Results 111 to 120 of about 391,633 (331)
A guide to reactive oxygen species in tumour hypoxia: measurement and therapeutic implications
Molecular Oncology, EarlyView.Hypoxia reshapes tumour redox landscapes by altering compartmental ROS production (mitochondria, NOX, ER, peroxisomes). Accurate interpretation requires oxygen‐contextualised measurement (live biosensors, chemical probes, EPR, LC–MS) and awareness of artefacts (reoxygenation, probe specificity).
Lina Hacker +3 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Atmospheres, Art, and Aesthetics: A Conversation
ESPESInitially conceived as an interview with the hybrid media artist Brian Goeltzenleuchter, this text gradually took the form of a conversation on various issues regarding olfactory art and the aesthetic significance of smell.
Brian Goeltzenleuchter, Elena Mancioppi
doaj
The Effect of Clouds as an Additional Opacity Source on the Inferred Metallicity of Giant Exoplanets
Atmosphere, 2019 Atmospheres regulate the planetary heat loss and therefore influence planetary thermal evolution. Uncertainty in a giant planet’s thermal state contributes to the uncertainty in the inferred abundance of heavy elements it contains.
Anna Julia Poser +2 more
doaj +1 more source
Atmospheric corrosion of zinc in coastal atmospheres
Materials and Corrosion, 2019 The atmospheric corrosion of zinc in pure marine coastal atmospheres has not been extensively studied. This paper presents the results obtained in six pure marine atmospheres located at different distances from the seashore in the same coastal area with annual chloride deposition rates of between 47 and 1142 mg · m−2 · day−1.
María Fuentes +5 more
openaire +3 more sources
The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity
FEBS Open Bio, EarlyView.We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda +9 more
wiley +1 more source
Ambiances, 2019 Gernot Böhme proposes the concept of atmosphere as the basic concept of a new aesthetics without a point of departure in art. This article speculates on some possible urban implications of this concept.
Niels Albertsen
doaj +1 more source
The Presence of Water Vapor in the Atmosphere of Mars Demonstrated by Quantitative Measurements [PDF]
, 1909 Frank W. Very
openalex +1 more source
Infrared spectra of planetary atmospheres [PDF]
The development of high spectral resolution and highly sensitive long infrared wavelength instruments is reported. This instrumentation is used to examine molecular lines in planetary atmospheres in enough detail to obtain new information about these ...
Townes, C. H.
core +1 more source