Results 61 to 70 of about 5,192,191 (348)
Qualitative Health Research, 2019 Interhospital intensive care unit-to-unit transfers are an increasing phenomenon, earlier mainly studied from a patient safety perspective. Using data from video recordings and participant observations, the aim was to explore and interpret the observed ...
Jonas Karlsson +3 more
semanticscholar +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Direct Metal Laser Fabrication of Cu Slabs from Powder Precursor: Surface Depth of Melt and Furnace Temperature Issues [PDF]
, 2006 A DMLF processing unit based on a raster-scanned 80 W CO2 laser beam has been developed to process single layers of metallic powder precursor. The process chamber provides atmosphere control (high vacuum and inert gas refill) besides temperature ...
Larraín, Tomás +3 more
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
UV Exposure during Cycling as a Function of Solar Elevation and Orientation
AtmosphereAlthough cycling is the most prevalent means of locomotion in the world, little research has been done in evaluating the ultraviolet (UV) radiation exposure of cyclists.
Philipp Weihs +8 more
doaj +1 more source
Flare stacks on agricultural biogas plants - safety and operational requirements
Research in Agricultural Engineering, 2019 The flare stack is a piece of equipment, which is used as a safety element at a biogas plant. In the case of a cogeneration unit or gas boiler failure, the biogas is redirected to the flare stack where it is burned. When the flare stack fails, the biogas
Petr Trávníček +5 more
doaj +1 more source
Cubic di-μ-amido-bis[bis(η5-cyclopentadienyl)ytterbium(III)] [PDF]
, 2007 The title compound, [Yb2(C5H5)4(NH2)2], was synthesized in a Parr high-pressure vessel starting from monoclinic [Cp2YbNH2]2 (where Cp = cyclopentadienyl).
Schnick, Wolfgang, Zeuner, Martin
core +1 more source
The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity
FEBS Open Bio, EarlyView.We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda +9 more
wiley +1 more source
, 2015 . In order to better understand the particle size distribution of polycyclic aromatic hydrocarbons (PAHs) and their source contribution to human respiratory system, size-resolved PAHs have been studied in ambient aerosols at a megacity Shanghai site ...
Yan Lv +7 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo +11 more
wiley +1 more source