Results 41 to 50 of about 15,844 (355)
Applied SciencesThis study presents a numerical investigation of the effects of atmospheric icing on the aerodynamic performance and power output of the NREL 5 MW reference wind turbine.
Berkay Öztürk, Eyup Koçak
doaj +1 more source
Meteorologische Zeitschrift, 2017 The Advanced Diagnosis and Warning System for Aircraft Icing Environments (ADWICE) has been in development since 1998 in a collaboration between the German Aerospace Centre (DLR), Deutscher Wetterdienst (German Weather Service, DWD) and the Institute of ...
Frank Kalinka +3 more
doaj +1 more source
Stability of Vessels in an Ice-free Arctic [PDF]
TransNav, 2020 One consequence of the declining ice cover in the Arctic is increased areas of open seas. These new open sea areas lead to some challenging aspects related to ship stability.
KÁre Johansen +2 more
doaj +1 more source
Overview of FAA's aircraft icing program [PDF]
, 1985 An overview of the FAA's icing program is presented. The program involves certification of various types of aircraft for flight in known icing conditions, the study of icing conditions, and the preparation of certification standards.
Czekalski, L.
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Ice Nucleation in the Atmosphere [PDF]
Atmosphere, 2019 Ice particles in the atmosphere contribute to the largest uncertainty in interpretations of the Earth’s changing energy budget [...]
openaire +2 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source