Results 71 to 80 of about 695,317 (311)

Efficient Multigrid Preconditioners for Atmospheric Flow Simulations at High Aspect Ratio [PDF]

, 2015
Many problems in fluid modelling require the efficient solution of highly anisotropic elliptic partial differential equations (PDEs) in "flat" domains. For example, in numerical weather- and climate-prediction an elliptic PDE for the pressure correction ...
Adams, Adams, Ashby, Baker, Barros, Bastian, Bastian, Bastian, Bates, Bey, Bowman, Brandt, Buckeridge, Buckeridge, Burri, Börm, Chen, Cotter, Cotter, Crank, Davies, De Zeeuw, Dedner, Dendy, Dendy, Falgout, Falgout, Fringer, Hackbusch, Hackbusch, Hackbusch, Hess, Ippisch, Kwizak, Lacroix, MacDonald, Marshall, Mavriplis, Mulder, Müller, Müller, Oosterlee, Oosterlee, Press, Qaddouri, Reisinger, Robert, Saad, Sadourny, Schaffer, Skamarock, Staniforth, Stüben, Thomas, Trottenberg, Vorst, Wesseling, Wood   +57 more
core   +2 more sources

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Data assimilation of generic boundary layer flows for wind turbine applications – an LES study [PDF]

Wind Energy Science
Providing date- and site-specific turbulent inflow fields for large-eddy simulations (LESs) of the flow through wind turbines becomes increasingly important for reliable estimates of power production.
L. Wrba, A. Englberger, A. Dörnbrack, G. Kilroy, N. Wildmann   +4 more
doaj   +1 more source

Noise produced by turbulent flow into a rotor: Theory manual for atmospheric turbulence prediction and mean flow and turbulence contraction prediction [PDF]

Prediction of helicopter main rotor noise due to ingestion of atmospheric turbulence was analyzed. The analysis combines several different models that describe the fluid mechanics of the turbulence and the ingestion process.
Simonich, J. C.
core   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Topographic Precipitation Diagnosis: Model Design and Validation in a Two-Dimensional Context

Atmosphere
This study develops a two-dimensional (z-x direction) atmospheric dynamics model based on a set of simplified atmospheric motion equations, designed for rapid simulation of atmospheric flow characteristics over complex terrains.
Xiangqian Wei, Yi Liu, Cong Cheng, Xinyu Chang, Jun Guo   +4 more
doaj   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Hypersonic aerodynamic problems at re-entry of space vehicles [PDF]

Hypersonic aerodynamic problems at space vehicle reentry - plasma effects on communications blackout, hypersonic flow, and atmospheric ...
Hermann, R.
core   +1 more source

Eclipsing light curves for accretion flows around a rotating black hole and atmospheric effects of the companion star

, 2007
We calculate eclipsing light curves for accretion flows around a rotating black hole taking into account the atmospheric effects of the companion star.
Takahashi, Rohta, Watarai, Ken-Ya
core   +1 more source

Experimental Evaluation of 100Cr6 Steel Microindented Surfaces Under Lubricated Nonconformal Point Contacts

Advanced Engineering Materials, EarlyView.
The tribological behavior of 100Cr6 steel spheres textured via Vickers microindentation is evaluated under lubricated sliding by varying both dimple size and density. Fine and dense textures significantly reduce friction across all lubrication regimes, while large dimples increase it.
Farideh Davoodi, Pasquale Guglielmi, Gianfranco Palumbo, Giuseppe Carbone   +3 more
wiley   +1 more source