Results 291 to 300 of about 283,599 (345)

From glia limitans to glial scars: in vitro co-culture studies of the astrocyte and meningeal interaction. [PDF]

Fluids Barriers CNS
Reardon EC, Greaney AJ, Mulvihill JJE.
europepmc   +1 more source

Ultrafine Molybdenum Wire Braided Neurointerventional Implants: Bridging Biodegradability and Neurovascular Safety for Stroke Treatment

Advanced Science, EarlyView.
Molybdenum (Mo), with its unique strength, uniform corrosion, and radiopacity, enables innovative biodegradable implants for transformative stroke therapy. Abstract Neurovascular implants for stroke intervention face a critical dilemma: permanent devices (e.g., nitinol stents, platinum coils) often trigger chronic inflammation and recurrence, whereas ...
Yunong Shen, Yiming Huang, Yang Zhang, Chunhao Yu, Hanqi Liu, Dong Bian, Di Wu, Wu Wang, Xunming Ji, Yufeng Zheng, Miaowen Jiang, Ming Li   +11 more
wiley   +1 more source

Mitochondrial fission controls astrocyte morphogenesis and organization in the cortex. [PDF]

J Cell Biol
Rodriguez Salazar MP, Kolanukuduru S, Ramirez V, Lyu B, Manigault G, Sejourne G, Sesaki H, Yu G, Eroglu C.   +8 more
europepmc   +1 more source

Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model

Advanced Science, EarlyView.
Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo, Megi Maci, April M. Stafford, Morgan R. Miller, Stephen J. Perle, Shuzo Inagaki, Shusaku Takahashi, Heather Brown‐Harding, Linda Liang, Alex Lovely, Moustafa Algamal, Rebecca L. Gillani, Theodore J. Zwang, Douglas Richardson, Janice R. Naegele, Daniel Vogt, Ksenia V. Kastanenka   +16 more
wiley   +1 more source

DYRK1A in the physiology and pathology of the neuron-astrocyte axis. [PDF]

Front Neurosci
Cisternas P, Kim J, Ashfeld B, Zartman J.   +3 more
europepmc   +1 more source

CSIG-32. RECURRENT ACROCENTRIC TRANSLOCATIONS AND ANAPHASE BRIDGES ARE AN EARLY PHENOTYPE OF PRE-CANCEROUS ASTROCYTES WITH DYSFUNCTIONAL TELOMERES [PDF]

Ogechukwu Mbegbu, Yue Hao, Noelle Fukushima, Ava Bryan, Tianpeng Zhang, Pippa Cosper, Floris Barthel   +6 more
openalex   +1 more source

Shannon Entropy of Gray Matter Eigenmodes: A Novel Biomarker for Alzheimer's Disease and Heterogeneous MCI Trajectories

Advanced Science, EarlyView.
Entropy derived from gray matter eigenmodes captures cortical disorganization in Alzheimer's disease. Using multimodal MRI and amyloid‐PET data, this novel structure–function coupling biomarker enables accurate classification of clinical stages, predicts Aβ burden, and stratifies mild cognitive impairment subtypes.
Yumeng Li, Gaoping Long, Xinyue Zhang, Kewei Chen, Xin Li, Zhanjun Zhang   +5 more
wiley   +1 more source

The Active Astrocyte: Calcium Dynamics, Circuit Modulation, and Targets for Intervention. [PDF]

Neurochem Res
Rusakov DA, Jensen TP, Tyurikova O.
europepmc   +1 more source

Selective disruption of mTORC1 and mTORC2 in VTA astrocytes induces depression and anxiety-like behaviors in mice

Ziteng Zheng, Han Zhou, Lu Yang, Lanlan Zhang, Ming Guo   +4 more
openalex   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source