Results 61 to 70 of about 1,908,606 (375)
Atmospheric Chemistry and Physics, 2018 . Total atmospheric deposition was collected on a weekly basis over 3.5 years (March 2008–October 2011) at a remote coastal site on the west coast of Corsica. Deposition time series of macro- and micronutrients (N, P, Si, Fe) and trace metals (As, Cr, Cu,
K. Desboeufs +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Resources, 2019 Atmospheric resources are very important for assessing ecosystem services at different administrative levels (e.g., state, region, etc.). Quantification of atmospheric calcium (Ca2+) deposition on the total basis provides incomplete information about the
Elena A. Mikhailova +5 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Tellus: Series B, Chemical and Physical Meteorology, 2019 Dry deposition is an important loss process for atmospheric particles and can be a significant part of total deposition estimates calculated for critical loads analyses. However, algorithms used in large-scale air quality and atmospheric chemistry models
Rick D. Saylor +5 more
doaj +1 more source
Nitrate dry deposition in Svalbard [PDF]
Tellus: Series B, Chemical and Physical Meteorology, 2013 Arctic regions are generally nutrient limited, receiving an extensive part of their bio-available nitrogen from the deposition of atmospheric reactive nitrogen.
Mats P. Björkman +9 more
doaj +1 more source
Atmosphere, 2021 Deposition of N and heavy metals can impact ecological and human health. This state-of-the-art review addresses spatial and temporal trends of atmospheric deposition as monitored by element accumulation in moss and compares heavy metals Critical Loads ...
Angela Schlutow +2 more
doaj +1 more source
Mercury deposition in southern New Hampshire, 2006–2009 [PDF]
, 2011 The atmospheric deposition of mercury (Hg) occurs via several mechanisms including wet, dry, and occult processes. In an effort to understand the atmospheric cycling and seasonal depositional characteristics of Hg, event-based wet deposition samples and ...
Bryce, J. G. +3 more
core +2 more sources
Atmospheric Chemistry and Physics, 2018 . Polycyclic aromatic hydrocarbons (PAHs) were analysed in bulk atmospheric deposition samples collected at four European high-mountain areas, Gossenköllesee (Tyrolean Alps), Redon (Central Pyrenees), Skalnate Pleso (High Tatra Mountains), and Lochnagar (
L. Arellano +9 more
semanticscholar +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source