Results 161 to 170 of about 2,490,222 (262)

Advanced Experiment Design Strategies for Drug Development

Advanced Intelligent Discovery, Volume 2, Issue 4, August 2026.
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang, Anthony Harker, Mohan Edirisinghe, Maryam Parhizkar   +3 more
wiley   +1 more source

Hijri Month Determination in Southeast Asia: An Illustration Between Religion, Science, and Cultural Background. [PDF]

Heliyon
Mohd Nawawi MSA, Faid MS, Saadon MHM, Wahab RA, Ahmad N.   +4 more
europepmc   +1 more source

Presurgical miR‐675‐5p Associates With the Inflammatory Response Following Surgery and Increases Inflammatory Gene Expression In Vitro

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background A loss of muscle mass and strength is a marker of poor outcomes following surgery. Changes in muscle gene expression following surgery are likely to contribute to postsurgical muscle loss, but the mechanisms controlling these changes are not known. We have previously shown that miRNAs associate with muscle loss in disease, including
Narmin Akhundova, Richard Paul, Benjamin Fletcher, Martin Connolly, Mark J. Griffiths, Paul R. Kemp   +5 more
wiley   +1 more source

Low-temperature gas-phase formation of cyclopentadiene and its role in the formation of aromatics in the interstellar medium. [PDF]

Proc Natl Acad Sci U S A
Yang Z, Medvedkov IA, Goettl SJ, Nikolayev AA, Mebel AM, Li X, Kaiser RI.   +6 more
europepmc   +1 more source

Increasing artificial light at night enhances salmonid predator foraging efficiency in an urbanized lake

Limnology and Oceanography, Volume 71, Issue 8, August 2026.
Abstract Artificial light at night (ALAN) poses a threat to ecosystems globally. It includes both direct and indirect light, or skyglow, which occurs when ALAN scatters in the atmosphere, extending beyond its original source. We analyzed ALAN trends in Lake Washington, WA, from 2014 to 2023 using Visible Infrared Imaging Radiometer Suite (VIIRS ...
Jennifer A. Schulien, Tessa Code
wiley   +1 more source

Atom Addition Formation of Thionylimide (HNSO) on Interstellar Dust Grains: Chemical Routes Requiring Oxygen and Nitrogen Atom Surface Diffusion. [PDF]

ACS Earth Space Chem
Del Valle JC, Sanz-Novo M, Kästner J, Furuya K, Rivilla VM, Martín-Doménech R, Molpeceres G.   +6 more
europepmc   +1 more source

A multidisciplinary experimental and methodological investigation of electron and proton minibeams in the framework of the INFN MIRO project

Medical Physics, Volume 53, Issue 8, August 2026.
Abstract Background The clinical translation of Minibeam RT (MBRT) has recently started thanks to the first human treatments recently performed. However, despite experimental evidence, the impact of the dose distribution parameters involved on the magnitude of the effect itself and the underlying radiobiological mechanisms are still only partially ...
Francesco Romano, Francesca Cella Zanacchi, Esther Ciarrocchi, Gaia Franciosini, Giuliana Milluzzo, Emanuele Scifoni, Anna Vignati, Said Ahmad, Silvia Arezzini, Andrea Attili, Marco Battestini, Jacopo Bernardini, Matteo Bettanin, Alessandra Bisio, Maria Giuseppina Bisogni, Igor Bodrenko, Giulio Bordieri, Valentina Bravatà, Alberto Burattini, Massimo Camarda, Francesco Paolo Cammarata, Simone Capaccioli, Lorenzo Castelli, Andrea Cavalieri, Mariagrazia Celentano, Enrica Chiadroni, Francesco Giuseppe Cordoni, Elena Corvaia, Mario Costa, Alessandro Curcio, Eleonora Da Pozzo, Martina De Felice, Francesca Del Debbio, Francesco D'Errico, Maria Cristina D'Oca, Beatrice D'Orsi, Umberto Deut, Elisabetta Durisi, Maria Evelina Fantacci, Stefano Farina, Giuseppe Felici, Arianna Ferro, Luca Ficcadenti, Antonino Formuso, Giusi Irma Forte, Simona Giordanengo, Alessia Giuliano, Lucia Giuliano, Luca Lanzanò, Stefania Linsalata, Simone Lossano, Margherita Maffei, Michela Marafini, Maurizio Marrale, Maurizio Massa, Luigi Masturzo, Enrico Mazzoni, Mauro Migliorati, Felix Mas Milian, Luigi Minafra, Andrea Moggi, Diango Montalvan Olivares, Marco Montefiori, Matteo Morrocchi, Andrea Mostacci, Franco Mostardi, Chinonso Okpuwe, Fabiola Paiar, Luigi Palumbo, Vincenzo Patera, Jake Harold Pensavalle, Gaia Pucci, Flaminia Quattrini, Alessandra Retico, Valeria Rosso, Giorgio Russo, Roberto Sacchi, Alessio Sarti, Silvia Scalisi, Camilla Scapicchio, Angelo Schiavi, Paolo Stochino, Enrica Strettoi, Francesco Tommasino, Valentina Tozzini, Giacomo Traini, Gabriele Trovato, Alice Usai, Francesco Urso, Fabio Di Martino   +89 more
wiley   +1 more source

Advancing the Frontiers of Alloys and Composites Through Microstructural Design and Property Tailoring. [PDF]

Materials (Basel)
Guo W.
europepmc   +1 more source

An ion treatment planning framework for inclusion of nanodosimetric ionization detail through cluster dose

Medical Physics, Volume 53, Issue 8, August 2026.
Abstract Background Nanodosimetry relates the cumulative or statistical moments of Ionization Detail (ID) with biological endpoints of relevance to cancer radiotherapy using charged particles. This association suggests to develop an additional physics‐detailed layer of modeling that may complement biological modeling and treatment planning.
Simona Facchiano, Ramon Ortiz, Remo Cristoforetti, Naoki D‐Kondo, Oliver Jäkel, Bruce Faddegon, Niklas Wahl   +6 more
wiley   +1 more source

The Density Profile of a Neutron Star. [PDF]

Entropy (Basel)
Woodbury AD.
europepmc   +1 more source