Results 61 to 70 of about 4,265,733 (351)

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

Surface layer scintillometry for estimating the sensible heat flux component of the surface energy balance

open access: yesSouth African Journal of Science, 2009
The relatively recently developed scintillometry method, with a focus on the dual-beam surface layer scintillometer (SLS), allows boundary layer atmospheric turbulence, surface sensible heat and momentum flux to be estimated in real-time.
G. Odhiambo, M. Savage
doaj  

A Methodology for Comparing the Surface Urban Heat Island in Selected Urban Agglomerations Around the World from Sentinel-3 SLSTR Data

open access: yesRemote Sensing, 2020
Retrieval of land surface temperature (LST) from satellite data allows to estimate the surface urban heat island (SUHI) as the difference between the LST obtained in the urban area and the LST of its surroundings.
José Antonio Sobrino, Itziar Irakulis
doaj   +1 more source

Increasing atmospheric burden of ethanol in the United States

open access: yesGeophysical Research Letters, 2012
The use of ethanol as a transportation fuel in the U.S. increased significantly from 2000–2009, and in 2010 nearly all gasoline contained 10% ethanol. In accordance with this increased use, atmospheric measurements of volatile organic compounds in Los Angeles in 2010 were significantly enriched in ethanol compared to measurements in urban outflow in ...
John S. Holloway   +20 more
openaire   +2 more sources

Atmospheric ammonia and particulate inorganic nitrogen over the United States [PDF]

open access: yesAtmospheric Chemistry and Physics, 2012
Abstract. We use in situ observations from the Interagency Monitoring of PROtected Visual Environments (IMPROVE) network, the Midwest Ammonia Monitoring Project, 11 surface site campaigns as well as Infrared Atmospheric Sounding Interferometer (IASI) satellite measurements with the GEOS-Chem model to investigate inorganic aerosol loading and ...
Randall V. Martin   +15 more
openaire   +9 more sources

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

open access: yesFEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda   +9 more
wiley   +1 more source

The Patient’s Situation During Interhospital Intensive Care Unit-to-Unit Transfers: A Hermeneutical Observational Study

open access: yesQualitative Health Research, 2019
Interhospital intensive care unit-to-unit transfers are an increasing phenomenon, earlier mainly studied from a patient safety perspective. Using data from video recordings and participant observations, the aim was to explore and interpret the observed ...
Jonas Karlsson   +3 more
semanticscholar   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

open access: yesFEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo   +11 more
wiley   +1 more source

Climatology and Trends of Tornado-Favorable Atmospheric Ingredients in the United States

open access: yesAnnals of the American Association of Geographers, 2021
Tornadoes cause numerous fatalities and injuries each year in the United States. Understanding the geographic distribution of tornado risk and how it changes over time is critical to our ability to communicate risk and heighten public awareness and preparation all part of our attempt to reduce the number of tornado-related fatalities and injuries ...
Todd W. Moore   +2 more
openaire   +2 more sources

Starting From Scratch: A White Woman's Journey to Build a Teaching Center Rooted in Adult Learning and Feminist Theories at an HBCU

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This autobiographical article recounts a White woman's efforts to establish a center for teaching and learning (CTL) in a large HBCU in the southern part of the United States. She describes the ways in which tenets of critical feminism, feminist pedagogies, and adult learning and development informed her approach to faculty development.
Audrey Dentith
wiley   +1 more source

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