Results 281 to 290 of about 2,793,510 (386)

Gut Microbiota‐Butyrate‐PPARγ Axis Modulates Adipose Regulatory T Cell Population

Advanced Science, EarlyView.
This study identifies the indispensable role of gut microbiota in the maintenance of ST2+ adipose Treg cell population, and defines gut microbiota‐derived butyrate as an endogenous PPARγ agonist, modulating adipose Treg cell populations via promoting PPARγ activation. Butyrate or fiber supplementation restores the VAT ST2+ Treg population in obese mice
Banru Chen, Lizhi Guan, Chao Wu, Yiwen Gong, Lei Wu, Minchun Zhang, Zhiwen Cao, Yufei Chen, Chengcan Yang, Bing Wang, Yunqi Li, Bin Li, Yufang Bi, Guang Ning, Jiqiu Wang, Weiqing Wang, Ruixin Liu   +16 more
wiley   +1 more source

Ripples formed in low-pressure wind tunnels suggest Mars's large windblown ripples are not impact ripples. [PDF]

Nat Commun
Alvarez CA, Lapôtre MGA, Swann C, Ewing RC.   +3 more
europepmc   +1 more source

The Novel Dual GIP and GLP‐1 Receptor Agonist Tirzepatide Attenuates Colon Cancer Development by Regulating Glucose Metabolism

Advanced Science, EarlyView.
Tirzepatide, a dual GIP/GLP‐1 receptor agonist for diabetes, suppresses colorectal cancer growth by targeting glucose metabolism. It inhibits cancer cell proliferation, promotes apoptosis, and induces tumor regression. It reduces glucose uptake and destabilizes HIF‐1α for degradation to downregulate PFKFB3/PFK‐1 enzymes, thus contributing to the ...
Yikai Zhang, Yi Xie, Shenglong Xia, Xinnuo Ge, Jiaying Li, Fang Liu, Fan Jia, Shengyao Wang, Qiao Zhou, Menghan Gao, Weihuan Fang, Chao Zheng   +11 more
wiley   +1 more source

Stable carbon isotope evolution of formaldehyde on early Mars. [PDF]

Sci Rep
Koyama S, Yoshida T, Furukawa Y, Terada N, Ueno Y, Nakamura Y, Kamada A, Kuroda T, Vandaele AC.   +8 more
europepmc   +1 more source

Escape and evolution of Mars' CO2 atmosphere: Influence of suprathermal atoms

, 2019
Ute Amerstorfer, H. Gröller, Herbert Lichtenegger, H. Lämmer, Feng Tian, Lena Noack, Manuel Scherf, C. P. Johnstone, L. Tu, M. Güdel   +9 more
openalex   +2 more sources

The Upper Atmosphere of Mars

The Astrophysical Journal, 1967
openaire   +2 more sources

Low‐Irradiance Antimicrobial Blue Light‐Bathing Therapy for Wound Infection Control

Advanced Science, EarlyView.
Antimicrobial blue light has been shown as an appealing non‐pharmacological antimicrobial alternative. However, its clinical applications have been hindered by high irradiance‐associated photothermal risks. In this work, a low‐irradiance blue light‐bathing concept and a wearable photonic wound patch are established to address this challenge in terms of
Jie Hui, Wonjoon Moon, Pu‐Ting Dong, Carolina dos Anjos, Laisa Negri, Hao Yan, Ying Wang, Joshua Tam, Tianhong Dai, R. Rox Anderson, Jeremy Goverman, Jeffrey A. Gelfand, Seok‐Hyun Yun   +12 more
wiley   +1 more source

Mars Sample Return: From collection to curation of samples from a habitable world. [PDF]

Proc Natl Acad Sci U S A
McCubbin FM, Farley KA, Harrington AD, Hutzler A, Smith CL.   +4 more
europepmc   +1 more source

Cosmic dust fluxes in the atmospheres of Earth, Mars, and Venus

, 2019
J. D. Carrillo‐Sánchez, Juan Carlos Gómez Martı́n, David L. Bones, David Nesvorný, Petr Pokorný, M. Benna, G. J. Flynn, J. M. C. Plane   +7 more
openalex   +1 more source

Depletion of Hepatic SREBP2 Protects Against Hypercholesterolemia and Atherosclerosis through the ANGPTL3‐LPL Axis

Advanced Science, EarlyView.
This study reveals a novel crosstalk between hepatic SREBP2‐mediated cholesterol biosynthesis pathway and peripheral lipoprotein lipase‐mediated lipolysis pathway in the regulation of systemic lipid metabolism. Notably, the lipid‐lowering effects of SREBP2 inhibition are independent of a functional LDL receptor, highlighting the potential of acute ...
Yifan Wang, Jia You Sarafina Choe, Yu Shi, Thi Tun Thi, Xiaoyun Cao, Yang Hu, Kai Yan Cheng, Hui Li, Yang Ji, Yan Liu, Matthew Ackers‐Johnson, Roger S.Y. Foo, Yujia Shen, Haojie Yu   +13 more
wiley   +1 more source