Results 81 to 90 of about 84,882 (267)

Agent‐Based Simulations of Lung Tumor Evolution Suggest That Ongoing Cell Competition Drives Realistic Clonal Expansions

Advanced Science, EarlyView.
Computational simulations of tumor evolution are increasingly used to infer the rules underlying cancer growth, with the goal of one day recommending tailored treatments. Here we show that the properties of lung cancer sequencing data are best replicated by a model which assumes that cells compete both to proliferate and survive. ABSTRACT Computational
Helena Coggan, James R. M. Black, Carlos Martínez‐Ruiz, Kristiana Grigoriadis, Jasmin Fisher, Nicholas McGranahan   +5 more
wiley   +1 more source

Semi-Analytical Pricing of Barrier Options in a Hybrid Model of Stochastic and Local Volatility

Mathematics
In this paper, the valuation of barrier options is studied when the underlying asset is driven by a hybrid model of stochastic volatility and constant elasticity of variance. Using an asymptotic expansion approach and the Fourier transform method, a semi-
Jiling Cao, Sheng Gong, Xi Li, Wenjun Zhang   +3 more
doaj   +1 more source

Asymptotic Formula for the Moments of Lebesgue’s Singular Function

Моделирование и анализ информационных систем, 2015
Recall Lebesgue’s singular function. Imagine flipping a biased coin with probability p of heads and probability q = 1 − p of tails. Let the binary expansion of ξ ∈ [0, 1]: ξ = ∑∞ k=1 ck2−k be determined by flipping the coin infinitely many times, that is ...
E. A. Timofeev
doaj   +1 more source

Learning Work Function via Implicit Reasoning on Electrostatic Potential Landscapes

Advanced Science, EarlyView.
StructPot‐CLR establishes a cross‐modal contrastive learning framework that aligns the crystal structures of 2D materials with plane‐averaged electrostatic potential landscapes for physically informed work‐function prediction. The model achieves an MAE of 0.265 eV and an R2 of 0.902 on the held‐out test set while accurately preserving key morphological
Haoyu Wan, Yue Wu, Tianhao Su, Deng Pan
wiley   +1 more source

Asymptotic formula for the moments of Bernoulli convolutions

Моделирование и анализ информационных систем, 2016
. Asymptotic Formula for the Moments of Bernoulli Convolutions Timofeev E. A. Received February 8, 2016 For each λ, 0 < λ < 1, we define a random variable ∞ Yλ =(1−λ)ξnλn, n=0 where ξn are independent random variables with P{ξn =0}=P{ξn =1}= 1.
E. A. Timofeev
doaj   +1 more source

Dynamically Tunable Exciton‐Photon Coupling via Multi‐Physics Field in Transition Metal Dichalcogenide Microcavities

Advanced Science, EarlyView.
Dynamic microcavities provide reversible control over exciton‐photon coupling in two‐dimensional TMDs through piezoelectric, electrical, thermal, and all‐optical tuning. By reshaping detuning, Rabi splitting, and polariton composition, these strategies enable adaptable polaritonic functions, including optical switching, polariton lasing, and ...
Jingwen Zhang, Wenqi Qian, Haiyi Liu, Guangyi Tao, Hai Liu, Yifan Zhang, Pengfei Qi, Zheyu Fang   +7 more
wiley   +1 more source

Topology‐Enabled Finite‐Band Absorption Framework Based on a Bioinspired Nested Dual‐Loop Architecture

Advanced Science, EarlyView.
A nuclear‐pore‐inspired nested dual‐loop architecture redistributes electromagnetic energy through coupled transport, confinement, and dissipation pathways. Integrated with Co/Fe3O4 dual‐magnetic composites and topology optimization, the 11‐mm‐thick absorber delivers continuous 2–40 GHz attenuation, raises finite‐band structural utilization to 82%, and
Shaokang Liu, Weicheng Liao, Pinchen Luo, Mengchen Jin, Tangming Yan, Xing Zhao, Qingshan Wang   +6 more
wiley   +1 more source

ACSL4‐Dependent Lysosomal Lipid Peroxidation Links WTAP‐Mediated m6A Modification to Intervertebral Disc Degeneration

Advanced Science, EarlyView.
IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD).
Shu Jia, Xu Gao, Laimin Zhu, Haixia Song, Jing Wu, Shang Chen, Sheng Gao, Lu Zhang, Chunyang Meng   +8 more
wiley   +1 more source

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

Advanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English, Dorothea Böken, Matthew W. Cotton, Matthew R. Cheetham, Johanna S. Jackson, Georg Meisl, John S. H. Danial, Paul M. Matthews, Nurun N. Fancy, David Klenerman   +9 more
wiley   +1 more source

Quicksort asymptotics

Journal of Algorithms, 2002
The number of comparisons X_n used by Quicksort to sort an array of n distinct numbers has mean mu_n of order n log n and standard deviation of order n. Using different methods, Regnier and Roesler each showed that the normalized variate Y_n := (X_n - mu_n) / n converges in distribution, say to Y; the distribution of Y can be characterized as the ...
James Allen Fill, Svante Janson
openaire   +2 more sources