Results 181 to 190 of about 1,546,576 (211)

Mineralogy and Geochemistry of Some Trace Fossils Filled or Lined with Fecal Pellets from the Cenozoic of the Northern Apennines and the Tunisian Atlas

Anna Spadło, Zbigniew Sawłowicz, Alfred Uchman   +2 more
openalex   +1 more source

Cellular Hallmarks From Volume Electron Microscopy Reveal Developmental Progression of Plasmodium Ookinetes

Advanced Science, EarlyView.
This article presents a detailed ultrastructural cell atlas of Plasmodium ookinete development using advanced volume electron microscopy (v) techniques. It defines seven distinct developmental stages, revealing complex organelle interactions and offering new insights into parasite differentiation.
Nedal Darif, Marco Rheinnecker, Kolja Hildenbrand, Thanat Chookajorn, Lilian P. Dorner, Jean‐Karim Hériché, Sara Henriksson, Charlotta Funaya, Franziska Hentzschel, Linda Sandblad, Oliver Billker, Yannick Schwab, Friedrich Frischknecht   +12 more
wiley   +1 more source

An LCN2‐Dependent Positive‐Feedback Loop Between Gastric Cancer Cells and Tumor‐Associated‐Macrophages Mediates Lymphangiogenesis and Lymphatic Metastasis

Advanced Science, EarlyView.
In this study, the expression and function of LCN2 in GC is aimed to investigate and elucidate the mechanisms by which the LCN2‐dependent positive‐feedback loop between GC cells and TAMs drives lymphangiogenesis and lymphatic metastasis. These findings suggest that LCN2 may serve as a potential prognostic biomarker and therapeutic target in GC ...
Zhixin Huang, Ying Li, Yan Qian, Linying Ye, Tianhao Zhang, Yang Cheng, Jialin Wu, Peng Duan, Tiantian Zhang, Zihan Yu, Zeyu Zhao, Risheng Zhao, Zhi Liang, Ertao Zhai, Shirong Cai, Jianhui Chen   +15 more
wiley   +1 more source

Single‐Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease

Advanced Science, EarlyView.
Using single‐cell RNA sequencing and TCR profiling, this study constructed an immune cell atlas in thyroid tissue of Graves’ disease (GD), revealing dominant IFN‐γ‐secreting CD4+ T cells, expanded Tph and CD11c+ B cells, and enriched T/NK cells. Notably, GD thyroid follicular cells (TFCs) activated γδ T cells, which recruited cDC1 cells, suggesting a ...
Xiaoyi Zhou, Jia Cong, Rongguang Peng, Dichen Yang, Chenchen Dong, Jing Xie, Jiqi Yan, Jie Kuang, Fubin Li, Leng Siew Yeap, Xiaoyan Xie, Haolong Yin, Rulai Han, Liyun Shen, Yulin Zhou, Guang Ning, Shu Wang, Weiqing Wang, Lei Ye   +18 more
wiley   +1 more source

Stage‐Resolved Phosphoproteomic Landscape of Mouse Spermiogenesis Reveals Key Kinase Signaling in Sperm Morphogenesis

Advanced Science, EarlyView.
The quantitative proteomic and phosphoproteomic profiling reveals dynamic phosphorylation regulation of sperm morphogenesis. Kinase‐substrate phosphorylation network and phosphorylation module analysis, followed by in vivo knockdown and knockout analysis, identify TTBK2 and CSNK1G1 as key regulators of morphogenesis, including head, flagellar, and ...
Tianyu Zhu, Yan Zhu, Xinyi Jiang, Xiangzheng Zhang, Bing Wang, Yu Chen, Yichen Zhao, Yulian Wang, Qi Zhou, Zhongyan Han, Yaling Qi, Mengjiao Luo, Haixia Tu, Bingjie Hao, Mengmeng Gao, Jie Ren, Xin Zhou, Xingyu Zhang, Xu Chen, Haojie Li, Qian Huang, Chenghao Situ, Yueshuai Guo, Hui Zhu, Yan Li, Xuejiang Guo   +25 more
wiley   +1 more source

Thyroid Hormone Receptor β1 and PGC1α Coordinately Regulate OPA1/MFN2‐Mediated Mitochondrial Fusion and UCP1‐Mediated Lipid Browning in ccRCC

