Results 11 to 20 of about 788 (168)

Use of a Cytobrush for Sampling the Ear Canal of Dogs With Otitis Externa. [PDF]

Vet Dermatol
Cytological examination of the ear canal is essential for evaluating dogs with otitis externa (OE). The conventional sampling method uses a swab. However, the cytobrush (gynaecological cervical brush), already used for cytological collection from other anatomical sites, has not been adequately investigated for this purpose in dogs with OE.
Atanasio NR, Ledur GR, Filho DM, Gerardi DG.   +3 more
europepmc   +2 more sources

Development of a Genetically Encoded and Potent PDE6D Inhibitor. [PDF]

Chembiochem
PDE6D is a trafficking chaperone of prenylated proteins. Current small molecule PDE6D inhibitors target its hydrophobic pocket, rendering them typically poorly water soluble. Herein, PDE6D binders are generated by combining parts of the K‐Ras4B and INPP5E C‐termini. The genetically encoded high‐affinity PDE6D inhibitor SNAP‐STI is thus generated.
Gómez-Mulas A, Schaffner-Reckinger E, Peeters H, Chippalkatti R, Dautbasic A, Smith MJ, Ismail S, Abankwa DK.   +7 more
europepmc   +2 more sources

Efficacy of Interventions to Promote Exercise Adherence in People With Overweight or Obesity: A Systematic Review. [PDF]

J Obes
Background The World Health Organization estimates that more than 500 million people will be affected by diseases related to physical inactivity in the next decade. Individuals with overweight or obesity are particularly vulnerable, making exercise adherence a critical public health concern.
Rodrigues MSA, Atanasio LM, Dos Santos IK, da Silva JCG, Cabral BGAT, Dantas PMS.   +5 more
europepmc   +2 more sources

A case of frontal lobe seizures with 'dancing-like' semiology. [PDF]

Eur J Neurol
Abstract Background and purpose ‘Dancing‐like’ semiology is extremely rare and described in few case reports. It is characterized by rhythmic, oscillatory movements of the pelvis and/or limbs during which the subject appears to be dancing. It has been associated with both the frontal and temporal epileptic zone; however, the possible network involved ...
Atanasio G, Germanò A, Granata F, Tomaiuolo F, Labate A.   +4 more
europepmc   +2 more sources

Thermodynamic versus kinetic basis for the high conformational stability of nanobodies for therapeutic applications. [PDF]

FEBS Lett
Nanobodies (NB) are attractive tools for biotechnological and therapeutic applications. NB have high stability, but their denaturation mechanism is unclear. We show that three NB with therapeutic potential and structural similarity largely differ in their thermodynamic stability in a wide range of temperatures.
Gómez-Mulas A, Cano-Muñoz M, Salido Ruiz E, Pey AL.   +3 more
europepmc   +2 more sources

Dupilumab as an Adjunct to Oral Immunotherapy in Pediatric Patients With Peanut Allergy. [PDF]

Allergy
Dupilumab in combination with OIT was well tolerated in children and adolescent patients with peanut allergy, and safety was consistent with the known dupilumab safety profile. A greater number of patients passed a DBPCFC during the OIT up‐dosing period with continuous dupilumab + OIT treatment versus continuous OIT.
Chinthrajah RS, Sindher SB, Nadeau KC, Leflein JG, Spergel JM, Petroni DH, Jones SM, Casale TB, Wang J, Carr WW, Shreffler WG, Wood RA, Wambre E, Liu J, Akinlade B, Atanasio A, Orengo JM, Hamilton JD, Kamal MA, Hooper AT, Patel K, Laws E, Mannent LP, Adelman DC, Ratnayake A, Radin AR.   +25 more
europepmc   +2 more sources

Noninvasive Methods Unveil the Trophic Transmission of the Tapeworm Ligula intestinalis in Gull-Billed Terns. [PDF]

Ecol Evol
Using both copromicroscopic (Mini‐FLOTAC) and molecular (qPCR) techniques, we detected and quantified the macroparasite Ligula intestinalis in Gull‐billed Terns for the first time. Phylogenetic analyses revealed genetic similarities among parasite isolates from birds (definitive hosts) and fish prey (intermediate hosts), suggesting local infection from
Capasso S, Parejo M, Reyes-González JM, Navedo JG, Morán-López R, Masero JA, Gutiérrez JS.   +6 more
europepmc   +2 more sources

La violencia religiosa cristiana en la Historia Eclesiástica de Sócrates durante el gobierno de Teodosio II y en la Historia Eclesiástica de Teodoreto de Cirro

Gerión, 2009
. La violencia cristiana en la Historia Eclesiástica de Sócrates durante el gobierno de Teodosio II, y en la Historia Eclesiástica de Teodoreto de Cirro. Cirilo en Alejandría. Concilio de Éfeso. Siervos. Los novacianos. Los judíos. Monjes.
José María Blázquez Martínez
doaj   +2 more sources

El estallido de la controversia arriana

Espacio, Tiempo y Forma. Serie II, Historia Antigua, 1996
Este artículo estudia el inicio de la disputa arriana. Fuentes: Epifanio de Salamina, Eusebio de Cesárea, Basilio de Cesárea, Filoslorgio, Rufino de Aquileya, Sócrates, Procopio de Cesárea, Sozomeno, Atanasio de Alejandría y Teodoreto de Ciro.
Gonzalo Fernández
doaj   +1 more source

C9orf72 Repeat Expansion Induces Metabolic Dysfunction in Human iPSC‐Derived Microglia and Modulates Glial‐Neuronal Crosstalk

Glia, Volume 74, Issue 1, January 2026.
C9orf72 microglia display heightened glycolysis and oxidative stress, driving astrocytic reprogramming that impacts motor neurons. iPSC tricultures uncover key glial–neuronal interactions in C9orf72 pathology. ABSTRACT The C9orf72 hexanucleotide repeat expansion mutation is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and ...
Marika Mearelli, Insa Hirschberg, Christin Weissleder, Carmela Giachino, María José Pérez, Malvina Dubroux, Francesca Provenzano, Mafalda Rizzuti, Linda Ottoboni, Udit Sheth, Tania F. Gendron, Stefania Corti, Michela Deleidi   +12 more
wiley   +1 more source