Results 41 to 50 of about 176,247 (337)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Atmosphere, 2020 The tropical region is a key area for the interaction between the stratosphere and troposphere. The strong convective activity in the troposphere produces a series of gravity wave activities, which result in strong and widespread turbulence over the ...
Yang He +4 more
doaj +1 more source
Multiple equilibria and oscillatory modes in a mid-latitude ocean-forced atmospheric model [PDF]
Nonlinear Processes in Geophysics, 2012 Atmospheric response to a mid-latitude sea surface temperature (SST) front is studied, while emphasizing low-frequency modes induced by the presence of such a front.
B. Deremble, E. Simonnet, M. Ghil
doaj +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Tangling clustering instability for small particles in temperature stratified turbulence
, 2013 We study particle clustering in a temperature stratified turbulence with small finite correlation time. It is shown that the temperature stratified turbulence strongly increases the degree of compressibility of particle velocity field.
Elperin, Tov +3 more
core +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.The corrosion performance of AlSi7Mg and AlSi10Mg alloys produced through selective laser melting (SLM) was examined under compressive stress in a chloride environment. Electrochemical analyses, including open‐circuit potential (OCP), potentiodynamic polarization (CPP), and electrochemical impedance spectroscopy (EIS), were complemented by scanning ...
Femi John Akinfolarin +2 more
wiley +1 more source
Atmosphere, 2021 The heavy precipitation in Northern California—brought about by a landfalling atmospheric river (AR) on 25–27 February 2019—is investigated for an understanding of the underlying dynamical processes.
Zhuang Zhang, X. San Liang
doaj +1 more source
The Nature of the Driving Mechanism in the Pulsating Hybrid PG 1159 Star Abell 43
, 2005 We extend our previous pulsational stability analyses of PG 1159 stars by modeling the hybrid PG 1159 type star Abell 43. We show that the standard kappa-mechanism due to the ionization of C and O in the envelope of this H-rich PG 1159 star is perfectly ...
Ciardullo +17 more
core +1 more source