Results 61 to 70 of about 1,078,393 (352)

ZAP -- Enhanced PCA Sky Subtraction for Integral Field Spectroscopy

, 2016
We introduce Zurich Atmosphere Purge (ZAP), an approach to sky subtraction based on principal component analysis (PCA) that we have developed for the Multi Unit Spectrographic Explorer (MUSE) integral field spectrograph.
Bacon, Roland, Conseil, Simon, Lilly, Simon J., Richard, Johan, Soto, Kurt T.   +4 more
core   +3 more sources

Modeling the variations of Dose Rate measured by RAD during the first MSL Martian year: 2012-2014 [PDF]

, 2015
The Radiation Assessment Detector (RAD), on board Mars Science Laboratory's (MSL) rover Curiosity, measures the {energy spectra} of both energetic charged and neutral particles along with the radiation dose rate at the surface of Mars.
Appel, Jan K., Boehm, Eckart, Boettcher, Stephan, Brinza, David E., Burmeister, Soenke, Ehresmann, Bent, Guo, Jingnan, Hassler, Donald M., Heber, Bernd, Kahanpaeae, H., Koehler, Jan, Lohf, Henning, Martin, Cesar, Posner, Arik, Rafkin, Scot, Reitz, Guenther, Wimmer-Schweingruber, Robert F., Zeitlin, Cary   +17 more
core   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Genetic isolation of an amphidromous goby species, Luciogobius ryukyuensis, highlights limited gene flow in small island populations

Scientific Reports
Amphidromous fish could be transported to other habitats during the marine pelagic larval phase by ocean currents, but extent and mechanism of the larval dispersal is poorly known.
Ken Maeda, Hirozumi Kobayashi, Taiga Uchida, Chuya Shinzato, Ryo Koyanagi, Atsushi J. Nagano, Noriyuki Satoh, Vincent Laudet   +7 more
doaj   +1 more source

Direct Metal Laser Fabrication of Cu Slabs from Powder Precursor: Surface Depth of Melt and Furnace Temperature Issues [PDF]

, 2006
A DMLF processing unit based on a raster-scanned 80 W CO2 laser beam has been developed to process single layers of metallic powder precursor. The process chamber provides atmosphere control (high vacuum and inert gas refill) besides temperature ...
Larraín, Tomás, Ramos-Grez, Jorge, Ramírez, Andrés, Sanz-Guerrero, Jorge   +3 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Asparagopsis taxiformis as a Novel Antioxidant Ingredient for Climate-Smart Aquaculture: Antioxidant, Metabolic and Digestive Modulation in Juvenile White Seabream (Diplodus sargus) Exposed to a Marine Heatwave

Antioxidants
The increasing frequency and duration of marine heatwaves (MHWs) due to climate change pose severe threats to aquaculture, causing drastic physiological and growth impairments in farmed fish, undermining their resilience against additional environmental ...
Alícia Pereira, Isa Marmelo, Marta Dias, Ana Catarina Silva, Ana Catarina Grade, Marisa Barata, Pedro Pousão-Ferreira, Jorge Dias, Patrícia Anacleto, António Marques, Mário S. Diniz, Ana Luísa Maulvault   +11 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source