Results 101 to 110 of about 275,008 (315)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Las escuelas de educación artística un espacio para la convivencia, la creatividad y la seguridad

Entretextos
El objetivo del trabajo es conocer a través de las experiencias de los estudiantes y egresados cómo las escuelas de arte son un espacio de convivencia, creatividad y seguridad.
María Navarrete Radilla
doaj   +1 more source

La noción de cuerpo desde la clase de educación física. Manifestaciones sociales.

AiBi Revista de Investigación, Administración e Ingeniería, 2018
Valorar la noción del cuerpo desde la perspectiva de la clase de educación física, para la generación de una aproximación teórica centrada en el disfrute y la satisfacción del ser humano.
Yorley Beatriz Sánchez-Miranda, Arelys Florez-Villamizar   +1 more
doaj   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Da gestão multidimensional à gestão decolonial da educação

Política e Gestão Educacional
A pesquisa reflete sobre a gestão educacional decolonial, centrada na discussão sobre interculturalidade na perspectiva do modelo de gestão educacional multidimensional. Empreendeu-se uma análise temática reflexiva do podcast ‘Essa Geração’, temporada 6
Fabiana Pinto de Almeida Bizarria, Flávia Lorenne Sampaio Barbosa, Telma Maria dos Santos Nascimento, Edileusa Maria Lobato Pereira   +3 more
doaj   +1 more source

Atlas.ti as a tool for analysis of qualitative research according phenomenological approach [PDF]

ETD: Educação Temática Digital, 2014
There’s, in the context of research in the humanities and social sciences, an emerging discussion about the use of new technologies in analytical processes, therefore, what concerns to the use of qualitative or quantitative data analysis software.
Kluber, Tiago Emanuel
doaj  

Summary of the XXVIIth Rencontres de Blois: Particle Physics and Cosmology

, 2015
This writeup summarises some of the highlights from the 2015 Rencontres de Blois, with a compression ratio of about 100:1 relative to the original presentations.Comment: 22 pages, 24 figures, presented at XXVIIth Rencontres de Blois, France, 31 May - 5
Salam, Gavin P.
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Measurement of the total cross section at 8 TeV and the inelastic cross section at 13 TeV at the LHC with the ATLAS detector

, 2016
New measurements from ATLAS at the LHC are presented on the total cross section at $\sqrt{s}=8$ TeV from elastic scattering using the ALFA sub-detector and on the inelastic cross section at $\sqrt{s}=13$ TeV using the MBTS sub-detector.Comment ...
Stenzel, H.
core   +1 more source