Results 71 to 80 of about 1,522,848 (395)

Asthma

Allergy, Asthma & Clinical Immunology
Abstract Asthma is one of the most common respiratory disorders in Canada, however, many Canadians with asthma remain poorly controlled. In most patients, control can be achieved through appropriate therapy, including: inhaled corticosteroids (ICS), combination ICS/long-acting beta2-agonists (LABA), “triple therapy” with ICS/LABA/long-acting ...
Andrew O’Keefe, Lori Connors, Ling Ling, Harold Kim   +3 more
openaire   +3 more sources

Adipokines and Associations with Incident Osteoporotic Fracture in Patients with Rheumatoid Arthritis

Arthritis Care &Research, Accepted Article.
Purpose We assessed whether circulating adipokines are associated with incident fractures in patients with rheumatoid arthritis (RA). Methods Three adipokines (adiponectin, leptin, fibroblast growth factor [FGF]‐21) were measured using banked enrollment serum from participants in a longitudinal RA cohort.
Joshua F. Baker, Bryant R. England, Michael D. George, Hannah Brubeck, Brian Sauer, Aleksander Lenert, Punyasha Roul, Geoffrey M. Thiele, Ted R. Mikuls, Katherine D. Wysham   +9 more
wiley   +1 more source

Profiling of H3K27Ac Reveals the Influence of Asthma on the Epigenome of the Airway Epithelium

Frontiers in Genetics, 2020
BackgroundAsthma is a chronic airway disease driven by complex genetic–environmental interactions. The role of epigenetic modifications in bronchial epithelial cells (BECs) in asthma is poorly understood.MethodsWe piloted genome-wide profiling of the ...
Peter McErlean, Peter McErlean, Audrey Kelly, Audrey Kelly, Jaideep Dhariwal, Jaideep Dhariwal, Max Kirtland, Max Kirtland, Julie Watson, Julie Watson, Ismael Ranz, Ismael Ranz, Janet Smith, Alka Saxena, David J. Cousins, David J. Cousins, Antoon Van Oosterhout, Roberto Solari, Roberto Solari, Michael R. Edwards, Michael R. Edwards, Sebastian L. Johnston, Sebastian L. Johnston, Paul Lavender, Paul Lavender   +24 more
doaj   +1 more source

Latino Asthma Epidemic [PDF]

, 2009
Chicago is known for many things, our great food and architecture. Unfortunately, we are also known for being an epi-center for asthma. We lead the Nation in asthma deaths, emergency room visits and hospitalizations.

core  

Perceptions about asymptomatic hyperuricemia and views about urate‐lowering therapy in people with asymptomatic hyperuricemia

Arthritis Care &Research, Accepted Article.
Background/Aims Asymptomatic hyperuricemia is a precursor of gout and is also associated with cardiovascular disease and chronic kidney disease. The aim of this study was to understand perceptions about asymptomatic hyperuricemia and views about urate‐lowering therapy in people with asymptomatic hyperuricemia.
Nicola Dalbeth, Sarah Stewart, Gregory D Gamble, Borislav Mihov, Lisa K Stamp, Janine Haslett, William J Taylor, Tony R Merriman, Adwoa Dansoa Tabi‐Amponsah, Anne Horne, Tuhina Neogi, Tristan Pascart, Mariano Andrés, Maria‐Luisa Peral‐Garrido, Eleonora Norkuviene, Janitzia Vazquez Mellado, Till Uhlig, Mingshu Sun, Changgui Li, Keith J Petrie   +19 more
wiley   +1 more source

Disease-associated KIF3A variants alter gene methylation and expression impacting skin barrier and atopic dermatitis risk

Nature Communications, 2020
Genetic variants in KIF3A are associated with atopic dermatitis (AD). Here, the authors identify two AD-risk alleles that show high methylation resulting in lower KIF3A expression.
Mariana L. Stevens, Zhonghua Zhang, Elisabet Johansson, Samriddha Ray, Amrita Jagpal, Brandy P. Ruff, Arjun Kothari, Hua He, Lisa J. Martin, Hong Ji, Kathryn Wikenheiser-Brokamp, Matthew T. Weirauch, Dorothy M. Supp, Jocelyn M. Biagini Myers, Gurjit K. Khurana Hershey   +14 more
doaj   +1 more source

The effect of foot orthoses on midfoot pain and the volume of bone marrow lesions in the midfoot: a randomized mechanism of action study

Arthritis Care &Research, Accepted Article.
Objective Foot orthoses are thought to improve pain by potentially modifying internal mechanical forces. To test this, we explored whether foot orthoses can modify patterns of bone marrow lesions (BMLs) in people with midfoot pain. Methods Forty‐two people were recruited with midfoot pain and MRI‐confirmed midfoot BMLs.
Jill Halstead, Anne‐Maree Keenan, Philip G. Conaghan, Dennis McGonagle, Anthony C. Redmond   +4 more
wiley   +1 more source

Occupational Asthma or Work-Related Exacerbation of Asthma [PDF]

, 2019
[Excerpt] Occupational asthma is asthma due to work exposures. It can be caused by a specific workplace agent with a specific immune system response – the agent is called a sensitizer.
Brown, Nellie J
core   +1 more source

Investigating the association between obesity and asthma in 6- to 8-year-old Saudi children:a matched case-control study [PDF]

, 2014
Background: Previous studies have demonstrated an association between obesity and asthma, but there remains considerable uncertainty about whether this reflects an underlying causal relationship.
A Bener, A Bereket, A Deesomchok, A Sood, AA Mamun, AB Hill, C Anandan, CA Camargo Jr, CAJ Camargo, CL Ogden, D Sole, DS Freedman, HR Anderson, IA Janahi, JA Castro-Rodriguez, JJ Reilly, JL Clausen, JL Santos, JM Tanner, JV Durnin, JÖ Magnusson, KG Tantisira, KM Baker, L Trasande, LG Hersoug, M Badran, M Nahhas, M Stumvoll, M Weiss, MR Miller, N Beydon, N Hatipoglu, N Scopinaro, N Vangeepuram, P Bustos, PM Matricardi, RB Noal, RJ Hancox, S Kannan, SA Shore, SA Shore, SH Arshad, SO Shaheen, ST Weiss, ST Weiss, TL Guidotti, TS Hallstrand, TZ Kajbaf, V Mishra, VE Cassol, W Nystad, Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC, Y Mohammad   +52 more
core   +2 more sources

Asthma and asthma-like disorders

Respiratory Medicine, 1999
Bronchial asthma is defined as a chronic inflammatory disease resulting in a reversible and variable bronchial obstruction. For the clinical diagnosis of the disease there are some key indicators but as there is no 'gold standard' a correct diagnosis will sometimes not be obtained.
openaire   +2 more sources