Results 51 to 60 of about 15,844 (355)

Development of a multifunctional panel for aerospace use through SLM additive manufacturing [PDF]

, 2018
Lattice materials can overcome the need of light and stiff structures in the aerospace industry. The wing leading edge is one of the most critical parts for both on-board subsystem and structure features: it must withstand to the aerodynamic loads and ...
Bici, Michele, Brischetto, Salvatore, Campana, Francesca, Ferro, Carlo Giovanni, Maggiore, Paolo, Mazza, Andrea, Seclì, Carlo, Varetti, Sara   +7 more
core   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

A Review of Icing Research and Development of Icing Mitigation Techniques for Fixed-Wing UAVs

Drones, 2023
With the continuous expansion of Unmanned Aerial Vehicle (UAV) applications, the threat of icing on UAV flights has garnered increased attention. Understanding the icing principles and developing anti-icing technologies for unmanned aircraft is a crucial
Liang Zhou, Xian Yi, Qinglin Liu
doaj   +1 more source

Polarimetric radar studies of atmospheric ice particles [PDF]

IEEE Transactions on Geoscience and Remote Sensing, 1994
Single scattering properties of ice crystals are described at microwave frequencies using discrete dipole approximations and Rayleigh scattering techniques. For a given shape, the average bulk densities of ice crystals can be estimated using the ratio of the copolarized radar signal in a linear (horizontal, vertical) polarization basis.
Vivekanandan, J. (1), Bringi, V.N. (2)), Hagen, M., Meischner, P.   +3 more
openaire   +2 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Modeling of ice accretion on a non-rotating cylinder

Meteorologische Zeitschrift, 1997
A time-dependent numerical model is developed for the description of icing on an unheated, non-rotating cylinder in supercooled water clouds. The model predicts, with consideration of the effect of roughness and shape, the mass and profile of ice ...
Klaus Arnold, Gerd Tetzlaff, Armin Raabe
doaj   +1 more source

Optimal control of the heave motion of marine cable subsea-unit systems [PDF]

, 1995
One of the key problems associated with subsea operations involving tethered subsea units is the motions of support vessels on the ocean surface which can be transmitted to the subsea unit through the cable and increase the tension.
Huang, S., Vassalos, D.
core  

Atmospheric Ice Formation Processes

, 2012
This contribution provides a basic introduction to the formation of ice in clouds. Various pathways to ice nucleation and factors controlling ice formation processes are addressed. Challenges in characterizing the atmospheric ice phase and novel approaches to better understanding the fundamental mechanisms involved in ice nucleation are outlined.
openaire   +2 more sources

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source