Results 211 to 220 of about 194,703 (370)
A self‐propelled nanomedicine delivery system forms DMCU nanoparticles in the bladder via in situ polymerization of dopamine hydrochloride, Mn2+, cGAMP, and urease. The urease‐driven propulsion enhances retention and drug delivery. These nanoparticles activate the STING pathway, stimulating dendritic cells and T cells to boost anti‐bladder cancer ...
Lei Peng+9 more
wiley +1 more source
Effect of monensin on deoxyglucose uptake in cultured astrocytes: energy metabolism is coupled to sodium entry [PDF]
Paul Yarowsky+3 more
openalex +1 more source
Microenvironmental Modulation for Therapeutic Efficacy of Extracellular Vesicles
Recent studies highlighted the heterogeneity of EVs and the influence of microenvironmental signals on their therapeutic efficacy. This review offers a comprehensive overview of strategies and mechanisms to optimize the therapeutic efficacy of EVs through physical, biochemical, and mechanical modulation.
Bilu Xiang+4 more
wiley +1 more source
TGIF1 overexpression promotes glioma progression and worsens patient prognosis
This study is the first to comprehensively analyze and reveal TGIF1, as a new oncogene, is closely related to the malignancy‐related phenotype of glioma, and that TGIF1 could be an independent risk factor for poor prognosis of glioma, which is expected to become a new target for individualized treatment of glioma patients.
Baoya Wang+5 more
wiley +1 more source
Potassium modulation of methionine uptake in astrocytes in vitro [PDF]
C. J. Cummins+2 more
openalex +1 more source
This study presents a novel approach for intraoperative identification of the IDH1 genotype in glioma patients using a surface‐enhanced Raman scattering (SERS) probe to measure glutathione and hydrogen peroxide. By integrating AI‐driven deep learning algorithms, the method achieves rapid and accurate genotype differentiation, offering the potential to ...
Hang Yin+14 more
wiley +1 more source
Exosomes and their roles in the chemoresistance of pancreatic cancer
Despite the development of multiple promising chemotherapeutic agents as recommended first‐line treatment for PC, the therapeutic efficacy is largely limited by unwanted drug resistance.Exploring the relation between exosomes and chemoresistance may be conducive to understanding molecular mechanisms and taking effective measures to reduce the ...
Yubin Pan+4 more
wiley +1 more source
332 IN VITRO SYNTHESIS AND SECRETION OF A NERVE GROWTH FACTOR (NGF) BY NEONATAL MOUSE ASTROCYTES [PDF]
Morton E. Weichsel+2 more
openalex +1 more source
Fluorescence measurement of changes in intracellular calcium induced by excitatory amino acids in cultured cortical astrocytes [PDF]
Jensen Am, SY Chiu
openalex +1 more source