Results 51 to 60 of about 856,713 (267)

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Subclinical rheumatic heart disease: A single center experience

İstanbul Kuzey Klinikleri, 2018
INTRODUCTION[|]Rheumatic heart disease (RHD) is still a major cause of morbidity and mortality in developing countries. The aim of the present study was to investigate asymptomatic RHD cases diagnosed by echocardiography without any acute rheumatic fever
Seyma Kayali, Nuran Belder
doaj   +1 more source

An asymptomatic young lady with multiple inflammatory myofibrolastic tumours

, 2012
Introduction: We report a case of inflammatory myofibroblastic tumour with positive PET-CT involving the lung, hilar lymph node, liver and spleen in an asymptomatic young girl. Diagnosis was made four years after the initial presentation.
Ralib, Razali, Abdul Rani, Mohammed Fauzi, Kuan, Yeh Chunn, How, Soon Hin, Ng, Teck Han, AR, Azlina   +5 more
core   +1 more source

Loop-mediated isothermal amplification (LAMP) for point-of-care detection of asymptomatic low-density malaria parasite carriers in Zanzibar. [PDF]

, 2015
BACKGROUND: Asymptomatic, low parasite density malaria infections are difficult to detect with currently available point-of-care diagnostics. This study piloted a loop-mediated isothermal amplification (LAMP) kit for field-friendly, high-throughput ...
Msellem, Mwinyi, Abass, Ali K, Mårtensson, Andreas, Schmidt, Berit, Abass, Ali K., Berit Aydin-Schmidt, Mwinyi Msellem, Nassor, Majda H, Cook, Jackie, Aydin-Schmidt, Berit, Nassor, Majda H., Björkman, Anders, Abdullah Ali, Elin Edlund, David Bell, Majda H Nassor, Andreas Mårtensson, Jackie Cook, Ali, Abdullah, Mårtensson, Andreas,, Anders Björkman, Gonzalez, Iveth J., González, Iveth J, Bell, David, Edlund, Elin, Ali K Abass, Iveth J González   +26 more
core   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Chronic myeloid leukemia in an asymptomatic young patient: a rare case report [PDF]

Journal of Research in Applied and Basic Medical Sciences
Chronic myeloid leukemia (CML) is a clonal myeloproliferative neoplasm arising from the neoplastic transformation of pluripotent stem cells and is consistently associated with the BCR-ABL fusion gene located on the Philadelphia chromosome.
Urja Bhatt, Hiral Shah
doaj  

SARS-CoV-2 infections among asymptomatic individuals contributed to COVID-19 cases: A cross-sectional study among prospective air travelers from Ghana

Frontiers in Public Health, 2022
BackgroundThe spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by asymptomatic individuals has been reported since the early stages of the coronavirus disease 2019 (COVID-19) outbreak in various parts of the world.
Kwasi A. Akowuah, Richard A. Akuffo, Richard A. Akuffo, Anthony T. Boateng, Theodore W. Asigbee, Joseph H. K. Bonney, Helena Lamptey, Mildred A. Adusei-Poku, Evangeline Obodai, Ivy A. Asante, Samuel Adjei, James O. Aboagye, James O. Aboagye, Susan Adu-Amankwah, Frederica D. Partey, George B. Kyei, George B. Kyei, William K. Ampofo, John K. Odoom, Evelyn Y. Bonney   +19 more
doaj   +1 more source

Effect of physical exercise on pain thresholds and plasma beta-endorphins in patients with silent and symptomatic myocardial ischaemia

, 1988
In a double-blind study, eight patients with symptomatic myocardial ischaemia and nine with asymptomatic myocardial ischaemia were compared during physical exercise under naloxone (6 mg i.v.) or placebo. Plasma beta-endorphin, cortisol and catecholamines
Roskamm, H., Droste, C., Meyer-Blankenburg, H., Greenlee, Mark W.   +3 more
core   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

A community-based study on the prevalence of reproductive tract infections/sexually transmitted infections and their associated factors among married women of reproductive age in Delhi

CHRISMED Journal of Health and Research, 2023
Introduction: Reproductive tract infections/sexually transmitted infections (RTIs/STIs) and their sequelae are an important public health problem, particularly among women.
Preety Doley, Geeta Yadav, Sumathi Muralidhar, Monika Gupta   +3 more
doaj   +1 more source