Results 71 to 80 of about 161,555 (138)

Pruritus is a common feature in sheep infected with the BSE agent. [PDF]

, 2008
BACKGROUND: The variability in the clinical or pathological presentation of transmissible spongiform encephalopathies (TSEs) in sheep, such as scrapie and bovine spongiform encephalopathy (BSE), has been attributed to prion protein genotype, strain ...
Bellworthy, SJ, Berthelin-Baker, C, Bone, G, Chaplin, MJ, Davis, A, Dexter, G, Hill, P, Jeffrey, M, Konold, T, Simmons, MM, Tortosa, R, Vidal-Diez, A   +11 more
core   +3 more sources

More Than Ataxia: Hyperkinetic Movement Disorders in Childhood Autosomal Recessive Ataxia Syndromes

Tremor and Other Hyperkinetic Movements, 2016
Background: The autosomal recessive ataxias are a heterogeneous group of disorders that are characterized by complex neurological features in addition to progressive ataxia.
Toni S. Pearson
doaj   +1 more source

MALT1 proteolytic activity suppresses autoimmunity in a T cell intrinsic manner [PDF]

, 2019
MALT1 is a central signaling component in innate and adaptive immunity by regulating NF-kappa B and other key signaling pathways in different cell types. Activities of MALT1 are mediated by its scaffold and protease functions.
Baens, Mathijs, Beyaert, Rudi, Demeyer, Annelies, Driege, Yasmine, Hochepied, Tino, Kreike, Marja, Skordos, Ioannis, Staal, Jens   +7 more
core   +2 more sources

An ataxia test battery not requiring the use of rails [PDF]

Ataxia on normal humans and those with vestibular defects and ...
Fregly, A. R., Graybiel, A.
core   +1 more source

Üner Tan Syndrome: Review and Emergence of Human Quadrupedalism in Self-Organization,\ud Attractors and Evolutionary Perspectives\ud [PDF]

, 2012
The first man reported in the world literature exhibiting habitual quadrupedal locomotion was discovered by a British traveler and writer on the famous Baghdat road near Havsa/Samsun on the middle Black-Sea coast of Turkey (Childs, 1917).
Karaca, Dr. Sibel, Tamam, Prof. Dr. Yusuf, Tan, Prof. Dr. Meliha, Tan, Prof. Dr. Uner   +3 more
core  

Downbeat nystagmus and progressive ataxia in adults: consider Chiari malformation type 1

Arquivos de Neuro-Psiquiatria, 2023
Breno Kazuo Massuyama, Thiago Cardoso Vale, Flávio Moura Rezende Filho, Orlando Graziani Povoas Barsottini, José Luiz Pedroso   +4 more
doaj   +1 more source

HMGB2-induced calreticulin translocation required for immunogenic cell death and ferroptosis of cancer cells are controlled by the nuclear exporter XPO1

Communications Biology
Cisplatin and oxaliplatin cause the secretion of high mobility group box 1 (HMGB1) protein from cancer cells, which is necessary for initiation of immunogenic cell death (ICD). Calreticulin (CRT) translocation from the endoplasmic reticulum to the plasma
Jingqi Fan, Kevin P. Gillespie, Clementina Mesaros, Ian A. Blair   +3 more
doaj   +1 more source

Emerging antioxidant therapies in Friedreich’s ataxia

Frontiers in Pharmacology
Friedreich’s ataxia (FRDA) is a rare childhood neurologic disorder, affecting 1 in 50,000 Caucasians. The disease is caused by the abnormal expansion of the GAA repeat sequence in intron 1 of the FXN gene, leading to the reduced expression of the ...
Fred Jonathan Edzeamey, Zenouska Ramchunder, Charareh Pourzand, Charareh Pourzand, Sara Anjomani Virmouni   +4 more
doaj   +1 more source

PLS3 Overexpression Delays Ataxia in Chp1 Mutant Mice

Frontiers in Neuroscience, 2019
Many neurodegenerative disorders share common pathogenic pathways such as endocytic defects, Ca2+ misregulation and defects in actin dynamics. Factors acting on these shared pathways are highly interesting as a therapeutic target.
Eva Janzen, Lisa Wolff, Natalia Mendoza-Ferreira, Kristina Hupperich, Andrea Delle Vedove, Seyyedmohsen Hosseinibarkooie, Min Jeong Kye, Brunhilde Wirth, Brunhilde Wirth   +8 more
doaj   +1 more source

The Effect of Nicotine on Spinocerebellar Ataxia [PDF]

, 1955
J. D. Spillane
openalex   +1 more source