Results 91 to 100 of about 132,036 (267)
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley +1 more source
Identification of Metabolites of the Dietary Supplement Ingredient 5α‐Hydroxy‐Laxogenin
The biotransformation of the dietary supplement ingredient 5α‐hydroxy‐laxogenin was investigated using human HepG2 cells, the rat and in silico using the online software Next‐gen E‐Resource for Drug Discovery (NERDD). We identified five metabolites generated by the human HepG2 cells of which three and an additional mono‐hydroxylated metabolite were ...
Daniel Derwand +3 more
wiley +1 more source
Smartphone Addiction and Related Factors among Athletes
Smartphone addiction (SA) is increasing worldwide. The aim of this study is to determine the level of SA in athletes affiliated to the Turkish Handball Federation in Izmir and to examine its relationship with factors such as sociodemographic status ...
Sultan Sahin Koybulan +3 more
doaj +1 more source
A two‐stage transcriptomic filter comparing rHuEPO, exercise and altitude responses reduced 153 candidate genes to 50 that were unaffected by physiological stimuli. These retained transcripts offer focused biomarker leads to strengthen antidoping detection of rHuEPO.
Daria Obratov +4 more
wiley +1 more source
Despite accumulating evidence that suggests a unique gut microbiota composition in athletes, a comprehensive understanding of this phenomenon is lacking.
Kazuya Toda +11 more
doaj +1 more source
The paper describes an investigation related to the pentedrone norephedrine metabolite. The athlete's sample was analyzed using ultra‐performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS). According to the literature, this metabolite may originate from pentedrone, α‐pyrrolidinopentiophenone (PVP), or N‐ethylpentedrone (NEP).
D. Kwiatkowska +8 more
wiley +1 more source
A basic EPO IEF profile was identified in patients with familial erythropoiesis linked to mutations in noncoding parts of EPO gene. Comparison of blood and urine EPO profiles from these patients differed from adult wild‐type EPO (WT) and from Eprex‐administered patients. Patients' EPO do not differ from WT EPO after analysis using SDS‐PAGE/SAR‐PAGE. It
Laurent Martin +9 more
wiley +1 more source
The study developed a single Abnormal Steroid Profile Score (ASPS) to improve interpretation of the Athlete Biological Passport steroid module. Using Bayesian modelling and logistic regression, biomarker patterns from laboratory and doping control data successfully discriminated between doped and clean individuals, with improved classification ...
James G. Hopker +3 more
wiley +1 more source
ABSTRACT Objective Social comparison has been widely implicated in the etiology and maintenance of body dissatisfaction and eating disorders. At the same time, however, the magnitude of this relationship remains unclear, with existing studies varying widely in methodology, measurement, and sample characteristics.
Fidan Turk +5 more
wiley +1 more source
Gut‐microbiota‐brain Axis and post‐traumatic epilepsy
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley +1 more source

