disease, and its prevalence and severity are different in males versus females through various ages. As children, boys have an increased prevalence of asthma.
Nowrin U. Chowdhury, V. Guntur, D. Newcomb, M. Wechsler   +3 more
semanticscholar   +1 more source

Spermidine and spermine exert protective effects within the lung

Pharmacology Research & Perspectives, 2021
Asthma is a heterologous disease that is influenced by complex interactions between multiple environmental exposures, metabolism, and host immunoregulatory processes. Specific metabolites are increasingly recognized to influence respiratory inflammation.
Marcin Wawrzyniak, David Groeger, Remo Frei, Ruth Ferstl, Paulina Wawrzyniak, Krzysztof Krawczyk, Benoit Pugin, Weronika Barcik, Patrick Westermann, Anita Dreher, Michael Scharl, Marek Jutel, Cezmi A. Akdis, Liam O`Mahony   +13 more
doaj   +1 more source

Monitoring asthma in childhood : Lung function, bronchial responsiveness and inflammation [PDF]

, 2015
Peer reviewedPublisher ...
ERS Task Force Monitoring Asthma in Children
core   +1 more source

International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods.

European Respiratory Journal, 1995
The aetiology of asthma and allergic disease remains poorly understood, despite considerable research. The International Study of Asthma and Allergies in Childhood (ISAAC), was founded to maximize the value of epidemiological research into asthma and ...
M. Asher, U. Keil, H. R. Anderson, R. Beasley, J. Crane, F. D. Martinez, E. Mitchell, N. Pearce, B. Sibbald, A. Stewart, D. Strachan, S. Weiland, H. Williams   +12 more
semanticscholar   +1 more source

COVID-19–related Genes in Sputum Cells in Asthma. Relationship to Demographic Features and Corticosteroids

American Journal of Respiratory and Critical Care Medicine, 2020
Rationale: Coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). ACE2 (angiotensin-converting enzyme 2), and TMPRSS2 (transmembrane protease serine 2) mediate viral infection of host cells.
M. Peters, S. Sajuthi, P. DeFord, S. Christenson, C. Rios, M. Montgomery, P. Woodruff, D. Mauger, S. Erzurum, M. Johansson, Loren C Denlinger, N. Jarjour, M. Castro, A. Hastie, W. Moore, V. Ortega, E. Bleecker, S. Wenzel, E. Israel, B. Levy, M. Seibold, J. Fahy   +21 more
semanticscholar   +1 more source

It takes a village: perceptions of Winnipeg parents, students, teachers and school staff regarding the impact of food allergy on school-age students and their families

Allergy, Asthma & Clinical Immunology, 2022
Background The entire school community contributes to the safety of students with food allergy. We sought to determine the food allergy perceptions and education needs of parents, students and school staff, with the goal of enhancing food allergy ...
Nancy Ross, Sandra Dalke, Shauna Filuk, Bev Kulbaba, Diane Marks, Jo-Anne St-Vincent, Elinor Simons   +6 more
doaj   +1 more source

Reslizumab in patients with inadequately controlled late-onset asthma and elevated blood eosinophils [PDF]

, 2017
INTRODUCTION: Asthma with adult onset and elevated blood eosinophils is a difficult-to-treat subgroup. This post hoc analysis evaluated reslizumab, an anti-interleukin-5 monoclonal antibody, in patients with late-onset eosinophilic asthma.
Brusselle, Guy, Germinaro, Matthew, Weiss, Sivan, Zangrilli, James   +3 more
core   +2 more sources

Dupilumab Efficacy and Safety in Moderate‐to‐Severe Uncontrolled Asthma

New England Journal of Medicine, 2018
BACKGROUND Dupilumab is a fully human anti–interleukin‐4 receptor α monoclonal antibody that blocks both interleukin‐4 and interleukin‐13 signaling. We assessed its efficacy and safety in patients with uncontrolled asthma.
M. Castro, J. Corren, I. Pavord, J. Maspero, S. Wenzel, K. Rabe, W. Busse, L. Ford, L. Sher, M. Fitzgerald, C. Katelaris, Y. Tohda, Bingzhi Zhang, H. Staudinger, G. Pirozzi, N. Amin, M. Ruddy, B. Akinlade, A. Khan, J. Chao, R. Martincova, N. Graham, J. Hamilton, B. Swanson, N. Stahl, G. Yancopoulos, A. Teper   +26 more
semanticscholar   +1 more source