Results 221 to 230 of about 283,599 (345)

Obesity-induced astrocyte dysfunction impairs heterosynaptic plasticity in the orbitofrontal cortex [PDF]

, 2020
Benjamin K. Lau, Ciarán Murphy Royal, Manpreet Kaur, Min Qiao, Jaideep S. Bains, Grant R. Gordon, Stephanie L Borgland, Benjamin K. Lau, Ciarán Murphy Royal, Manpreet Kaur, Min Qiao, Jaideep S. Bains, Grant R. Gordon, Stephanie L Borgland   +13 more
openalex   +1 more source

Mechanical Environment Afforded by Engineered Hydrogel Critically Regulates Survival of Neural Stem Cells Transplanted in the Injured Spinal Cord via Piezo1‐Mediated Mechanotransduction

Advanced Science, EarlyView.
Neural stem cell transplantation shows promise for spinal cord repair, but poor graft survival limits therapeutic efficacy. This study demonstrates that increasing hydrogel stiffness from 10% to 16% concentration significantly enhances transplanted neural stem cell survival through Piezo1‐mediated mechanotransduction, revealing mechanical properties as
Hee Hwan Park, Yurim Kim, Byeong Seong Jang, Simay Genişcan, Dong Hoon Hwang, Yeojin Seo, Seung‐Ah Jee, Hyo Gyeong Seo, Hyung Soon Kim, Ariandokht Einisadr, Ho‐Jeong Kim, Seolhee Lee, Sangwoo Kwon, Kyung Sook Kim, Kang In Lee, Jae Young Lee, Joo Min Park, Young‐Min Kim, Soo‐Chang Song, Byung Gon Kim   +19 more
wiley   +1 more source

Lipid droplets in astrocytes: Key organelles for CNS homeostasis and disease (Review). [PDF]

Int J Mol Med
Wang Y, Wang B, Hou J, Huo X, Liu C, Guan R, Chen H, Zhou Y, Zhang J, Zhuang C, Zou Y.   +10 more
europepmc   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source

Astrocyte properties in cetacean cortices. [PDF]

Physiol Rep
Venkatesh A, McClain AM, Le-Bert CR, Musser WB, Ridgway SH.   +4 more
europepmc   +1 more source

Coronavirus induction of class I major histocompatibility complex expression in murine astrocytes is virus strain specific. [PDF]

, 1994
Wendy Gilmore, Jorge Correale, Leslie P. Weiner   +2 more
openalex   +1 more source

Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation.

Cell Metabolism, 2011
M. Bélanger, I. Allaman, P. Magistretti
semanticscholar   +1 more source

Iron Overload Mediates the Differential Cell Fate of Astrocytes from Neurons and Its Regulatory Mechanisms in Ischemic Stroke

Advanced Science, EarlyView.
Upon ischemia/reperfusion‐induced iron overload condition, neurons and astrocytes exhibit similar oxidative stress changes but opposite alterations in endogenous antioxidant defense mechanisms, leading to divergent ferroptotic outcomes. The iron deposition and neuronal loss are increased within the perilesional cortex of stroke patients ...
Yi Guo, Yue Wang, Yong Ni, Bin Bo, Jinzhi He, Yongming Zhu, Aiping Qin, Xianyong Zhou, Huaping Du, Yuan Liu, Tianyao Wang, Yudu Li, Yibo Zhao, Zengai Chen, Zhipei Liang, Yao Li, Yuan Xu, Huiling Zhang   +17 more
wiley   +1 more source

Inhibition of astrocyte BMP signaling alleviates neuroinflammation in experimental models of Parkinson's disease. [PDF]

Cell Death Discov
Li Y, Li Y, Hao J, Wang W, Su Z, Tian X, Wang H, Liu Q, Gao J, Geng D, Wang L.   +10 more
europepmc   +1 more source

CARD9 Conveys Pancreatic Islet Sympathetic Nervous β2 Signals to Reshape Macrophage Creatine Metabolism in Type 1 Diabetes

Advanced Science, EarlyView.
This study identifies CARD9 as a key mediator linking sympathetic β2‐adrenergic receptor signaling to macrophage creatine metabolism, inflammatory polarization, and neuronal integrity. Loss of β2‐AR‐PKA‐CREB1‐CARD9 signaling in macrophages reduces creatine uptake, promotes pro‐inflammatory macrophage activation, and drives sympathetic axon ferroptosis.
Huimin Yuan, Senlin Li, Shuai Liu, Hong Zhou, Yue Xu, Wenhui Li, Mengxuan Wang, Mengheng Wang, Mengzhu Zheng, Wenxi Shi, Xin Li, Yiting Feng, Ming Xiang   +12 more
wiley   +1 more source