Results 261 to 270 of about 283,599 (345)

Nucleus basalis-enabled stimulus-specific plasticity in the visual cortex is mediated by astrocytes [PDF]

, 2012
Naiyan Chen, Hiroki Sugihara, Jitendra Sharma, Gertrudis Perea, Jeremy Petravicz, Chuong Le, Mriganka Sur   +6 more
openalex   +1 more source

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

Advanced Science, EarlyView.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang, Yanran Zhang, Jialin Si, Honghui Mao, Feng He, Jin Ning, Guaiguai Ma, Xiaohua Chen, Haoxiang Xiao, Yuanyuan Zhu, Haifeng Zhang, Yifan Lu, Qian Liu, Meng Nian, Shiquan Sun, Shibin Yu, Shengxi Wu, Ze Fan, Zuolin Jin, Jing Huang   +19 more
wiley   +1 more source

Aging in mice alters regionally enriched striatal astrocytes. [PDF]

Nat Commun
Linker KE, Duran-Laforet V, Ollivier M, Yu X, Schafer DP, Khakh BS.   +5 more
europepmc   +1 more source

Reduced cAMP, Akt Activation and p65-c-Rel Dimerization: Mechanisms Involved in the Protective Effects of mGluR3 Agonists in Cultured Astrocytes

, 2011
Daniela Durand, Lila Carniglia, Carla Caruso, Mercedes Lasaga   +3 more
openalex   +2 more sources

Therapeutic Reprogramming of Glioblastoma Phenotypic States Using Multifunctional Heparin Nanoparticles

Advanced Science, EarlyView.
This study presents heparin‐derived nanoparticles (HP‐NPs) as a novel precision medicine platform that combines therapeutic and delivery functions. HP‐NPs target drug‐resistant glioblastoma stem cells, reprogramming them into a drug‐sensitive phenotype and significantly reducing tumor progression.
Vadim Le Joncour, Austin D. Evans, Camilla Karoliina Bergström, Vignesh Kumar Rangasami, Sumanta Samanta, Nithiyanandan Krishnan, Yuji Teramura, Bo Nilsson, Patricia Hedenqvist, Elin Manell, Jons Hilborn, Marianne‐Jensen Waern, Oommen P. Varghese, Pirjo Laakkonen, Oommen P. Oommen   +14 more
wiley   +1 more source

Disulfiram Prevents Blood-Brain Barrier Disruption in Epileptic Mice by Inhibiting Astrocyte Pyroptosis to Improve Seizure Activity. [PDF]

Mol Neurobiol
Zhang M, Zhao L, Chen S, Huang W, Jin X, Xu H.   +5 more
europepmc   +1 more source

Stain-free subcellular-resolution astrocyte imaging using third-harmonic generation

, 2019
M. S. Pochechuev, A. А. Lanin, Ilya V. Kelmanson, Dmitry S. Bilan, Daria A. Kotova, Artem S. Chebotarev, Victor Tarabykin, A. B. Fedotov, Vsevolod V. Belousov, А. М. Желтиков   +9 more
openalex   +2 more sources

Refractory Status Epilepticus and Therapeutic Uncertainties: a Comprehensive Review on Targeting Neuroinflammation and Rationale for Developing a Platform Trial

Advanced Science, EarlyView.
Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera, Suneesh Thilak, Asha Patel, Prashant Nasa, Zubair Ahmed, Lorraine Jacques, William J. Scotton, Cyril Chacko, Randeep Mullhi, Ruoling Chen, Vikram Patil, Suresh Renukappa, Tonny Veenith   +12 more
wiley   +1 more source

Cuproptosis-driven astrocyte reactivity exacerbates experimental cerebral malaria pathogenesis. [PDF]

Parasit Vectors
Hou X, Mo X, Zhang X, Wang Q, Chen X, Lai C, Gao J, Wu L, Liu W, He J, Zeng X, Yin H, Deng Z, Liu T, Ye M, Liu Z, Jin X, Song J, Wang J, Huang B.   +19 more
europepmc   +1 more source

Author response for "Parallel astrocyte calcium signaling modulates olfactory bulb responses"

, 2020
Kevin Ung, Burak Tepe, Brandon Pekarek, Benjamin R. Arenkiel, Benjamin Deneen   +4 more
openalex   +1 more source