Results 131 to 140 of about 77,321 (235)
MedComm, Volume 7, Issue 9, September 2026.Microbial signals from gut and tumor‐resident bacteria, fungi, viruses, and bacteriophages reshape immune and metabolic networks within the tumor microenvironment, thereby influencing cancer progression, treatment response. Therapeutic modulations, including dietary interventions, probiotics, antibiotics, fecal microbiota transplantation, engineered ...
Juan Lu +8 more
wiley +1 more source
Cytoskeletal pathology in ataxia-telangiectasia.
, 1988 Neuropathological features of a case of ataxia-telangiectasia are reported. The main findings were the presence of Lewy bodies, cytoplasmic inclusions and axonal spheroids in the brainstem nuclei; pathological changes of spinal cord closely resembled ...
CAVALLARO, Tiziana +4 more
core +1 more source
Case Report: Neuro-Imaging Findings in Ataxia Telangiectasia
Journal of Rehabilitation, 2004 Ataxia Telangiectasia (AT) is an autosomal recessive inherited disorder in which cutaneous and scleral Telangiectasia, cerebellar ataxia and immunodeficiency occur.
Farhad Mahvelati +1 more
doaj
Precision Radiation Oncology, Volume 10, Issue 3, Page 403-416, September 2026.This review summarizes how combining radiotherapy with immune checkpoint inhibitors overcomes the immunosuppressive brain microenvironment in non‐small cell lung cancer (NSCLC) brain metastases. The synergy enhances immune cell infiltration and systemic anti‐tumor activity, improving survival outcomes for patients.
Silai Yu +7 more
wiley +1 more source
ChemistrySelect, Volume 11, Issue 36, 22 September 2026.Burmannic acid (BURA) boosts radiosensitivity in oral cancer: combined with x‐rays, it suppresses tumor growth while sparing normal cells by increasing reactive oxygen species (ROS, MitoSOX), causing G2/M arrest, sub‐G1 accumulation, mitochondrial dysfunction, DNA damage, and apoptosis; these effects are reversed by N‐acetylcysteine. Therefore, BURA is
Kun‐Han Yang +9 more
wiley +1 more source
Current and potential therapeutic strategies for the treatment of ataxia-telangiectasia
, 2007 Ataxia-telangiectasia (A-T) is a rare autosomal recessive genetic disorder characterized by progressive neurodegeneration, a high risk of cancer and immunodeficiency. These patients are also hypersensitive to radiotherapy.
Bottle, S (15815519) +3 more
core
Journal of Medical Imaging and Radiation Oncology, Volume 70, Issue 6, Page 561-572, September 2026.ABSTRACT Neurointerventional procedures can deliver high localised skin doses and may cause radiation‐induced cutaneous tissue reactions, yet the doses at which these occur have not been synthesised specifically for this setting. We systematically reviewed reported cutaneous reactions and associated radiation doses after fluoroscopy‐ or digital ...
Mohamed Khaldoun Badawy +5 more
wiley +1 more source
DHCR24 Alleviates DNA Damage in Senescent Vascular Endothelial Cells via ENKUR/Ca2+ Signaling
Aging Cell, Volume 25, Issue 9, September 2026.In senescent vascular endothelial cells, DHCR24 deficiency triggers ENKUR‐dependent Ca2+ overload, which in turn induces endoplasmic reticulum stress and mitochondrial dysfunction, ultimately exacerbating oxidative stress and DNA damage. ABSTRACT DNA damage is considered one of the major contributors to aging.
Han Li +11 more
wiley +1 more source
British Journal of Haematology, Volume 209, Issue 3, Page 988-997, September 2026.Selinexor targets molecular pathways critical to myelofibrosis (MF) progenitor cell fitness and demonstrates complementary activity with ruxolitinib, supporting its potential as a novel disease‐modifying therapeutic strategy for MF. Summary Myelofibrosis (MF) is a chronic myeloproliferative neoplasm (MPN) characterized by splenomegaly, constitutional ...
Trinayan Kashyap +7 more
wiley +1 more source