Results 51 to 60 of about 1,415,651 (391)

Diagnosis and management of eosinophilic asthma: a US perspective. [PDF]

, 2014
Eosinophilic asthma is now recognized as an important subphenotype of asthma based on the pattern of inflammatory cellular infiltrate in the airway. Eosinophilic asthma can be associated with increased asthma severity, atopy, late-onset disease, and ...
Doherty, Taylor A, Walford, Hannah H
core   +1 more source

Cytomegalovirus serology in young to mid‐adult life and decline of lung function

The Clinical Respiratory Journal, 2023
Introduction Cytomegalovirus (CMV) seropositivity has been recently linked to severity and progression of asthma, cystic fibrosis, and chronic obstructive pulmonary disease (COPD). To date, no longitudinal study has addressed the relation of CMV serology
Raffaella Nenna, Jing Zhai, Amber Spangenberg, Duane L. Sherrill, Fernando D. Martinez, Marilyn Halonen, Stefano Guerra   +6 more
doaj   +1 more source

Prevalence of asthma symptoms in Golestan schoolchildren aged 6–7 and 13–14 years in Northeast Iran [PDF]

, 2016
Asthma is the most common chronic disease among children, and its incidences are often imminent among elementary schoolchildren. This study aimed to examine the prevalence of asthma symptoms in Golestan schoolchildren aged 6–7 and 13–14 years in ...
Bazrafshan, B., Khodadost, M., Mehravar, F., Rafiee, S.   +3 more
core   +1 more source

Efficacy and Safety of Dupilumab in Glucocorticoid‐Dependent Severe Asthma

New England Journal of Medicine, 2018
BACKGROUND Dupilumab is a fully human anti–interleukin‐4 receptor α monoclonal antibody that blocks both interleukin‐4 and interleukin‐13 signaling. Its effectiveness in reducing oral glucocorticoid use in patients with severe asthma while maintaining ...
K. Rabe, Parameswaran Nair, G. Brusselle, J. Maspero, M. Castro, L. Sher, Hongjie Zhu, J. Hamilton, B. Swanson, A. Khan, J. Chao, H. Staudinger, G. Pirozzi, C. Antoni, N. Amin, M. Ruddy, B. Akinlade, N. Graham, N. Stahl, G. Yancopoulos, A. Teper   +20 more
semanticscholar   +1 more source

Evaluation of Swab-Seq as a scalable, sensitive assay for community surveillance of SARS-CoV-2 infection

Scientific Reports, 2022
The ongoing SARS-CoV-2 pandemic and subsequent demand for viral testing has led to issues in scaling diagnostic lab efforts and in securing basic supplies for collection and processing of samples. This has motivated efforts by the scientific community to
HyunJin Kang, Sheilah Allison, Amber Spangenberg, Tara Carr, Ryan Sprissler, Marilyn Halonen, Darren A. Cusanovich   +6 more
doaj   +1 more source

House Dust Mite and Cat Dander Extract Induce Asthma-Like Histopathology with an Increase of Mucosal Mast Cells in a Guinea Pig Model

Journal of Immunology Research, 2023
Background. Asthma is a chronic inflammatory disease with structural changes in the lungs defined as airway remodelling. Mast cell responses are important in asthma as they, upon activation, release mediators inducing bronchoconstriction, inflammatory ...
Patricia Ramos-Ramírez, Jielu Liu, Sofia Mogren, Joshua Gregory, Malin Noreby, Anne Petrén, Ying Lei, Henric Olsson, Marianne van Hage, Jukka Kervinen, Lars Hellman, Cecilia Andersson, Gunnar Nilsson, Mikael Adner   +13 more
doaj   +1 more source

Management of severe asthma: a European Respiratory Society/American Thoracic Society guideline

European Respiratory Journal, 2019
This document provides clinical recommendations for the management of severe asthma. Comprehensive evidence syntheses, including meta-analyses, were performed to summarise all available evidence relevant to the European Respiratory Society/American ...
F. Holguin, J. Cardet, K. Chung, S. Diver, D. S. Ferreira, A. Fitzpatrick, M. Gaga, Liz Kellermeyer, S. Khurana, S. Knight, V. McDonald, R. Morgan, V. Ortega, D. Rigau, P. Subbarao, T. Tonia, I. Adcock, E. Bleecker, C. Brightling, L. Boulet, M. Cabana, M. Castro, P. Chanez, A. Custovic, R. Djukanović, U. Frey, B. Frankemölle, P. Gibson, D. Hamerlijnck, N. Jarjour, S. Konno, Huahao Shen, C. Vitary, A. Bush   +33 more
semanticscholar   +1 more source

A 5-year Study of Systemic Reactions Using both Shared and Patient-Specific Vaccines

Allergy & Rhinology, 2013
The safety of shared specific vaccines (SSVs) has been questioned by some experts. The purpose of this study was to evaluate the safety of SSVs. Details of systemic allergic reactions after subcutaneous immunotherapy injections were captured on a ...
Julian Melamed M.D., Ami Mehra M.D., Angela Ahuja-Malik M.D.   +2 more
doaj   +1 more source

The association of exhaled nitric oxide with air pollutants in young infants of asthmatic mothers

Environmental Health, 2023
Background Exhaled nitric oxide is a marker of airway inflammation. Air pollution induces airway inflammation and oxidative stress. Little is known about the impact of air pollution on exhaled nitric oxide in young infants. Methods The Breathing for Life
Elizabeth Percival, Adam M. Collison, Carla Rebeca da Silva Sena, Ediane De Queiroz Andrade, Patricia De Gouveia Belinelo, Gabriela Martins Costa Gomes, Christopher Oldmeadow, Vanessa E. Murphy, Peter G. Gibson, Wilfried Karmaus, Joerg Mattes   +10 more
doaj   +1 more source

Feasibility of sustained response through long-term dosing in food allergy immunotherapy

Allergy, Asthma & Clinical Immunology, 2017
Background Clinical trials using oral immunotherapy (OIT) for the treatment of food allergies have shown promising results. We previously demonstrated the feasibility of desensitization for up to 5 food allergens simultaneously through OIT.
Sandra Andorf, Monali Manohar, Tina Dominguez, Whitney Block, Dana Tupa, Rohun A. Kshirsagar, Vanitha Sampath, R. Sharon Chinthrajah, Kari C. Nadeau   +8 more
doaj   +1 more source