Results 221 to 230 of about 186,958 (312)

Characterizing the effects of anti-PD1 immunotherapy on ataxia in a vestibular schwannoma mouse model. [PDF]

J Neurooncol
Lu S, Hernandez-Meadows M, Yin Z, Xiu B, Jones AP, Welling DB, Xu L.   +6 more
europepmc   +1 more source

A first in disease trial of the safety, tolerability, and anti‐seizure effects of ES‐481 in drug‐resistant epilepsy

Epilepsia Open, EarlyView.
Abstract Objectives ES‐481 is a novel potent and selective antagonist of TARP‐y8‐dependent AMPA receptors. We aimed to assess the potential efficacy, safety and tolerability, and pharmacokinetics of different doses of ES‐481 as an add‐on anti‐seizure medication (ASM) in adults with drug‐resistant epilepsy (DRE). Methods This was a Phase 2A double‐blind,
Emma C. Foster, Lyn Millist, Jack Germaine, Stephanie Chamorro, Caitlin Roberts, John‐Paul Nicolo, Sean Hosking, Piero Perucca, Saul Mullen, Heather Robinson, Rebecca Wharrie, Brittany Walsh, David Reutens, Kimberley Irwin, Hao Zeng, Robert Niecestro, Terence J. O'Brien   +16 more
wiley   +1 more source

Paraneoplastic neurologic syndrome in a 65-year-old woman with small cell lung cancer. [PDF]

CMAJ
Hiraoka Y, Hosoi Y, Yasumi K, Ozawa Y.
europepmc   +1 more source

Real‐world effectiveness of cenobamate in drug‐resistant and ultra‐refractory epilepsy: A multicenter study

Epilepsia Open, EarlyView.
Abstract Objective To evaluate the real‐world effectiveness, safety, and treatment retention of cenobamate (CNB) in patients with drug‐resistant epilepsy (DRE), including ultra‐refractory epilepsy (URE), high seizure burden, and extensive prior treatment history.
Ondřej Strýček, Jana Amlerová, Martin Pail, Jitka Kočvarová, Jana Slonková, Martin Šimčík, Kateřina Stanzelová, Monika Šibalová, Petr Marusič, Milan Brázdil   +9 more
wiley   +1 more source

Diagnostic value of genetic testing in chorea: a retrospective monocentric study. [PDF]

J Neurol
Fodor TA, Milenkovic I, Zimprich A, Brücke C.   +3 more
europepmc   +1 more source

Clinical and research applications of synthetic bone substitutes in equine veterinary medicine: A systematic review

Equine Veterinary Journal, EarlyView.
Abstract Background Bone grafting in equine medicine offers a promising contribution to treating orthopaedic developmental diseases and chondral, osteochondral and segmental bone defects. Among grafts, synthetic bone substitutes—alloplastics—show favourable biological properties addressing numerous limitations presented by autografts, xenografts and ...
Katarzyna Skierbiszewska, Bernard Turek, Tomasz Jasiński, Michał Kaczorowski, Natalia Kozłowska, Julia Higuchi, Małgorzata Domino   +6 more
wiley   +1 more source

Contrastive Learning Model for Wearable-Based Ataxia Assessment. [PDF]

IEEE Trans Biomed Eng
Lee J, Oubre B, Daneault JF, Stephen CD, Schmahmann JD, Gupta AS, Lee SI.   +6 more
europepmc   +1 more source

Quality of Spontaneous and Backslopped Fermented Cassava Flour From Different Cassava Landraces and Sensory Acceptability of the Cooked Dough

Food Chemistry International, EarlyView.
The cooked Oko‐iyawo spontaneously fermented cassava flour's sensory acceptability was correlated with its amylose content, pH, pasting temperature, and water absorption capability. Cassava processors may be able to create consistently high‐quality fermented cassava flour for various end users with the use of the information provided in this study ...
Awoyale Wasiu, Yusuf O. Joshua, Irondi A. Emmanuel, Abdulrahman L. Ololade, Allie Georgiana, Olatoye K. Kazeem, Maziya‐Dixon Busie   +6 more
wiley   +1 more source

Early Neuroimmune Modulation in Hereditary Cerebellar Ataxias: Experimental Opportunities in Zebrafish Models. [PDF]

Cells
Naef V, Giacich M, Damiani D, Santorelli FM.   +3 more
europepmc   +1 more source