Results 51 to 60 of about 137,144 (305)

Quantifying the Key Factors Affecting the Escape of Planetary Atmospheres

The Astrophysical Journal, 2023
The habitability of Earth-like planets is an increasingly important subject in astrophysics and in planetary sciences. Atmospheric escape plays a vital role in the evolution of the habitability of Earth-like planets.
J. Luo, H.-Q. He, G.-S. Tong, Jiao Li
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Thermospheric mass density derived in near real time from space debris

Journal of Space Weather and Space Climate
Near-Earth space is becoming increasingly congested. A rapid increase in the number of orbiting objects around Earth underscores the need for accurate tracking and prediction of space objects.
Johlander Andreas, Papadogiannakis Seméli, Rasmusson Ola   +2 more
doaj   +1 more source

Future atmospheric CO2 leads to delayed autumnal senescence

, 2007
Growing seasons are getting longer, a phenomenon partially explained by increasing global temperatures. Recent reports suggest that a strong correlation exists between warming and advances in spring phenology but that a weaker correlation is evident ...
BIRGIT GIELEN, KATRE KETS, Scarascia-Mugnozza, Giuseppe E., GIUSEPPE E. SCARASCIA-MUGNOZZA, MATTHEW J. TALLIS, Gielen, Birgit, Percy, Kevin E., CHRISTIAN P. GIARDINA, Ket, Katre, BENIAMINO GIOLI, Ketss, Katre, Calfaprieta, Carlo, Calfapietra, Carlo, MARK E. KUBISKE, CARLO CALFAPIETRA, Beniamino, Giolis, Gioli, Beniamino, Kubiske, Mark E., DAVID F. KARNOSKY, Migliettas, Franco, FRANCO MIGLIETTA, Scarascia-Mugnozza, Giuseppe, POOJA S. GUPTA, GAIL TAYLOR, Gupta, Pooja S., KEVIN E. PERCY, Karnosky, David F., Miglietta, Franco, Tallis, Matthew J., STEPHEN P. LONG, Gupta, Poojas S., Long, Stephen P., Kets, Katre, Taylor, Gail, Giardina, Christian P.   +34 more
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Forward Simulation of X-Ray Transmittance Profiles in the Martian Atmosphere

Atmosphere
The X-ray occultation technique has emerged as a novel remote sensing method for probing planetary neutral atmospheres, complementing traditional radio and ultraviolet stellar occultations.
Daochun Yu
doaj   +1 more source

Application of electronic and physical techniques to the study of short range atmospheric dispersion and related topics [PDF]

, 1995
Novel instrumental techniques have been conceived, developed and in one case, patented, which were employed to investigate various aspects of atmospheric dispersion and related topics. The first technique made use of unipolarly ionised air as the tracer '
Jones, Christopher D.
core  

Intercomparison of snow density measurements: bias, precision, and vertical resolution [PDF]

, 2016
Density is a fundamental property of porous media such as snow. A wide range of snow properties and physical processes are linked to density, but few studies have addressed the uncertainty in snow density measurements.
C. Fierz, M. Schneebeli, Rutter, Nick, Proksch, Martin, Fierz, Charles, M. Proksch, Schneebeli, Martin, N. Rutter   +7 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source