Results 51 to 60 of about 9,889 (218)
Advanced Science, EarlyView.IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD).
Shu Jia +8 more
wiley +1 more source
Advanced Science, EarlyView.The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English +9 more
wiley +1 more source
Seeing the Chemistry of Biomolecular Condensates: In Situ Mapping of Composition and Water Content
Advanced Science, EarlyView.Raman hyperspectral imaging combined with spectral phasor analysis enables a label‐free quantification of proteins, polymers and water density within individual biomolecular condensates. By transforming complex vibrational fingerprints into intuitive compositional maps, the approach reveals the high water content and structural heterogeneity of ...
E. Sabri +3 more
wiley +1 more source
The large-sample asymptotic behaviour of quartet-based summary methods for species tree inference. [PDF]
J Math Biol, 2022 Chan YB, Li Q, Scornavacca C.
europepmc +1 more source
Brain Network Dynamics of Local and Global Predictive Processing in Aging
Advanced Science, EarlyView.Separation of concurrent whole‐brain networks in source‐reconstructed magnetoencephalography (MEG) data suggests that healthy aging reorganizes, rather than uniformly attenuates, neural responses elicited from hierarchical auditory violations. Enhanced early sensory deviance processing alongside reduced higher‐order cognitive responses suggests a large‐
Mathias Houe Andersen +9 more
wiley +1 more source
Asymptotic properties of the von Foerster-Lasota equation and indices of Orlicz spaces
Electronic Journal of Differential Equations, 2016 This article concerns the asymptotic behaviour of the dynamical systems induced by the von Foerster-Lasota equation. We study chaoticity of the system in the sense of Devaney and its strong stability in Orlicz spaces generated by any phi-function.
Antoni Leon Dawidowicz, Anna Poskrobko
doaj
Experiments on Nonlocal Fluid‐Flow Metamaterials
Advanced Science, EarlyView.A nonlocal fluid‐flow metamaterial composed of standard microfluidic tubes and connectors is designed. Hence, the current of the system at one position depends on the gradient of fluid flow at many other positions, leading to unusual alternating backward and forward laminar flows of water.
Ke Wang, Yi Chen, Martin Wegener
wiley +1 more source
Asymptotic Behaviour of Time Stepping Methods for Phase Field Models. [PDF]
J Sci Comput, 2021 Cheng X, Li D, Promislow K, Wetton B.
europepmc +1 more source
Advanced Science, EarlyView.Planar ferroelectric lattices with rationally‐tailored topology and polarization achieve programmable piezoelectric and pyroelectric properties. Analytical modeling, homogenization, and experiments collectively demonstrate enhanced and tunable longitudinal, transverse, and shear piezoelectric responses, together with substantially improved ...
Jiahao Shi +6 more
wiley +1 more source
On asymptotic behaviour in truncated conformal space approach
Journal of High Energy Physics, 2019 The Truncated conformal space approach (TCSA) is a numerical technique for finding finite size spectrum of Hamiltonians in quantum field theory described as perturbations of conformal field theories.
Anatoly Konechny, Dermot McAteer
doaj +1 more source