Results 311 to 320 of about 1,930,055 (355)
Neuronal C/EBPβ Shortens the Lifespan via Inactivating NAMPT
Schematic diagram illustrating the mechanism of shortened lifespan in Thy 1‐C/EBPβ transgenic mice and intervention strategies. Briefly, C/EBPβ/AEP escalation in the aging brain triggers NAMPT fragmentation and NAD+ depletion. Knockout of AEP from Thy 1‐C/EBPβ Tg/Tg mice ameliorates cognitive impairments and elongates the lifespan.
Bowei Li+8 more
wiley +1 more source
Preserving Cervical Mobility: A Novel Robot-Assisted Approach for Atlas Fracture Fixation. [PDF]
Yi H, Wang F, Zhang SL, Hu J, Zhang W.
europepmc +1 more source
Pancreatic ductal adenocarcinoma (PDAC) extracellular vesicle (EV) surface protein assay operates via a two‐step workflow – Step 1: Click chemistry‐mediated enrichment of PDAC EVs by EV Click Beads, in the presence of one of the three trans‐cyclooctene‐grafted PDAC EV‐specific antibodies; Step 2: Quantification of the enriched PDAC EVs by reverse ...
Chen Zhao+27 more
wiley +1 more source
Preliminary outcomes of Neuroform Atlas stent-assisted coiling for intracranial aneurysms with small parent vessels. [PDF]
Xiao J+10 more
europepmc +1 more source
Transcriptome Landscape of Cancer‐Associated Fibroblasts in Human PDAC
AP‐1 family members FOS and JUN regulate the malignant phenotype conversion of normal fibroblasts (NFs) to normal‐like cancer‐associated fibroblasts (nCAFs), while transforming growth factor‐β (TGFβ) and interferon‐γ (IFNγ) signals triggers the interconversion between classic myofibroblastic CAFs (myCAFs) and inflammatory CAFs (iCAFs), respectively ...
Mengyu Tao+15 more
wiley +1 more source
New Bipolar Electrosurgical Vessel Sealing Device Provides Improved Performance and Procedural Efficiency. [PDF]
Chambers R, Sarno D, Roweton S.
europepmc +1 more source
During a heart attack, neutrophils rapidly activate and differentiate into a specific subset characterized by high levels of MMP9, a tissue‐damaging enzyme, via the SPI1/CST7 pathway. These neutrophils form harmful net‐like structures (Neutrophil extracellular traps, NETs) that exacerbate heart injury.
Shiyu Hu+13 more
wiley +1 more source