Results 61 to 70 of about 1,415,651 (391)

Urinary Eosinophil-derived Neurotoxin Concentrations in Patients with Atopic Dermatitis: A Useful Clinical Marker for Disease Activity

Allergology International, 2007
Background: It has been reported that measurements of eosinophil-derived neurotoxin (EDN) may be useful for identifying eosinophil activities in allergic diseases including atopic dermatitis.
Tomoko Goto, Junichiro Morioka, Hiroaki Inamura, Megumi Yano, Kazumi Kodaira, Yasushi Igarashi, Shyuzo Abe, Motohiro Kurosawa   +7 more
doaj   +1 more source

Observational long-term follow-up study of rapid food oral immunotherapy with omalizumab

Allergy, Asthma & Clinical Immunology, 2017
Background A number of clinical studies focused on treating a single food allergy through oral immunotherapy (OIT) with adjunctive omalizumab treatment have been published.
Sandra Andorf, Monali Manohar, Tina Dominguez, Whitney Block, Dana Tupa, Rohun A. Kshirsagar, Vanitha Sampath, R. Sharon Chinthrajah, Kari C. Nadeau   +8 more
doaj   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

Effectiveness of a Telephone‐Delivered Walk With Ease Program on Arthritis‐Related Symptoms, Function, and Activity: A Randomized Trial

Arthritis Care &Research, EarlyView.
Objective Walk With Ease (WWE) is a six‐week arthritis‐appropriate evidence‐based physical activity program traditionally offered in a face‐to‐face format. Because many populations encounter participation barriers to in‐person programs, WWE was modified for telephone delivery (WWE‐T).
Christine A. Pellegrini, Sara Wilcox, Yesil Kim, Scott Jamieson, Katherine DeVivo, Daniel Heidtke   +5 more
wiley   +1 more source

Fish oil and vitamin D in pregnancy for the prevention of early childhood asthma: study protocol for two double-blinded, randomised controlled trials

BMJ Open
Introduction Previous randomised controlled trials (RCTs) have indicated a protective role of pregnancy supplementation with fish oil and high-dose vitamin D, respectively, on offspring asthma, infections and several other disorders in early childhood ...
Klaus Bønnelykke, Jakob Stokholm, Rebecca Vinding, Bo Chawes, Julie Nyholm Kyvsgaard, Ulrik Ralfkiaer, Marianne Mikkelsen, Nicklas Brustad, Sarah Brandt, Nilo Vahman   +9 more
doaj   +1 more source

Microbiome and asthma

Asthma Research and Practice, 2018
The mucosal immune system is in constant communication with the vast diversity of microbes present on body surfaces. The discovery of novel molecular mechanisms, which mediate host-microbe communication, have highlighted the important roles played by ...
Milena Sokolowska, Remo Frei, Nonhlanhla Lunjani, Cezmi A. Akdis, Liam O’Mahony   +4 more
doaj   +1 more source

Rhinovirus-induced epithelial RIG-I inflammasome suppresses antiviral immunity and promotes inflammation in asthma and COVID-19

Nature Communications, 2023
Rhinoviruses and allergens, such as house dust mite are major agents responsible for asthma exacerbations. The influence of pre-existing airway inflammation on the infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is largely ...
Urszula Radzikowska, Andrzej Eljaszewicz, Ge Tan, Nino Stocker, Anja Heider, Patrick Westermann, Silvio Steiner, Anita Dreher, Paulina Wawrzyniak, Beate Rückert, Juan Rodriguez-Coira, Damir Zhakparov, Mengting Huang, Bogdan Jakiela, Marek Sanak, Marcin Moniuszko, Liam O’Mahony, Marek Jutel, Tatiana Kebadze, David J. Jackson, Michael R. Edwards, Volker Thiel, Sebastian L. Johnston, Cezmi A. Akdis, Milena Sokolowska   +24 more
doaj   +1 more source

Avoidable Hospitalizations in Persons With Rheumatoid Arthritis: A Population‐Based Study Using Administrative Data

Arthritis Care &Research, EarlyView.
Objective We estimated incidence rates of avoidable hospitalizations by persons with rheumatoid arthritis (RA) relative to the general population. Methods We identified individuals meeting a validated case definition for RA based on International Classification of Diseases, Ninth Revision, Clinical Modification (ICD‐9‐CM) and ICD‐10‐CA codes in years ...
Dani G. Contreras, Claire E. H. Barber, J. Antonio Aviña‐Zubieta, Hude Quan, Seungwon Lee, James A. King, Cheryl Barnabe   +6 more
wiley   +1 more source

Disease-associated KIF3A variants alter gene methylation and expression impacting skin barrier and atopic dermatitis risk

Nature Communications, 2020
Genetic variants in KIF3A are associated with atopic dermatitis (AD). Here, the authors identify two AD-risk alleles that show high methylation resulting in lower KIF3A expression.
Mariana L. Stevens, Zhonghua Zhang, Elisabet Johansson, Samriddha Ray, Amrita Jagpal, Brandy P. Ruff, Arjun Kothari, Hua He, Lisa J. Martin, Hong Ji, Kathryn Wikenheiser-Brokamp, Matthew T. Weirauch, Dorothy M. Supp, Jocelyn M. Biagini Myers, Gurjit K. Khurana Hershey   +14 more
doaj   +1 more source

Selective Reduction Laser Sintering: A New Strategy for NO2 Gas Detection Based on In2O3 Nanoparticles

Advanced Functional Materials, EarlyView.
This research utilizes selective reduction laser sintering (SRLS) to engineer In2O3 NPs for flexible NO2 sensors. The introduction of oxygen vacancy defects enhances sensor performance, offering excellent responsiveness, rapid response/recovery, superior selectivity, low detection limit, and long‐term stability.
Shaogang Wang, Chunjian Tan, Qihang Zong, Shizhen Li, Chenshan Gao, Huiru Yang, Qianming Huang, Paddy French, Huaiyu Ye   +8 more
wiley   +1 more source