Results 161 to 170 of about 78,816 (306)

Amyloid-targeting PET tracer [¹⁸F]Flutemetamol accumulates in atherosclerotic plaques

, 2019
Atherosclerosis is characterized by the accumulation of oxidized lipids in the artery wall, which triggers an inflammatory response. Oxidized low-density lipoprotein (ox-LDL) presents amyloid-like structural properties, and different amyloid species have
Eskola, O. (Olli), Hörkkö, S. (Sohvi), Kiugel, M. (Max), Roivainen, A. (Anne), Ylä-Herttuala, S. (Seppo), Hakovirta, H. (Harri), Liljenbäck, H. (Heidi), Saukko, P. (Pekka), Hirani, E. (Ella), Saraste, A. (Antti), Silvola, J. M. (Johanna M.U.), Knuuti, J. (Juhani), Hellberg, S. (Sanna), Morisson-Iveson, V. (Veronique)   +13 more
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Association Between Triglyceride‐Glucose Index and in‐Hospital Intensive Care Unit Readmission in Ischemic Stroke Patients: A Retrospective Analysis Based on the MIMIC‐IV Database

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This retrospective cohort study utilized the Medical Information Mart for Intensive Care database to investigate the association between the triglyceride–glucose (TyG) index and in‐hospital intensive care unit (ICU) readmission in patients with ischemic stroke (IS). Among 2929 patients, 24.0% experienced ICU readmission.
Di Zhang, Ying‐Lun Chen, Jian Zhang, Xiang‐Jun Hu   +3 more
wiley   +1 more source

Olfactory Dysfunction and Metabolic Syndrome Components: A Systematic Review and Meta‐Analysis

The Laryngoscope, EarlyView.
ABSTRACT Objective To elucidate the association between olfactory dysfunction (OD) and metabolic syndrome components. Data Sources PubMed (National Library of Medicine—National Institutes of Health), Scopus (Elsevier), CINAHL Complete (EBSCOhost), and the Cochrane Library (Wiley) databases were searched from inception through March 23rd, 2026.
Neeti Gandra, Kaitlyn A. Roberts, Shaun A. Nguyen, Pete Peters, Lauren A. Howser, Zachary M. Soler, Rodney J. Schlosser   +6 more
wiley   +1 more source

Unraveling the Shared Genetic Architecture and Molecular Mechanisms Linking Cardiovascular Traits and Glaucoma: A Comprehensive Cross‐Trait Analysis

Medicine Advances, EarlyView.
This study investigates the shared genetic architecture between eight cardiovascular traits and glaucoma using comprehensive cross‐trait analysis. We identified 9948 pleiotropic loci, 71 colocalized signals, and 24 shared genes, with BCAS3, BICC1, FAM213A, ITGB5, NUP160, and TNS1 emerging as robust cross‐trait candidates.
Junfei Huang, Zejun Chen, Mengqing Lin, Bingyu Xu, Qiang Liu, Zhengran Li, Jianping Gao, Guoguo Yi, Min Fu   +8 more
wiley   +1 more source

Intravascular position-sensitive positron-counting catheter for atherosclerotic plaques. [PDF]

EJNMMI Phys
Nakahara T, Fujimoto S, Narula J, Strauss HW, Narula N, Minamino T, Daida H, Jinzaki M.   +7 more
europepmc   +1 more source

Quantitative Susceptibility Mapping of Kidney Stones: An Ex Vivo MRI Phantom Study

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To visualize and characterize the five most common kidney stone types based on their magnetic susceptibilities in MRI using QSM. Methods Three water‐based agar phantoms were constructed, containing a total of 53 ex vivo kidney stones of varying types and sizes.
Lion H. Mücke, Frederik B. Laun, Ruben de Figueiredo Cardoso, Guillaume Flé, Jennifer Lorenz, Alexander Fichte, Michael Uder, Nadine Bayerl, Jannis Hanspach   +8 more
wiley   +1 more source

Citrullination Accompanies the Development of Carotid Atherosclerotic Plaques. [PDF]

Curr Med Chem
Kanonykina A, Velikanova E, Markova V, Bogdanov L, Shishkova D, Shabaev A, Sinitsky M, Sinitskaya A, Poddubnyak A, Lazebnaya A, Stepanov A, Tyurina A, Lobov A, Zainullina B, Yuzhalin A, Kutikhin A.   +15 more
europepmc   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

TWIST1 drives endothelial-to-mesenchymal-transition to stabilize atherosclerotic plaques. [PDF]

Nat Commun
Tardajos Ayllon B, Diagbouga M, Das A, Tian S, Edsfeldt A, Kalucka J, Serbanovic-Canic J, Chambers E, Sun J, Gialeli C, Dunning M, Francis SE, Li X, Mammoto A, Simons M, Jørgensen HF, Goncalves I, Xu S, Evans PC.   +18 more
europepmc   +1 more source

Therapeutic strategies to deplete macrophages in atherosclerotic plaques

, 2012
: Macrophages can be found in all stages of atherosclerosis and are major contributors of atherosclerotic plaque development, progression and destabilization.
Martinet, Wim, De Meyer, Inge, De Meyer, Guido   +2 more
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