Results 151 to 160 of about 88,327 (313)

PIK3R1 mutations in individuals with insulin resistance or growth retardation: Case series and in silico functional analysis

open access: yesJournal of Diabetes Investigation, EarlyView.
We present a report on SHORT syndrome caused by PIK3R1 mutations, including findings from in silico analysis. Our results demonstrate that these mutations impair the ability of p85α to interact with phosphopeptides. ABSTRACT Aims/Introduction Phosphatidylinositol 3‐kinase (PI3K) plays a key role in insulin signaling, and mutations in PIK3R1, which ...
Tomofumi Takayoshi   +15 more
wiley   +1 more source

Efficacy of patching combined with action video games in amblyopic children aged 4–10 years: A randomised clinical trial

open access: yesOphthalmic and Physiological Optics, EarlyView.
Abstract Purpose To determine the impact of using child‐friendly action video games combined with monocular occlusion for the treatment of children with amblyopia compared with occlusion alone. Methods Twenty‐eight children aged 4–10 years (mean age: 5.80 ± 1.54 years) with anisometropic and/or strabismic amblyopia were included.
Laura Asensio‐Jurado   +4 more
wiley   +1 more source

Frequency of retinal findings after 8 years in the Bifocal Lenses in Nearsighted Kids (BLINK) Study

open access: yesOphthalmic and Physiological Optics, EarlyView.
Abstract Purpose The purpose of the study is to report the frequency of retinal findings in myopic children and determine the association with the amount of myopia or axial length. Design The BLINK study was a myopia control, multi‐centre randomised clinical trial following myopic children with multifocal soft contact lenses. Participants Children aged
Krystal L. Schulle   +44 more
wiley   +1 more source

Compensatory Interactions between Corneal and Internal Astigmatism despite Lifestyle Changes

open access: yesChildren
This study explores whether children’s refractive errors and visual behaviors reverted to pre-COVID-19 levels a year after normal schooling resumed in Hong Kong as well as the impact of corneal and internal astigmatism on refractive astigmatism ...
Yuanyuan Liang   +3 more
doaj   +1 more source

Deciphering the performance of different surface models for corneal topography

open access: yesOphthalmic and Physiological Optics, EarlyView.
Abstract Purpose To study the performance of different corneal surface models to be used for ray tracing. Models based on geometric surfaces and polynomial fits were compared and the differences discussed. Methods For this simulation study, five characteristic generic surface configurations were generated: (A) perfect biconic, (B) decentred biconic ...
Achim Langenbucher   +4 more
wiley   +1 more source

Impact of central corneal astigmatism on postoperative visual outcomes in patients undergoing trifocal intraocular lens implantation

open access: yesBMC Ophthalmology
Background To investigate the impact of central corneal astigmatism on postoperative visual outcomes in patients with trifocal intraocular lens (IOL) implantation.
Lan Wang   +5 more
doaj   +1 more source

Three‐year myopia management efficacy of extended depth of focus soft contact lenses (MYLO) in Caucasian children

open access: yesOphthalmic and Physiological Optics, EarlyView.
Abstract Purpose To evaluate the progression of myopia as assessed by changes in axial length (AL) and spherical equivalent (SE) in Caucasian children wearing extended depth of focus soft contact lenses (CL) compared with distance single‐vision spectacles after 3 years.
Sergio Díaz‐Gómez   +4 more
wiley   +1 more source

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