Advanced Science, EarlyView.
Thyroid hormone receptor β1 (TRβ) downregulation correlates with poor prognosis in clear cell renal cell carcinoma (ccRCC). Restoration of TRβ and the peroxisome proliferator‐activated receptor gamma coactivator 1‐alpha suppresses tumor progression in ccRCC through Uncoupling protein 1 mediated tumor cell “slimming” and optic atrophy 1/mitofusin 2 ...
Xiangui Meng, Tiexi Yu, Fang Lv, Weiquan Li, Hongmei Yang, Xiaoping Zhang, Wen Xiao   +6 more
wiley   +1 more source

Clinically Inspired Multimodal Treatment Using Induced Neural Stem Cells‐Derived Exosomes Promotes Recovery of Traumatic Brain Injury through Microglial Modulation

Advanced Science, EarlyView.
This study explores the therapeutic potential of iNSC‐Exo via local and systemic delivery in TBI mice. It is found that iNSC‐Exo enhances NRXN signaling through Microglia_Nrg3 and Microglia_Rarb, effectively promoting functional and neurological recovery, suggesting a new therapeutic strategy for TBI. Abstract Traumatic brain injury (TBI) poses serious
Jiaojiao Li, Maoxiang Xu, Boyu Cai, Xiangyu Li, Zhanping Liang, Xiaohuan Xia, Haitao Zhang, Zhiwen Zhang, Fei Tan, Jialin Charlie Zheng   +9 more
wiley   +1 more source

Observation of quantum entanglement with top quarks at the ATLAS detector

G. Aad, B. Abbott, K. Abeling, Nils Julius Abicht, S. H. Abidi, A. Aboulhorma, H. Abramowicz, H. Abreu, Y. Abulaiti, B. S. Acharya, C. Adam Bourdarios, L. Adamczyk, S. V. Addepalli, M. J. Addison, J. Adelman, A. Adiguzel, T. Adye, A. A. Affolder, Y. Afik, M. N. Agaras, J. Agarwala, A. Aggarwal, C. Agheorghiesei, A. Ahmad, F. Ahmadov, W. S. Ahmed, S. Ahuja, X. Ai, G. Aielli, A. Aikot, M. Ait Tamlihat, B. Aitbenchikh, I. Aizenberg, M. Akbiyik, T. P. A. Åkesson, A. V. Akimov, D. Akiyama, Nilima Nilesh Akolkar, Sina Aktas, K. Al Khoury, G. L. Alberghi, J. Albert, P. Albicocco, Guillaume Lucas Albouy, S. Alderweireldt, Z. L. Alegria, M. Aleksa, I. N. Aleksandrov, C. Alexa, T. Alexopoulos, F. Alfonsi, M. Algren, M. Alhroob, B. Ali, H. M. J. Ali, S. Ali, Samuel William Alibocus, K. Lie, G. Alimonti, W. Alkakhi, C. Allaire, B. M. M. Allbrooke, Julia Frances Allen, C. Flores, P. P. Allport, A. Aloisio, F. Alonso, C. Alpigiani, M. Alvarez Estevez, A. Álvarez Fernández, M. Alves Cardoso, M. G. Alviggi, M. Aly, Y. Amaral Coutinho, A. Ambler, C. Amelung, M. Amerl, C. G. Ames, D. E. Ferreira de Lima, S. P. Amor Dos Santos, K. R. Amos, V. Ananiev, C. Anastopoulos, T. Andeen, J. K. Anders, S. Y. Andrean, A. Andreazza, S. Angelidakis, A. Angerami, A. V. Anisenkov, A. Annovi, C. Antel, M. T. Anthony, E. Antipov, M. Antonelli, F. F. An, M. Aoki, T. Aoki, J. A. Aparisi Pozo, M. A. Aparo   +99 more
openalex   +1 more source

Microvascular Health as a Key Determinant of Organismal Aging

Advanced Science, EarlyView.
This review spotlights the emerging field of vascular aging, providing a comprehensive and critical overview of the molecular processes and clinical manifestations of vascular dysfunction during aging. By combining basic angioscience concepts with a critical analysis of innovative pre‐clinical aging models and lifestyle interventions, it offers a ...
Mattia Cenciarini, Andrea Uccelli, Francesca Mangili, Myriam Grunewald, Simone Bersini   +4 more
wiley   +1 more source

Search for Planckian Black Holes in the Di-Lepton Channel with the ATLAS Detector at the LHC

, 2011
S. Raddum
openalex   +1 more source