Results 51 to 60 of about 639,834 (263)

A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer

Advanced Science, EarlyView.
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang, Xiang Chen, Xiaoxiao Yang, Muskan Gori, Rohit Kumar Varshnaya, Dongning Liu, Cheryl Zhang, Michelle Yi Qin Chen, Zhengming Chen, George Zhang, Erika Patel, Qiyue Mao, Tan A. Ince, Chalet Tan, Binghe Wang, Yi‐Chieh Nancy Du   +15 more
wiley   +1 more source

Fatigue development mechanisms during increased intensity exertion

Central European Journal of Sport Sciences and Medicine, 2013
During motor preparation, the attention is paid more and more frequently to the complex significance of fatigue in the case of the achieved sport outcome. The complexity of this process has not been utterly explained so far.
Sebastian Klich
doaj  

The Development and Validation of a Questionnaire That Assesses Female Athletes’ and Coaches’ Knowledge of the Menstrual Cycle

European Journal of Sport Science
In this study, a menstrual cycle knowledge questionnaire (MCKQ) for female athletes and coaches was developed and validated. Items for an initial questionnaire (Pre‐MCKQ) were generated from existing questionnaires and supplemented by three experienced ...
Katharina Fischer, Elisabeth Maria Kirschbaum, Lucie Nikoleizig, Franziska Lautenbach, Kerry McGawley, Anne‐Marie Elbe   +5 more
doaj   +1 more source

Using the prototype willingness model to predict doping in sport. [PDF]

, 2014
To enable preventive measures to be designed, it is important to identify modifiable distal and proximal factors underlying doping behavior. This study investigated aspects of the prototype willingness model in relation to doping. A cross-sectional study
Ajzen, Andrews, Backhouse, Blanton, Bloodworth, Fahey, Gibbons, Gibbons, Goulet, Hasking, Hauw, Kirby, Kondric, Kreuter, Lazuras, Lentillon-Kaestner, Lucidi, Mazanov, Melzer, Nulty, Petróczi, Petróczi, Petróczi, Pitsch, Pomery, Rivis, Tabachnick, Thornton, UNESCO, Uvacsek, WADA, Whitaker, Wiefferink, Zimmermann   +33 more
core   +1 more source

Mitochondrial Enzymes Mimetic Ultrasmall Palladium Nanozymes Prevent Senescence and Neurodegeneration Through Metabolic Reprogramming

Advanced Science, EarlyView.
Simply constructed polyvinylpyrrolidone (PVP) modified palladium nanoparticles (PdP NPs) as cytochrome c oxidase (CcO) and superoxide dismutase (SOD) mimic are promising multifunctional nanoreactors to boost mitochondrial respiration chain function and refine homeostasis via regulation of mitochondrial dynamics and proteostasis sensor UPRmt, which ...
Wenshu Cong, Haiming Jing, Zinan Li, Wenjing Zhang, Nan Zhang, Yingqiu Xie, Shan Gao, Yuanyu Huang, Junyu Ning   +8 more
wiley   +1 more source

Image analysis as a basis to the design of wheelchair rugby sportswear [PDF]

, 2018
Sportswear clothing plays a very important part in athletes’ performance. Inappropriate fit puts at risk not only the outcome of the sports event but also the safety of athletes.
Arezes, Pedro, Bragança, Sara, Carvalho, Miguel, Castellucci, Ignacio, Gill, Simeon   +4 more
core   +1 more source

Perfectionism and training distress in junior athletes: A longitudinal investigation [PDF]

, 2016
Perfectionistic athletes may train harder and for longer than non-perfectionistic athletes, leaving them susceptible to elevated levels of training distress.
Antony M. M., Daniel J. Madigan, Flett G. L., Hill A. P., Joachim Stoeber, Louis Passfield, McNair D. M., Raglin J. S., Raglin J. S., Stoeber J., Tabachnick B. G.   +10 more
core   +2 more sources

Bone accrual in oligo-amenorrheic athletes, eumenorrheic athletes and non-athletes [PDF]

Bone, 2019
Mechanical loading improves bone mineral density (BMD) and strength while decreasing fracture risk. Cross-sectional studies show that exercise advantage is lost in oligo-amenorrheic athletes (OA). Longitudinal studies examining the opposing effects of exercise and hypogonadism on bone are lacking in adolescents/young adults.Evaluate differences in bone
Vibha, Singhal, Karen Campoverde, Reyes, Brooke, Pfister, Kathryn, Ackerman, Meghan, Slattery, Katherine, Cooper, Alexander, Toth, Nupur, Gupta, Mark, Goldstein, Kamryn, Eddy, Madhusmita, Misra   +10 more
openaire   +2 more sources

Synchronization‐Dissipation in the Cardiorespiratory System

Advanced Science, EarlyView.
By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border, Alain Nogaret, Andrew Lefevre, Vishal Jain   +3 more
wiley   +1 more source

Beyond the Game: Exploring the Interplay of Career Thoughts, Career Adaptability, and Athletic Identity in Shaping Postgraduation Paths for Student Athletes

Journal of Postsecondary Student Success
College student athletes represent a unique subpopulation of university students. Balancing expectations for academics, practice, and performance leaves little time to engage in thoughtful career exploration and postgraduate planning.
Ryan Sides, Debra S. Osborn, Ivey Walker, Jacob Stamm, Bobbi Villarreal   +4 more
doaj   +1 more source