Results 91 to 100 of about 1,109 (265)
Advanced Materials Technologies, EarlyView.Desktop vacuum thermoforming enables rapid, low‐cost fabrication of 96‐channel polystyrene culture chips with very thin imaging interfaces. The resulting platform supports cell lines, primary cells, and patient‐derived organoids, and enables high‐resolution confocal microscopy and single‐cell visualization, providing an accessible approach for advanced
Aleksandra Fomina +5 more
wiley +1 more source
Self‐Sealing Microneedles Improve Precision and Reduce Reflux in Subretinal Cell Transplantation
Advanced Materials Technologies, EarlyView.Ultrafine 49G microneedles enable subretinal delivery of induced pluripotent stem cell‐derived retinal pigment epithelial cells through a 50 µm outer diameter tip. Compared with conventional 38G microcannulas, these microneedles reduce cell suspension reflux in a rabbit model, highlighting the potential of microinvasive delivery instruments to improve ...
Jared Ching +9 more
wiley +1 more source
Advanced Robotics Research, EarlyView.A magnetic donut‐like millirobot is developed for label‐free pick‐and‐place of a tumor spheroid wirelessly controlled by a magnetic trap. Spheroids are important 3D multicellular culture systems that recapitulate key structural and functional features of native tissues.
Yue Gao +8 more
wiley +1 more source
Dual‐Mode Gripper With Suction and Shape‐Adaptive Freezing Grasps
Advanced Robotics Research, EarlyView.This study presents a dual‐mode robotic gripper that combines vacuum suction with a shape‐adaptive freezing grasp. The freezing mode uses a compliant rubber membrane, a sprayed water layer, and dry‐ice powder to generate ice‐mediated adhesion while conforming to complex geometries.
Takuma Yanagisawa +4 more
wiley +1 more source
Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Advanced Science, EarlyView.Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source
Ice clouds in the Martian atmosphere
Journal of the Japanese Society of Snow and Ice, 2005 近年の探査衛星観測により火星の気象学的観測データの量が飛躍的に増加したことから,火星大気の氷雲の科学を定量的に論ずることが可能となってきた.火星のH2O氷雲は受動的トレーサであるため,その分布を調べることで直接観測が困難な火星大気の流れ場に関する情報を得ることができる.従来直接観測が困難であった極夜のCO2氷雲は,マーズグローバルサーベイヤーのレーザー高度計によりその存在が初めて明らかとなった.CO2氷雲は過去の火星の気候を考える上でも重要な要素である.過去に火星で実現していた温暖な気候を維持するには,厚いCO2大気にともなうCO2氷雲の温室効果が寄与していたのではないかと考えられているからである.CO2氷雲の形成過程と消散係数などの放射パラメータを調べることにより ...
openaire +2 more sources
Advanced Science, EarlyView.Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong +24 more
wiley +1 more source
Advanced Science, EarlyView.Using single‐cell transcriptomic and epigenomic profiling, researchers mapped microglial dysfunction across the lifespan of db/db mice. The authors uncovered a nonlinear microglial remodeling featuring early inflammatory priming, a mid‐stage transcriptional inflection, and late dysfunction.
Jizhou Zhang +6 more
wiley +1 more source
Iodine in Sea Ice and the Polar Atmosphere [PDF]
, 2011 The volatilisation of iodine from the ocean and release to the atmosphere in the ice-covered polar regions has been studied. Laboratory experiments involving sea ice- and ice associated- diatoms have shown how the extreme conditions experienced in sea ice brine channels may lead to an increase in production of organic forms of iodine.
openaire +1 more source
Advanced Science, EarlyView.Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang +3 more
wiley +1 more source