Results 291 to 300 of about 1,522,848 (395)

Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma.

New England Journal of Medicine, 2014
E. Bel, S. Wenzel, P. Thompson, C. Prazma, O. Keene, S. Yancey, H. Ortega, I. Pavord   +7 more
semanticscholar   +1 more source

Pharmacokinetics and Bioequivalence of a Novel Extended‐Release Formulation of Methylphenidate Hydrochloride for Attention‐Deficit/Hyperactivity Disorder

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Extended‐release (ER) formulations of the stimulant methylphenidate are commonly used to treat attention‐deficit/hyperactivity disorder in both children and adults. Previous studies have shown that the clinical effectiveness of long‐acting methylphenidate formulations is closely tied to the drug's pharmacokinetic (PK) profile, highlighting the
Ann C. Childress, Ahmad AL‐Sabbagh, Jeffrey H. Newcorn   +2 more
wiley   +1 more source

Spirometry to manage asthma in children: study protocol for a randomised controlled trial (SPIROMAC). [PDF]

Trials
Bell V, Sergenson N, Cotton S, Emele CD, Thomas R, Aucott L, Forrest M, Gaillard EA, Kennington EJ, MacLennan G, Sinha I, Vadiveloo T, Scott NW, Turner S.   +13 more
europepmc   +1 more source

Type 2 inflammation in asthma — present in most, absent in many

Nature reviews. Immunology, 2014
J. Fahy
semanticscholar   +1 more source

Risk of Infections with SGLT2 Inhibitors Versus DPP4 Inhibitors: A Population‐Based Cohort Study Using Antibiotic Dispensing Data

Clinical Pharmacology &Therapeutics, EarlyView.
This study compared the number and cumulative dose of antibiotic dispensings among new users of sodium–glucose cotransporter‐2 (SGLT2) inhibitors and dipeptidyl peptidase‐4 (DPP4) inhibitors following hospital discharge in individuals with type 2 diabetes.
Maria J. Alfonso Arvez, George S. Q. Tan, Sam Wade, Zanfina Ademi, Jenni Ilomäki, J. Simon Bell   +5 more
wiley   +1 more source

Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction

Journal of Clinical Investigation, 2018
E. Dunican, B. Elicker, D. Gierada, S. Nagle, M. Schiebler, J. Newell, W. Raymond, M. Lachowicz-Scroggins, S. Di Maio, E. Hoffman, M. Castro, S. Fain, N. Jarjour, E. Israel, B. Levy, S. Erzurum, S. Wenzel, D. Meyers, E. Bleecker, B. Phillips, D. Mauger, Erin D. Gordon, P. Woodruff, M. Peters, J. Fahy   +24 more
semanticscholar   +1 more source

Clinical Trials With Pragmatic Elements: A Review of Use Cases and Real‐World Data Utilization

Clinical Pharmacology &Therapeutics, EarlyView.
Clinical trials with pragmatic elements can capture diverse patient populations, enable efficient follow‐up, and reflect routine clinical practices; yet there is limited understanding of their design features, characteristics, and use of real‐world data (RWD). Based on a targeted search of PubMed/EMBASE (Jan‐2016 to Jul‐2024), a review was conducted to
Le Su, Lei Chen, Seema Betigeri, Nancy Dreyer, Helga Gardarsdottir, Rachele Hendricks‐Sturrup, Mehmet Burcu   +6 more
wiley   +1 more source

Neutrophilic asthma may not be a distinct endotype. [PDF]

ERJ Open Res
Bhalla A, Sehmi R, Nair P, Mukherjee M.
europepmc   +1 more source

THE INCIDENCE OF ALLERGY AND ASTHMA IN A GROUP DEVELOPING POST-OPERATIVE ATELECTASIS

, 1930
Harry B. Wilmer, Herbert M. Cobe, Walter Estell Lee   +2 more
openalex   +2 more sources

TFE3‐Rearranged PEComa(‐Like Neoplasm) of the Chest Wall Diagnosed by Fine‐Needle Aspiration: A Case Report

Diagnostic Cytopathology, EarlyView.
ABSTRACT We report a rare TFE3‐rearranged perivascular epithelioid cell tumor (PEComa) of the parasternal chest wall diagnosed preoperatively by fine‐needle aspiration (FNA) cytology. The smears and cell block showed epithelioid cells with clear to granular cytoplasm and prominent nucleoli.
Shah Dev, Matthew Miller, Tom Hu, Cindy McGrath, Roseann I. Wu   +4 more
wiley   +1 more source