Results 241 to 250 of about 1,040,330 (310)

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

Miniaturized Bidirectional Thermal Stimulation System Integrated With an Electrode Array for Recording Neural Activities

Advanced Science, EarlyView.
This study presents a miniaturized bidirectional thermal stimulation system integrated with an electrode array enabling real‐time, bidirectional modulation and simultaneous recording of neural activity through localized heating and cooling. By monolithic integration of the Peltier element and with a silicon neural probe, the innovative system allows ...
Zoia Naumkina, Kanghwan Kim, Wesley Charles Smith, Keuntae Kim, Shinwoo Lee, Jiwan Woo, Il‐Joo Cho   +6 more
wiley   +1 more source

Biocompatibility Evaluation of Surface-Modified Orthodontic Wires Using Graphene Layer. [PDF]

Int J Mol Sci
Rygas J, Szymonowicz M, Rusak A, Wawrzyńska M, Kuropka P, Boiko V, Mielan B, Hreniak D, Dobrzyński M.   +8 more
europepmc   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

A Contrast-Agnostic Method for Ultra-High Resolution Claustrum Segmentation. [PDF]

Hum Brain Mapp
Mauri C, Fritz R, Mora J, Billot B, Iglesias JE, Van Leemput K, Augustinack J, Greve DN.   +7 more
europepmc   +1 more source

White matter resection and verbal memory deficits after temporal lobe epilepsy surgery. [PDF]

Brain Commun
Binding LP, Giampiccolo D, Ji Y, Fleury M, Liu S, Bianchi L, Miserocchi A, McEvoy AW, Baxendale S, Koepp M, Xiao F, O'Keeffe AG, Sidhu MK, Taylor PN, de Tisi J, Winston GP, Duncan JS, Vos SB.   +17 more
europepmc   +1 more source

Tissue-specific and circulatory immune signatures of mucosal inflammation in Crohn’s disease

Ramirez-Navarro L, Jones G, Alegbe T, Harris BT, Strickland M, Ghouraba M, Ostermayer J, Wana N, Hu MX, Skelton J, Garri W, Brezina B, Caballes CQ, Leonard S, Iyer V, McIntyre RE, Parkes M, Martin CC, Anderson CA, Raine T.   +19 more
europepmc   +1 more source

Tissue-derived extracellular vesicles: comparing Ts-EVs and Te-EVs in extraction, characteristics and research trends. [PDF]

Cancer Cell Int
Xue J, Huang D, Zhou H, Qin T, Liu Y, Chen J.   +5 more
europepmc   +1 more source