Results 341 to 350 of about 503,928 (378)

Rational Design of a Double-Locked Photoacoustic Probe for Precise In Vivo Imaging of Cathepsin B in Atherosclerotic Plaques.

Journal of the American Chemical Society, 2023
Atherosclerotic plaque rupture is a significant cause of acute cardiovascular events such as heart attack and stroke, triggered by the decomposition of fiber caps induced by cysteine cathepsin.
Yuan Ma, Jinhui Shang, Liuhui Liu, Menghuan Li, Xinyu Xu, Hui Cao, Li Xu, Wei Sun, Guosheng Song, Xiao-Bing Zhang   +9 more
semanticscholar   +1 more source

Targeting the Microenvironment of Vulnerable Atherosclerotic Plaques: An Emerging Diagnosis and Therapy Strategy for Atherosclerosis

Advances in Materials, 2022
Atherosclerosis is considered one of the primary causes of cardiovascular diseases (CVDs). Unpredictable rupture of the vulnerable atherosclerotic plaques triggers adverse cardiovascular events such as acute myocardial syndrome and even sudden cardiac ...
Shuai Zhang, Yang Liu, Yue Cao, Songtao Zhang, Jian Sun, Yinghui Wang, Shuyan Song, Hongjie Zhang   +7 more
semanticscholar   +1 more source

Atherosclerotic Plaque Healing

New England Journal of Medicine, 2020
Atherosclerotic Plaque Healing Atherosclerotic plaque rupture and erosion result in acute coronary syndromes. Plaque healing after initial disruption has been less extensively studied.
Vergallo R, Crea F
openaire   +2 more sources

Atherosclerotic plaque development

The International Journal of Biochemistry & Cell Biology, 2009
Atherosclerosis is now recognized as an inflammatory/immunomodulatory reaction to the presence of oxidized low-density lipoproteins within the arterial wall, often times in the setting of such risk factors as family history, hypercholesterolemia, high blood pressure, diabetes mellitus and smoking.
Quang T, Bui, Maxwell, Prempeh, Robert L, Wilensky   +2 more
openaire   +2 more sources

Devouring atherosclerotic plaques

Nature Nanotechnology, 2020
Targeting of local macrophages by functionalized carbon nanotubes enables efferocytosis and clearance of atherosclerotic plaques.
openaire   +2 more sources

Engineering Nanoplatforms for Theranostics of Atherosclerotic Plaques

Advanced Healthcare Materials
Atherosclerotic plaque formation is considered the primary pathological mechanism underlying atherosclerotic cardiovascular diseases, leading to severe cardiovascular events such as stroke, acute coronary syndromes, and even sudden cardiac death.
Yuying Liu, Zeyu Jiang, Xiao Yang, Yin Wang, Bin Yang, Qinrui Fu   +5 more
semanticscholar   +1 more source

Imaging of atherosclerotic plaque

The International Journal of Cardiovascular Imaging, 2004
The behavior and composition of coronary atherosclerotic plaques are ultimately responsible for the threat of acute ischemic events in patients with coronary artery disease. Different imaging modalities have been developed over the last several years in order to better characterize the atherosclerotic plaque and attempt to predict those in peril of ...
Mario A, Pulido, Dominick J, Angiolillo, Marco A, Costa   +2 more
openaire   +2 more sources

Promoting the Delivery of Nanoparticles to Atherosclerotic Plaques by DNA Coating.

ACS Applied Materials and Interfaces, 2018
Many nanoparticle-based carriers to atherosclerotic plaques contain peptides, lipoproteins, and sugars, yet the application of DNA-based nanostructures for targeting plaques remains infrequent.
Lei Zhang, X. Tian, C. K. W. Chan, Qianqian Bai, Chak Kwong Cheng, Francis M Chen, Maggie S. H. Cheung, Bohan Yin, Hongrong Yang, W. Yung, Zhongmiao Chen, Fei Ding, K. Leung, Chuan Zhang, Yu Huang, J. Lau, C. H. J. Choi   +16 more
semanticscholar   +1 more source

Noninvasive Coronary Atherosclerotic Plaque Imaging

JACC: Cardiovascular Imaging, 2023
Coronary artery disease is the leading cause of morbidity and mortality worldwide. Despite remarkable advances in the management of coronary artery disease, the prediction of adverse coronary events remains challenging. Over the preceding decades, considerable effort has been made to improve risk stratification using noninvasive imaging.
Jacek Kwiecinski, Evangelos Tzolos, Michelle C. Williams, Damini Dey, Daniel Berman, Piotr Slomka, David E. Newby, Marc R. Dweck   +7 more
openaire   +2 more sources

Development of atherosclerotic plaques

Acta Medica Scandinavica, 1985
ABSTRACT. Atherosclerosis is a multifactorial disease. A unified model for the lesion development reveals many connections between the response‐to‐injury hypothesis and the lipid hypothesis. Various cellular uptake mechanisms for native and modified lipoproteins are discussed with respect to foam cell formation and lesion development.
openaire   +2 more sources