Results 171 to 180 of about 99,306 (231)

High‐Purity Functional Corneal Endothelial Cells From Human Induced Pluripotent Stem Cells via a Novel Wash‐Out Method

MedComm, Volume 7, Issue 4, April 2026.
iPSC‐derived corneal endothelial cells purified via a novel wash‐out method show high functional fidelity, resemble primary CECs, and restore corneal clarity in vivo, offering a scalable alternative to donor transplantation. ABSTRACT Corneal endothelial failure can cause blindness, with transplantation as the only treatment.
Eun‐Ah Ye, Changmin Kim, Minah Jeon, Yeji Yoon, Jiyoon Park, Ryun Hee Lee, Carson Yu, Ho Seok Chung, Jae Yong Kim, David Myung, Hun Lee   +10 more
wiley   +1 more source

Modeling and Simulation in Development and Regulatory Approval of Chimeric Antigen Receptor T‐Cell Therapies: An Analysis of European Medicines Agency Centralized Procedures From 2018 to 2024

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 4, April 2026.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapies represent a major advancement in oncology. These therapies have demonstrated therapeutic potential, particularly in hematological malignancies where patients have relapsed or are refractory to prior treatments.
Lisa Hanquet, Jean‐Michel Dogné, Flora T. Musuamba   +2 more
wiley   +1 more source

IUCN Red List Regional Assessment of the Flora of Niue Utilising Indigenous Local Knowledge and Botanical Information

Journal of the Royal Society of New Zealand, Volume 56, Issue 2, April 2026.
A regional assessment of the indigenous vascular plants of Niue is presented using the IUCN Red List criteria. The assessment was undertaken during a community workshop that drew on the indigenous local knowledge and scientific information. The assessment comprised 197 named taxa and 8 indeterminate entities, with 4 (2.0%) taxa assessed as Extinct and ...
Peter B. Heenan, Huggard E. Tongatule, Workshop Panel   +2 more
wiley   +1 more source

Comparative Analysis of Lavandula Dentata Rhizosphere Microbiota Across Different Developmental Stages in a Semi‐Arid Area

Environmental Microbiology Reports, Volume 18, Issue 2, April 2026.
This study aims to give deeper insight into the relationship between the dynamics of the rhizospheric microbiota and the developmental stages of L. dentata growing spontaneously in a semi‐arid environment. To achieve this objective, we examined and monitored the biomass (using phospholipid fatty acid, PLFA analysis), diversity and network complexity of
Oumaima Akachoud, Julien Langrand, Hafida Bouamama, Natacha Facon, Frédéric Laruelle, Ahmed Qaddoury, Anissa Lounès ‐Hadj Sahraoui   +6 more
wiley   +1 more source

Evaluating bridge‐building strategies: How direct and indirect contact with refugees in Italian welcome projects promotes positive intergroup relations

Analyses of Social Issues and Public Policy, Volume 26, Issue 1, April 2026.
Abstract According to Allport's Contact Hypothesis, contact with individuals from different social groups fosters positive intergroup relations under certain conditions. Building on this theoretical framework, we examined the effects of direct (Study 1) and indirect (extended; Study 2) contact with refugees within (two different types of) Italian ...
Tiziana Mancini, Chiara Imperato, Mattia Messena   +2 more
wiley   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, Volume 101, Issue 2, Page 751-803, April 2026.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Enhanced Wound Healing Through Air‐Break Augmentation of Hyperbaric Oxygen Therapy Combined With Adipose‐Derived Stromal Cell Transplantation in a Murine Model

International Wound Journal, Volume 23, Issue 4, April 2026.
ABSTRACT Hyperbaric oxygen therapy (HBOT) enhances wound healing by promoting angiogenesis and reducing hypoxia. However, the role of air‐breaks—intermittent exposures to ambient air during HBOT—remains unclear. We investigated the effects of air‐breaks on HBOT‐mediated wound healing, particularly in combination with adipose‐derived stromal cells (ASCs)
Eun Hee Ha, Heewoong Yang, Soohyun Kim, Jeong Eun Shin, Ji‐Yeon Bae, Ki Yong Hong, Hak Chang   +6 more
wiley   +1 more source

Dietitians as System Builders: Advancing Equity, Sustainability and Health in Community Nutrition and Primary Care

Journal of Human Nutrition and Dietetics, Volume 39, Issue 2, April 2026.
ABSTRACT Diet‐related challenges in primary care and community settings increasingly reflect the convergence of health, social and environmental pressures. Although dietitians routinely navigate this complexity, their system‐level contributions often remain implicit.
Elena Carrillo‐Alvarez, Yael Puyol‐Martin, Aina Camps, Júlia Muñoz‐Martinez, Míriam Rodriguez‐Monforte, Sofia Berlanga‐Fernandez, Mariona Rigau‐Sabadell   +6 more
wiley   +1 more source

Biocatalysis Under Reduced Pressure; Two‐Step, One‐Pot Amide Synthesis Using an Immobilised Transaminase/Lipase Cascade in Combination With By‐Product Removal

ChemBioChem, Volume 27, Issue 6, 27 March 2026.
The application of biocatalytic cascades for organic synthesis can be encouraged through the use of easy‐to‐handle, immobilised enzymes and common laboratory equipment. We present a sequential biocatalytic cascade reaction that couples a transaminase (ATA) with a lipase, and achieves high conversion and enantioselectivity through by‐product removal ...
Lisa Kennedy, Nicholas Mulholland, Andrew Gomm, Dominic J. Campopiano   +3 more
wiley   +1 more source

Synthesis of Niraparib via Chemoenzymatic Dearomatization of Substituted Pyridines

Advanced Synthesis &Catalysis, Volume 368, Issue 6, 17 March 2026.
The synthesis of the PARP inhibitor Niraparib has been achieved via a chemoenzymatic dearomatization strategy. Chemical reduction combined with a one‐pot enzymatic cascade comprising an amine oxidase (AmOx) and an ene imine reductase (EneIRED) allowed for asymmetric reduction with high enantioselectivity.
Tabea Gerlach, Lucian Pirvu, Sam Butterworth, Nicholas J. Turner   +3 more
wiley   +1 more source