Results 71 to 80 of about 100,000 (312)
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Atmospherics due to Fronts in the Upper Atmosphere
Journal of geomagnetism and geoelectricity, 1953 For a long time a distinctive tonal distribution of atmospherics has been observed on the Pacific Ocean in lat. 30° to 40°N all the year round especially in autumn and winter. Although they are not so strong as those from southern districts, they are often found even in the interior of Asia at night and have a fairly narrow tonal distribution.Abundant ...
openaire +2 more sources
Nuclear Physics B - Proceedings Supplements, 2000 To be published in the proceedings of TAUP99 Conference College de France - Paris 6-10 September 1999 11 pages 12 ...
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The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
The Response of Tropical Rainfall to Idealized Small‐Scale Thermal and Mechanical Forcing
Geophysical Research LettersPredicting the spatiotemporal distribution of rainfall remains a key challenge in Tropical Meteorology, partly due to an incomplete understanding of the effects of different environmental factors on atmospheric convection.
Martin Velez‐Pardo, Timothy W. Cronin
doaj +1 more source
New Journal of Physics, 2004 Atmospheric neutrinos are produced as decay products in hadronic showers resulting from collisions of cosmic rays with nuclei in the atmosphere. Electron-neutrinos and muon-neutrinos are produced mainly by the decay chain of charged pions to muons to electrons.
openaire +2 more sources
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Dust Plumes Induced by a Time‐Varying Electron Beam
Geophysical Research LettersWe present laboratory results to address dust charging and lofting on the Moon and other airless planetary bodies in response to time‐varying solar wind and ultraviolet (UV) exposure.
A. Cabra, X. Wang, M. Horányi
doaj +1 more source