Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source
What does a bacterial genome sequence represent? Mis-assignment of MAFF 303099 to the genospecies Mesorhizobium loti [PDF]
Li, F. +3 more
core +1 more source
The Role of Dice in the Emergence of the Probability Calculus
Summary The early development of the probability calculus was clearly influenced by the roll of dice. However, while dice have been cast since time immemorial, documented calculations on the frequency of various dice throws date back only to the mid‐13th century.
David R. Bellhouse, Christian Genest
wiley +1 more source
ABSTRACT Aims To identify and synthesise nursing interventions directed at family caregivers of patients with end‐stage renal disease undergoing haemodialysis. Design A convergent‐integrated mixed‐methods systematic review. Data Sources A comprehensive search was conducted in EBSCOHost databases (Academic Search Complete, CINAHL Complete, MEDLINE with ...
Hélder Araújo +4 more
wiley +1 more source
Role of BacA in Lipopolysaccharide Synthesis, Peptide Transport, and Nodulation by \u3cem\u3eRhizobium\u3c/em\u3e sp. Strain NGR234 [PDF]
BacA of Sinorhizobium meliloti plays an essential role in the establishment of nitrogen-fixing symbioses with Medicago plants, where it is involved in peptide import and in the addition of very-long-chain fatty acids (VLCFA) to lipid A of ...
Ardissone, Silvia +7 more
core +1 more source
This study investigated how variations in the shape of the astragalus affect tarsal joint behavior, using CT scans. In artiodactyls with a double‐pulley astragalus, the calcaneus shifted plantarly during plantarflexion. This suggests the movement increases hindlimb functional length and contributes to enhanced running speed.
Sei‐ichiro Takeda +3 more
wiley +1 more source
Postcranial anatomy of the Miocene hippopotamoids of Toros‐Menalla, Chad
We establish a framework for the identification of postcranial remains in hippopotamoids by describing and comparing for the first time two late Miocene hippopotamoids from Toros‐Menalla, Chad (Hexaprotodon garyam, an early hippopotamid, and Libycosaurus bahri, the last African anthracothere) with the common hippopotamus.
Lorenzo Scribano +4 more
wiley +1 more source
Microanatomical features of bovids long bones: What are the effects of mass and habitat?
This study provides the first qualitative and quantitative exploration of inter‐bones and interspecific variations in the microanatomy of long bones in bovids in response to significant changes in body mass and habitat. Abstract Bovids are a valuable group for studying limb long bone adaptations due to differences in size and the environment that the ...
Morgan Proust +2 more
wiley +1 more source
Functional morphology of trabecular bone in the calcaneus of African apes
Pan exhibits significantly higher calcaneal tuberosity trabecular thickness (Tb.Th) and bone volume fraction (BV/TV) than Gorilla, potentially reflecting higher triceps surae forces for vertical climbing. Both taxa have significantly higher Tb.Th and BV/TV in the anterior calcaneus; the difference is exaggerated in Gorilla, potentially reflecting ...
Christine M. Harper, Biren A. Patel
wiley +1 more source
Energy Evaluation and Economic Impact Analysis of Green Roofs Applied to a Pilot Region in Aegean Coast of Turkey [PDF]
This paper examines the energy savings, environmental benefits, and economic impact of green roof systems applied to a “micro” region in Western Turkey.
Ayla Ogus Binatli +4 more
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