Results 111 to 120 of about 32,216 (303)

ACSL4‐Dependent Lysosomal Lipid Peroxidation Links WTAP‐Mediated m6A Modification to Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD).
Shu Jia   +8 more
wiley   +1 more source

Joint ruin probability and risk contagion measure in a quota-share reinsurance risk model

open access: yesNonlinear Analysis
Consider a quota-share reinsurance risk model with constant premiums and stochastic returns in which an insurer purchases fixed-proportion quota-share reinsurance for its business line. Both the insurer and reinsurer may engage in risk-free investments,
Yang Yang, Rongshan Huang, Hui Meng
doaj   +1 more source

Asymptotics of the Solution of the Bisingular Problem for a System of Linear Parabolic Equations. II

open access: yesМоделирование и анализ информационных систем, 2013
Suppose we are given a bisingular initial boundary-value problem for a system of parabolic equations that contains a small parameter ε² at the second derivative and √ ε at the first derivative with respect to the spatial variable. We prove an asymptotics
M. V. Butuzova
doaj   +1 more source

Asymptotics of Asynchronicity [PDF]

open access: yes
In this article we focus on estimating the quadratic covariation of continuous semimartingales from discrete observations that take place at asynchronous observation times.
Markus Bibinger
core  

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

open access: yesAdvanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English   +9 more
wiley   +1 more source

Strong Approximations for Nonlinear Transformations of Integrated Time Series [PDF]

open access: yes
In this paper we establish the strong approximations for the nonlinear transformations of integrated time series. Both the asymptotically homogeneous and integrable transformations are considered, and the explicit rates for the convergence to their limit
Park, Joon
core  

Low‐Power Control Of Resistance Switching Transitions in First‐Order Memristors

open access: yesAdvanced Electronic Materials, EarlyView.
Joule losses are a serious concern in modern integrated circuit design. In this regard, minimizing the energy necessary for programming memristors should be handled with care. This manuscript presents an optimal control framework, allowing to derive energy‐efficient programming voltage protocols for resistance switching devices. Following this approach,
Valeriy A. Slipko   +3 more
wiley   +1 more source

Quicksort asymptotics

open access: yesJournal of Algorithms, 2002
The number of comparisons X_n used by Quicksort to sort an array of n distinct numbers has mean mu_n of order n log n and standard deviation of order n. Using different methods, Regnier and Roesler each showed that the normalized variate Y_n := (X_n - mu_n) / n converges in distribution, say to Y; the distribution of Y can be characterized as the ...
James Allen Fill, Svante Janson
openaire   +2 more sources

Electrodeposited Piezoelectric Chitosan Films: A New Approach Toward a Scalable and Standardized Fabrication of Sensors

open access: yesAdvanced Electronic Materials, EarlyView.
Electrodeposition is explored as an innovative and scalable approach to fabricate standardized and highly piezoelectric chitosan films. Chitosan deposition is driven onto gold‐coated silicon plates by an applied voltage. Films’ piezoelectricity is clearly proved and correlated to the material structural order.
Valeria D'Errico   +3 more
wiley   +1 more source

Nonlinear Dynamics and Invariants of Motion in ReRAM Cells

open access: yesAdvanced Electronic Materials, EarlyView.
A second‐order cell, hosting one capacitor and two back‐to‐back ReRAMs, admits Invariants of Motion: its states lie on one‐dimensional manifolds at all times. The cell shows quiescent monostability or bistability, depending on the manifold index. At equilibrium, the capacitor voltage vanishes.
Mauro Di Marco   +5 more
wiley   +1 more source

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